[New aspects of HPV-positive head and neck cancer. Highlights from the 2011 ASCO Congress].
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[New aspects of HPV-positive head and neck cancer. Highlights from the 2011 ASCO Congress]. / Kofler, Barbara; Uecker, Florian C.; Münscher, Adrian; Knecht, Rainald.
In: HNO, Vol. 60, No. 5, 5, 2012, p. 404-407.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - [New aspects of HPV-positive head and neck cancer. Highlights from the 2011 ASCO Congress].
AU - Kofler, Barbara
AU - Uecker, Florian C.
AU - Münscher, Adrian
AU - Knecht, Rainald
PY - 2012
Y1 - 2012
N2 - HPV-positive head and neck carcinoma is significantly different than tobacco- and alcohol-induced cancer. Between 30% and 50% of oropharyngeal cancers are associated with human papillomavirus (HPV). Studies still show an increasing incidence. HPV-positive head and neck cancer patients have a better prognosis due to a better response to therapy. Especially patients with gene overexpression of immunological proteins in the antigen presentation are suggested to benefit from radiotherapy. A current retrospective study shows better outcomes for patients treated with radiotherapy in combination with biological targets compared to radiochemotherapy.
AB - HPV-positive head and neck carcinoma is significantly different than tobacco- and alcohol-induced cancer. Between 30% and 50% of oropharyngeal cancers are associated with human papillomavirus (HPV). Studies still show an increasing incidence. HPV-positive head and neck cancer patients have a better prognosis due to a better response to therapy. Especially patients with gene overexpression of immunological proteins in the antigen presentation are suggested to benefit from radiotherapy. A current retrospective study shows better outcomes for patients treated with radiotherapy in combination with biological targets compared to radiochemotherapy.
KW - Humans
KW - Papillomaviridae/isolation & purification
KW - Evidence-Based Medicine/trends
KW - Chemoradiotherapy/trends
KW - Head and Neck Neoplasms/therapy/virology
KW - Molecular Targeted Therapy/trends
KW - Humans
KW - Papillomaviridae/isolation & purification
KW - Evidence-Based Medicine/trends
KW - Chemoradiotherapy/trends
KW - Head and Neck Neoplasms/therapy/virology
KW - Molecular Targeted Therapy/trends
M3 - SCORING: Zeitschriftenaufsatz
VL - 60
SP - 404
EP - 407
JO - HNO
JF - HNO
SN - 0017-6192
IS - 5
M1 - 5
ER -