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Neuropsychological short assessment of disease- and treatment-related intelligence deficits in children with brain tumours

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Neuropsychological short assessment of disease- and treatment-related intelligence deficits in children with brain tumours. / Ottensmeier, Holger; Zimolong, Bernhard; Wolff, Johannes E; Ehrich, Jochen; Galley, Niels; von Hoff, Katja; Kuehl, Joachim; Rutkowski, Stefan.

In: EUR J PAEDIATR NEURO, Vol. 19, No. 3, 05.2015, p. 298-307.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Ottensmeier, H, Zimolong, B, Wolff, JE, Ehrich, J, Galley, N, von Hoff, K, Kuehl, J & Rutkowski, S 2015, 'Neuropsychological short assessment of disease- and treatment-related intelligence deficits in children with brain tumours', EUR J PAEDIATR NEURO, vol. 19, no. 3, pp. 298-307. https://doi.org/10.1016/j.ejpn.2014.12.019

APA

Ottensmeier, H., Zimolong, B., Wolff, J. E., Ehrich, J., Galley, N., von Hoff, K., Kuehl, J., & Rutkowski, S. (2015). Neuropsychological short assessment of disease- and treatment-related intelligence deficits in children with brain tumours. EUR J PAEDIATR NEURO, 19(3), 298-307. https://doi.org/10.1016/j.ejpn.2014.12.019

Vancouver

Ottensmeier H, Zimolong B, Wolff JE, Ehrich J, Galley N, von Hoff K et al. Neuropsychological short assessment of disease- and treatment-related intelligence deficits in children with brain tumours. EUR J PAEDIATR NEURO. 2015 May;19(3):298-307. https://doi.org/10.1016/j.ejpn.2014.12.019

Bibtex

@article{1cdbb35431b945cca1c1091bbd3713b5,
title = "Neuropsychological short assessment of disease- and treatment-related intelligence deficits in children with brain tumours",
abstract = "OBJECTIVE: The Wuerzburger Psychologische Kurz-Diagnostik (WUEP-KD) is a short screening battery for cognitive deficits in children with brain tumour. We report on its psychometric quality and testing efficiency.MATERIAL AND METHODS: WUEP-KD was founded on Cattell-Horn-Carroll (CHC) framework of cognitive abilities. We assessed the construct validity of the short battery by conducting factor analysis and the concurrent validity by multiple linear regressions with Kaufman Assessment Battery for Children (K-ABC). The concurrent validity was explored by multiple linear regressions with Wechsler Intelligence Scale for Children (WISC). The discriminant validity was examined by a reanalysis of harmful effects of brain tumour treatments in a medulloblastoma cohort.RESULTS: The construct validity assessment revealed three neuropsychological domains: cognitive operations, executive abilities, and psychomotor abilities. The retest reliabilities for individual testing and the convergent coefficients of the WUEP-KD with K-ABC and WISC yielded satisfactory results. The cognitive effects of different treatment modalities in the medulloblastoma cohort matched exactly previously reported data on the decline of general intelligence scores and delivered the details for the harmful effects. An in-depth analysis based on Hedges' g effect sizes confirmed specific harmful late effects on all abilities of cognitive operations, on the executive ability of perceptual speed and on psychomotor ability of movement steadiness.CONCLUSION: WUEP-KD is a valid and efficient short test instrument, which may be especially useful in larger cohorts, multicenter settings or if patients do not tolerate longer tests. Due to its foundation on the CHC framework, our findings provide a rationale to create a common data set along with scores from other factor-based tests in international studies.",
keywords = "Adolescent, Brain Neoplasms, Chemoradiotherapy, Child, Cognition Disorders, Factor Analysis, Statistical, Female, Humans, Intelligence Tests, Male, Neuropsychological Tests, Psychometrics",
author = "Holger Ottensmeier and Bernhard Zimolong and Wolff, {Johannes E} and Jochen Ehrich and Niels Galley and {von Hoff}, Katja and Joachim Kuehl and Stefan Rutkowski",
note = "Copyright {\textcopyright} 2015 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.",
year = "2015",
month = may,
doi = "10.1016/j.ejpn.2014.12.019",
language = "English",
volume = "19",
pages = "298--307",
journal = "EUR J PAEDIATR NEURO",
issn = "1090-3798",
publisher = "W.B. Saunders Ltd",
number = "3",

