Nosocomial outbreak of vancomycin-resistant Enterococcus faecium at a German university pediatric hospital.
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Nosocomial outbreak of vancomycin-resistant Enterococcus faecium at a German university pediatric hospital. / Elsner, H A; Sobottka, Ingo; Feucht, H H; Harps, E; Haun, C; Mack, D; Ganschow, Rainer; Laufs, R; Kaulfers, P M.
In: INT J HYG ENVIR HEAL, Vol. 203, No. 2, 2, 2000, p. 147-152.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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T1 - Nosocomial outbreak of vancomycin-resistant Enterococcus faecium at a German university pediatric hospital.
AU - Elsner, H A
AU - Sobottka, Ingo
AU - Feucht, H H
AU - Harps, E
AU - Haun, C
AU - Mack, D
AU - Ganschow, Rainer
AU - Laufs, R
AU - Kaulfers, P M
PY - 2000
Y1 - 2000
N2 - Nosocomial Infections caused by vancomycin-resistant enterococci (VRE) are an emerging threat to critically ill patients. At the University Hospital Eppendorf, VRE were isolated from 38 patients between August 1993 and April 1997, of whom 32 were hospitalized at the Department of Pediatrics. Pulsed-field gel electrophoresis revealed that 26 Enterococcus faecium isolates from patients of the Department of Pediatrics were identical or closely related, and that isolates from three additional patients of the same department were possibly related. All of these isolates were of vanA genotype. They were resistant to glycopeptides, ampicillin, ciprofloxacin, clindamycin, and erythromycin. Most isolates displayed high-level resistance to gentamicin, but all remained susceptible to quinupristin/dalfopristin. Implementation of stringent hand disinfection and environmental disinfection policies, as well as measures for patient isolation contained this first outbreak of VRE at a German Children's hospital, which emphasizes the importance of hygienic measures for the control of nosocomial spread of these organisms.
AB - Nosocomial Infections caused by vancomycin-resistant enterococci (VRE) are an emerging threat to critically ill patients. At the University Hospital Eppendorf, VRE were isolated from 38 patients between August 1993 and April 1997, of whom 32 were hospitalized at the Department of Pediatrics. Pulsed-field gel electrophoresis revealed that 26 Enterococcus faecium isolates from patients of the Department of Pediatrics were identical or closely related, and that isolates from three additional patients of the same department were possibly related. All of these isolates were of vanA genotype. They were resistant to glycopeptides, ampicillin, ciprofloxacin, clindamycin, and erythromycin. Most isolates displayed high-level resistance to gentamicin, but all remained susceptible to quinupristin/dalfopristin. Implementation of stringent hand disinfection and environmental disinfection policies, as well as measures for patient isolation contained this first outbreak of VRE at a German Children's hospital, which emphasizes the importance of hygienic measures for the control of nosocomial spread of these organisms.
M3 - SCORING: Zeitschriftenaufsatz
VL - 203
SP - 147
EP - 152
JO - INT J HYG ENVIR HEAL
JF - INT J HYG ENVIR HEAL
SN - 1438-4639
IS - 2
M1 - 2
ER -
