No effect of the transforming growth factor β1 promoter polymorphism C-509T on TGFB1 gene expression, protein secretion, or cellular radiosensitivity.
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No effect of the transforming growth factor β1 promoter polymorphism C-509T on TGFB1 gene expression, protein secretion, or cellular radiosensitivity. / Reuther, Sebastian; Metzke, Elisabeth; Bonin, Michael; Petersen, Cordula; Dikomey, Ekkehard; Raabe, Annette.
In: INT J RADIAT ONCOL, Vol. 85, No. 2, 2, 2013, p. 460-465.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - No effect of the transforming growth factor β1 promoter polymorphism C-509T on TGFB1 gene expression, protein secretion, or cellular radiosensitivity.
AU - Reuther, Sebastian
AU - Metzke, Elisabeth
AU - Bonin, Michael
AU - Petersen, Cordula
AU - Dikomey, Ekkehard
AU - Raabe, Annette
PY - 2013
Y1 - 2013
N2 - To study whether the promoter polymorphism (C-509T) affects transforming growth factor ?1 gene (TGFB1) expression, protein secretion, and/or cellular radiosensitivity for both human lymphocytes and fibroblasts.
AB - To study whether the promoter polymorphism (C-509T) affects transforming growth factor ?1 gene (TGFB1) expression, protein secretion, and/or cellular radiosensitivity for both human lymphocytes and fibroblasts.
KW - Humans
KW - Male
KW - Female
KW - Genotype
KW - Reverse Transcriptase Polymerase Chain Reaction
KW - Protein Array Analysis/methods
KW - Colony-Forming Units Assay
KW - Polymorphism, Single Nucleotide/physiology
KW - Promoter Regions, Genetic/physiology
KW - Radiation Tolerance/genetics
KW - Transforming Growth Factor beta1/genetics/metabolism
KW - Breast Neoplasms
KW - Fibroblasts/metabolism/radiation effects
KW - Gene Expression Regulation/genetics/radiation effects
KW - Lymphocytes/metabolism/radiation effects
KW - Twins, Monozygotic
KW - Humans
KW - Male
KW - Female
KW - Genotype
KW - Reverse Transcriptase Polymerase Chain Reaction
KW - Protein Array Analysis/methods
KW - Colony-Forming Units Assay
KW - Polymorphism, Single Nucleotide/physiology
KW - Promoter Regions, Genetic/physiology
KW - Radiation Tolerance/genetics
KW - Transforming Growth Factor beta1/genetics/metabolism
KW - Breast Neoplasms
KW - Fibroblasts/metabolism/radiation effects
KW - Gene Expression Regulation/genetics/radiation effects
KW - Lymphocytes/metabolism/radiation effects
KW - Twins, Monozygotic
M3 - SCORING: Journal article
VL - 85
SP - 460
EP - 465
JO - INT J RADIAT ONCOL
JF - INT J RADIAT ONCOL
SN - 0360-3016
IS - 2
M1 - 2
ER -