}

RIS

TY - JOUR

T1 - Neuropsychological short assessment of disease- and treatment-related intelligence deficits in children with brain tumours

AU - Ottensmeier, Holger

AU - Zimolong, Bernhard

AU - Wolff, Johannes E

AU - Ehrich, Jochen

AU - Galley, Niels

AU - von Hoff, Katja

AU - Kuehl, Joachim

AU - Rutkowski, Stefan

N1 - Copyright © 2015 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

PY - 2015/5

Y1 - 2015/5

N2 - OBJECTIVE: The Wuerzburger Psychologische Kurz-Diagnostik (WUEP-KD) is a short screening battery for cognitive deficits in children with brain tumour. We report on its psychometric quality and testing efficiency.MATERIAL AND METHODS: WUEP-KD was founded on Cattell-Horn-Carroll (CHC) framework of cognitive abilities. We assessed the construct validity of the short battery by conducting factor analysis and the concurrent validity by multiple linear regressions with Kaufman Assessment Battery for Children (K-ABC). The concurrent validity was explored by multiple linear regressions with Wechsler Intelligence Scale for Children (WISC). The discriminant validity was examined by a reanalysis of harmful effects of brain tumour treatments in a medulloblastoma cohort.RESULTS: The construct validity assessment revealed three neuropsychological domains: cognitive operations, executive abilities, and psychomotor abilities. The retest reliabilities for individual testing and the convergent coefficients of the WUEP-KD with K-ABC and WISC yielded satisfactory results. The cognitive effects of different treatment modalities in the medulloblastoma cohort matched exactly previously reported data on the decline of general intelligence scores and delivered the details for the harmful effects. An in-depth analysis based on Hedges' g effect sizes confirmed specific harmful late effects on all abilities of cognitive operations, on the executive ability of perceptual speed and on psychomotor ability of movement steadiness.CONCLUSION: WUEP-KD is a valid and efficient short test instrument, which may be especially useful in larger cohorts, multicenter settings or if patients do not tolerate longer tests. Due to its foundation on the CHC framework, our findings provide a rationale to create a common data set along with scores from other factor-based tests in international studies.

AB - OBJECTIVE: The Wuerzburger Psychologische Kurz-Diagnostik (WUEP-KD) is a short screening battery for cognitive deficits in children with brain tumour. We report on its psychometric quality and testing efficiency.MATERIAL AND METHODS: WUEP-KD was founded on Cattell-Horn-Carroll (CHC) framework of cognitive abilities. We assessed the construct validity of the short battery by conducting factor analysis and the concurrent validity by multiple linear regressions with Kaufman Assessment Battery for Children (K-ABC). The concurrent validity was explored by multiple linear regressions with Wechsler Intelligence Scale for Children (WISC). The discriminant validity was examined by a reanalysis of harmful effects of brain tumour treatments in a medulloblastoma cohort.RESULTS: The construct validity assessment revealed three neuropsychological domains: cognitive operations, executive abilities, and psychomotor abilities. The retest reliabilities for individual testing and the convergent coefficients of the WUEP-KD with K-ABC and WISC yielded satisfactory results. The cognitive effects of different treatment modalities in the medulloblastoma cohort matched exactly previously reported data on the decline of general intelligence scores and delivered the details for the harmful effects. An in-depth analysis based on Hedges' g effect sizes confirmed specific harmful late effects on all abilities of cognitive operations, on the executive ability of perceptual speed and on psychomotor ability of movement steadiness.CONCLUSION: WUEP-KD is a valid and efficient short test instrument, which may be especially useful in larger cohorts, multicenter settings or if patients do not tolerate longer tests. Due to its foundation on the CHC framework, our findings provide a rationale to create a common data set along with scores from other factor-based tests in international studies.

KW - Adolescent

KW - Brain Neoplasms

KW - Chemoradiotherapy

KW - Child

KW - Cognition Disorders

KW - Factor Analysis, Statistical

KW - Female

KW - Humans

KW - Intelligence Tests

KW - Male

KW - Neuropsychological Tests

KW - Psychometrics

U2 - 10.1016/j.ejpn.2014.12.019

DO - 10.1016/j.ejpn.2014.12.019

M3 - SCORING: Journal article

C2 - 25617910

VL - 19

SP - 298

EP - 307

JO - EUR J PAEDIATR NEURO

JF - EUR J PAEDIATR NEURO

SN - 1090-3798

IS - 3

ER -