Neue Aspekte HPV-positiver Kopf-Hals-Karzinome. Highlights vom ASCO-Kongress 2011
Standard
Neue Aspekte HPV-positiver Kopf-Hals-Karzinome. Highlights vom ASCO-Kongress 2011. / Kofler, B; Uecker, F C; Muenscher, A; Knecht, R.
In: HNO, Vol. 60, No. 5, 05.2012, p. 404-7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Neue Aspekte HPV-positiver Kopf-Hals-Karzinome. Highlights vom ASCO-Kongress 2011
AU - Kofler, B
AU - Uecker, F C
AU - Muenscher, A
AU - Knecht, R
PY - 2012/5
Y1 - 2012/5
N2 - HPV-positive head and neck carcinoma is significantly different than tobacco- and alcohol-induced cancer. Between 30% and 50% of oropharyngeal cancers are associated with human papillomavirus (HPV). Studies still show an increasing incidence. HPV-positive head and neck cancer patients have a better prognosis due to a better response to therapy. Especially patients with gene overexpression of immunological proteins in the antigen presentation are suggested to benefit from radiotherapy. A current retrospective study shows better outcomes for patients treated with radiotherapy in combination with biological targets compared to radiochemotherapy.
AB - HPV-positive head and neck carcinoma is significantly different than tobacco- and alcohol-induced cancer. Between 30% and 50% of oropharyngeal cancers are associated with human papillomavirus (HPV). Studies still show an increasing incidence. HPV-positive head and neck cancer patients have a better prognosis due to a better response to therapy. Especially patients with gene overexpression of immunological proteins in the antigen presentation are suggested to benefit from radiotherapy. A current retrospective study shows better outcomes for patients treated with radiotherapy in combination with biological targets compared to radiochemotherapy.
KW - Chemoradiotherapy
KW - Evidence-Based Medicine
KW - Head and Neck Neoplasms
KW - Humans
KW - Molecular Targeted Therapy
KW - Papillomaviridae
U2 - 10.1007/s00106-011-2465-y
DO - 10.1007/s00106-011-2465-y
M3 - SCORING: Zeitschriftenaufsatz
C2 - 22570004
VL - 60
SP - 404
EP - 407
JO - HNO
JF - HNO
SN - 0017-6192
IS - 5
ER -