Non-invasive diagnosis and monitoring of liver fibrosis and cirrhosis.

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Non-invasive diagnosis and monitoring of liver fibrosis and cirrhosis. / Denzer, Ulrike W.; Lüth, Stefan.

In: BEST PRACT RES CL GA, Vol. 23, No. 3, 3, 2009, p. 453-460.

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@article{d5d00b38e8e14fb5b2ca909f1674f9b2,
title = "Non-invasive diagnosis and monitoring of liver fibrosis and cirrhosis.",
abstract = "The accurate staging of liver fibrosis in chronic liver diseases, especially the early diagnosis of liver cirrhosis, is crucial for prognostic assessment of the course of the disease. The histological evaluation of a liver biopsy cylinder is still the gold standard in assessing the stage of liver fibrosis. However, liver biopsy is an invasive procedure and carries the risk of complications. This has to be balanced against the information benefit of liver histology. To overcome this, non-invasive tests were developed assessing liver fibrosis based on combinations of laboratory markers or techniques measuring liver elasticity. In this review the current impact of the non invasive methods is discussed and weighted against liver biopsy.",
author = "Denzer, {Ulrike W.} and Stefan L{\"u}th",
year = "2009",
language = "Deutsch",
volume = "23",
pages = "453--460",
journal = "BEST PRACT RES CL GA",
issn = "1521-6918",
publisher = "Bailliere Tindall Ltd",
number = "3",

}

RIS

TY - JOUR

T1 - Non-invasive diagnosis and monitoring of liver fibrosis and cirrhosis.

AU - Denzer, Ulrike W.

AU - Lüth, Stefan

PY - 2009

Y1 - 2009

N2 - The accurate staging of liver fibrosis in chronic liver diseases, especially the early diagnosis of liver cirrhosis, is crucial for prognostic assessment of the course of the disease. The histological evaluation of a liver biopsy cylinder is still the gold standard in assessing the stage of liver fibrosis. However, liver biopsy is an invasive procedure and carries the risk of complications. This has to be balanced against the information benefit of liver histology. To overcome this, non-invasive tests were developed assessing liver fibrosis based on combinations of laboratory markers or techniques measuring liver elasticity. In this review the current impact of the non invasive methods is discussed and weighted against liver biopsy.

AB - The accurate staging of liver fibrosis in chronic liver diseases, especially the early diagnosis of liver cirrhosis, is crucial for prognostic assessment of the course of the disease. The histological evaluation of a liver biopsy cylinder is still the gold standard in assessing the stage of liver fibrosis. However, liver biopsy is an invasive procedure and carries the risk of complications. This has to be balanced against the information benefit of liver histology. To overcome this, non-invasive tests were developed assessing liver fibrosis based on combinations of laboratory markers or techniques measuring liver elasticity. In this review the current impact of the non invasive methods is discussed and weighted against liver biopsy.

M3 - SCORING: Zeitschriftenaufsatz

VL - 23

SP - 453

EP - 460

JO - BEST PRACT RES CL GA

JF - BEST PRACT RES CL GA

SN - 1521-6918

IS - 3

M1 - 3

ER -