Necessity of epicardial ablation for ventricular tachycardia after sequential endocardial approach
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Necessity of epicardial ablation for ventricular tachycardia after sequential endocardial approach. / Sultan, Arian; Lüker, Jakob; Hoffmann, Boris; Servatius, Helge; Aydin, Ali; Nührich, Jana; Akbulak, Özge; Schreiber, Doreen; Schäffer, Benjamin; Rostock, Thomas; Willems, Stephan; Steven, Daniel.
In: INT J CARDIOL, Vol. 182, 01.03.2015, p. 56-61.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Necessity of epicardial ablation for ventricular tachycardia after sequential endocardial approach
AU - Sultan, Arian
AU - Lüker, Jakob
AU - Hoffmann, Boris
AU - Servatius, Helge
AU - Aydin, Ali
AU - Nührich, Jana
AU - Akbulak, Özge
AU - Schreiber, Doreen
AU - Schäffer, Benjamin
AU - Rostock, Thomas
AU - Willems, Stephan
AU - Steven, Daniel
N1 - Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
PY - 2015/3/1
Y1 - 2015/3/1
N2 - BACKGROUND: Catheter ablation (CA) of ventricular tachycardia (VT) is an important treatment option in patients with structural heart disease (SHD) and implantable cardioverter defibrillator (ICD). A subset of patients requires epicardial CA for VT.OBJECTIVE: The purpose of the study was to assess the significance of epicardial CA in these patients after a systematic sequential endocardial approach.METHODS: Between January 2009 and October 2012 CA for VT was analyzed. A sequential CA approach guided by earliest ventricular activation, pacemap, entrainment and stimulus to QRS-interval analysis was used. Acute CA success was assessed by programmed ventricular stimulation. ICD interrogation and 24h-Holter ECG were used to evaluate long-term success.RESULTS: One hundred sixty VT ablation procedures in 126 consecutive patients (114 men; age 65±12years) were performed. Endocardial CA succeeded in 250 (94%) out of 265 treated VT. For 15 (6%) VT an additional epicardial CA was performed and succeeded in 9 of these 15 VT. Long-term FU (25±18.2month) showed freedom of VT in 104 pts (82%) after 1.2±0.5 procedures, 11 (9%) suffered from repeated ICD shocks and 11 (9%) died due to worsening of heart failure.CONCLUSIONS: Despite a heterogenic substrate for VT in SHD, endocardial CA alone results in high acute success rates. In this study additional epicardial CA following a sequential endocardial mapping and CA approach was performed in 6% of VT. Thus, due to possible complications epicardial CA should only be considered if endocardial CA fails.
AB - BACKGROUND: Catheter ablation (CA) of ventricular tachycardia (VT) is an important treatment option in patients with structural heart disease (SHD) and implantable cardioverter defibrillator (ICD). A subset of patients requires epicardial CA for VT.OBJECTIVE: The purpose of the study was to assess the significance of epicardial CA in these patients after a systematic sequential endocardial approach.METHODS: Between January 2009 and October 2012 CA for VT was analyzed. A sequential CA approach guided by earliest ventricular activation, pacemap, entrainment and stimulus to QRS-interval analysis was used. Acute CA success was assessed by programmed ventricular stimulation. ICD interrogation and 24h-Holter ECG were used to evaluate long-term success.RESULTS: One hundred sixty VT ablation procedures in 126 consecutive patients (114 men; age 65±12years) were performed. Endocardial CA succeeded in 250 (94%) out of 265 treated VT. For 15 (6%) VT an additional epicardial CA was performed and succeeded in 9 of these 15 VT. Long-term FU (25±18.2month) showed freedom of VT in 104 pts (82%) after 1.2±0.5 procedures, 11 (9%) suffered from repeated ICD shocks and 11 (9%) died due to worsening of heart failure.CONCLUSIONS: Despite a heterogenic substrate for VT in SHD, endocardial CA alone results in high acute success rates. In this study additional epicardial CA following a sequential endocardial mapping and CA approach was performed in 6% of VT. Thus, due to possible complications epicardial CA should only be considered if endocardial CA fails.
KW - Aged
KW - Catheter Ablation/methods
KW - Endocardium/surgery
KW - Female
KW - Follow-Up Studies
KW - Heart Conduction System/physiopathology
KW - Heart Rate/physiology
KW - Humans
KW - Male
KW - Pericardium/surgery
KW - Recurrence
KW - Reoperation
KW - Retrospective Studies
KW - Tachycardia, Ventricular/physiopathology
KW - Treatment Outcome
U2 - 10.1016/j.ijcard.2014.12.003
DO - 10.1016/j.ijcard.2014.12.003
M3 - SCORING: Journal article
C2 - 25576719
VL - 182
SP - 56
EP - 61
JO - INT J CARDIOL
JF - INT J CARDIOL
SN - 0167-5273
ER -