New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany

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New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany. / Heinrich, Fabian; Huter, Tobias; Mertens, Sophie; Lange, Philine; Vering, Jessica; Heinemann, Axel; Nörz, Dominik Sebastian; Hoffmann, Armin; Aepfelbacher, Martin; Ondruschka, Benjamin; Krasemann, Susanne; Lütgehetmann, Marc.

In: EMERG INFECT DIS, Vol. 29, No. 3, 03.2023, p. 652-656.

Research output: SCORING: Contribution to journalLetterResearchpeer-review

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@article{e1fe13ee0e0c4d52adf0709fca5fa5d4,
title = "New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany",
abstract = "We performed autopsies on persons in Germany who died from COVID-19 and observed higher nasopharyngeal SARS-CoV-2 viral loads for variants of concern (VOC) compared with non-VOC lineages. Pulmonary inflammation and damage appeared higher in non-VOC than VOC lineages until adjusted for vaccination status, suggesting COVID-19 vaccination may mitigate pulmonary damage.",
author = "Fabian Heinrich and Tobias Huter and Sophie Mertens and Philine Lange and Jessica Vering and Axel Heinemann and N{\"o}rz, {Dominik Sebastian} and Armin Hoffmann and Martin Aepfelbacher and Benjamin Ondruschka and Susanne Krasemann and Marc L{\"u}tgehetmann",
year = "2023",
month = mar,
doi = "10.3201/eid2903.221297",
language = "English",
volume = "29",
pages = "652--656",
journal = "EMERG INFECT DIS",
issn = "1080-6040",
publisher = "Centers for Disease Control and Prevention (CDC)",
number = "3",

}

RIS

TY - JOUR

T1 - New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany

AU - Heinrich, Fabian

AU - Huter, Tobias

AU - Mertens, Sophie

AU - Lange, Philine

AU - Vering, Jessica

AU - Heinemann, Axel

AU - Nörz, Dominik Sebastian

AU - Hoffmann, Armin

AU - Aepfelbacher, Martin

AU - Ondruschka, Benjamin

AU - Krasemann, Susanne

AU - Lütgehetmann, Marc

PY - 2023/3

Y1 - 2023/3

N2 - We performed autopsies on persons in Germany who died from COVID-19 and observed higher nasopharyngeal SARS-CoV-2 viral loads for variants of concern (VOC) compared with non-VOC lineages. Pulmonary inflammation and damage appeared higher in non-VOC than VOC lineages until adjusted for vaccination status, suggesting COVID-19 vaccination may mitigate pulmonary damage.

AB - We performed autopsies on persons in Germany who died from COVID-19 and observed higher nasopharyngeal SARS-CoV-2 viral loads for variants of concern (VOC) compared with non-VOC lineages. Pulmonary inflammation and damage appeared higher in non-VOC than VOC lineages until adjusted for vaccination status, suggesting COVID-19 vaccination may mitigate pulmonary damage.

U2 - 10.3201/eid2903.221297

DO - 10.3201/eid2903.221297

M3 - Letter

C2 - 36787498

VL - 29

SP - 652

EP - 656

JO - EMERG INFECT DIS

JF - EMERG INFECT DIS

SN - 1080-6040

IS - 3

ER -