Nitroalkylation--a redox sensitive signaling pathway

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Nitroalkylation--a redox sensitive signaling pathway. / Geisler, Anne C; Rudolph, Tanja K.

In: Biochim Biophys Acta, Vol. 1820, No. 6, 06.2012, p. 777-784.

Research output: SCORING: Contribution to journalSCORING: Review articleResearch

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@article{a7248b03596a4c03b7005bfc876ceec6,
title = "Nitroalkylation--a redox sensitive signaling pathway",
abstract = "Redox-sensitive posttranslational modification emerged as important signaling mechanisms. Besides other posttranslational modifications nitroalkylation by nitrated fatty acids mediate favorable anti-inflammatory effects. This review gives an overview of the generation and the reactivity of nitrated fatty acids. Additionally, it provides insights into the so far described pathways regulated by nitrated fatty acids. This article is part of a Special Issue entitled Regulation of Cellular Processes by S-nitrosylation.",
keywords = "Alkylation, Animals, Fatty Acids/metabolism, Heme Oxygenase-1/metabolism, Humans, Matrix Metalloproteinases/genetics, NF-E2-Related Factor 2/metabolism, NF-kappa B/metabolism, Nitrates/metabolism, Nitric Oxide/chemistry, Nitrosation/physiology, Oxidation-Reduction, PPAR gamma/metabolism, Protein Processing, Post-Translational, STAT1 Transcription Factor/antagonists & inhibitors, Signal Transduction",
author = "Geisler, {Anne C} and Rudolph, {Tanja K}",
note = "Copyright {\textcopyright} 2011 Elsevier B.V. All rights reserved.",
year = "2012",
month = jun,
doi = "10.1016/j.bbagen.2011.06.014",
language = "English",
volume = "1820",
pages = "777--784",
journal = "Biochim Biophys Acta",
issn = "0006-3002",
number = "6",

}

RIS

TY - JOUR

T1 - Nitroalkylation--a redox sensitive signaling pathway

AU - Geisler, Anne C

AU - Rudolph, Tanja K

N1 - Copyright © 2011 Elsevier B.V. All rights reserved.

PY - 2012/6

Y1 - 2012/6

N2 - Redox-sensitive posttranslational modification emerged as important signaling mechanisms. Besides other posttranslational modifications nitroalkylation by nitrated fatty acids mediate favorable anti-inflammatory effects. This review gives an overview of the generation and the reactivity of nitrated fatty acids. Additionally, it provides insights into the so far described pathways regulated by nitrated fatty acids. This article is part of a Special Issue entitled Regulation of Cellular Processes by S-nitrosylation.

AB - Redox-sensitive posttranslational modification emerged as important signaling mechanisms. Besides other posttranslational modifications nitroalkylation by nitrated fatty acids mediate favorable anti-inflammatory effects. This review gives an overview of the generation and the reactivity of nitrated fatty acids. Additionally, it provides insights into the so far described pathways regulated by nitrated fatty acids. This article is part of a Special Issue entitled Regulation of Cellular Processes by S-nitrosylation.

KW - Alkylation

KW - Animals

KW - Fatty Acids/metabolism

KW - Heme Oxygenase-1/metabolism

KW - Humans

KW - Matrix Metalloproteinases/genetics

KW - NF-E2-Related Factor 2/metabolism

KW - NF-kappa B/metabolism

KW - Nitrates/metabolism

KW - Nitric Oxide/chemistry

KW - Nitrosation/physiology

KW - Oxidation-Reduction

KW - PPAR gamma/metabolism

KW - Protein Processing, Post-Translational

KW - STAT1 Transcription Factor/antagonists & inhibitors

KW - Signal Transduction

U2 - 10.1016/j.bbagen.2011.06.014

DO - 10.1016/j.bbagen.2011.06.014

M3 - SCORING: Review article

C2 - 21723375

VL - 1820

SP - 777

EP - 784

JO - Biochim Biophys Acta

JF - Biochim Biophys Acta

SN - 0006-3002

IS - 6

ER -