National screening program vs. standardized neurodevelopmental follow-up.
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National screening program vs. standardized neurodevelopmental follow-up. / Maschke, Cornelia; Ellenrieder, Birte; Hecher, Kurt; Bartmann, Peter.
In: J PERINAT MED, Vol. 37, No. 1, 1, 2009, p. 87-90.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - National screening program vs. standardized neurodevelopmental follow-up.
AU - Maschke, Cornelia
AU - Ellenrieder, Birte
AU - Hecher, Kurt
AU - Bartmann, Peter
PY - 2009
Y1 - 2009
N2 - BACKGROUND: Long-term follow-up is urgently needed to decide on the consequences of new therapies. OBJECTIVE: This study assesses the use of a national child development screening program for a follow-up examination of a defined patient group. PATIENTS AND METHODS: Neurodevelopmental outcome of 139 survivors after intrauterine laser coagulation for severe twin-twin transfusion syndrome was investigated both according to a standardized neurodevelopmental follow-up and according to the pediatricians' screening examinations. RESULTS: Screening and standardized tests revealed identical results in 90.6% of the cases. Using the national screening program only four out of 139 children (2.9%) with minor neurological disabilities would have been missed. For identifying mild or severe neurodevelopmental abnormalities the screening has a sensitivity of 78% and a specificity of 93%. The positive predictive value is 61% and the negative predictive value 97%. CONCLUSIONS: The use of already available and established follow-up programs for extended follow-up studies would considerably reduce costs, time and manpower.
AB - BACKGROUND: Long-term follow-up is urgently needed to decide on the consequences of new therapies. OBJECTIVE: This study assesses the use of a national child development screening program for a follow-up examination of a defined patient group. PATIENTS AND METHODS: Neurodevelopmental outcome of 139 survivors after intrauterine laser coagulation for severe twin-twin transfusion syndrome was investigated both according to a standardized neurodevelopmental follow-up and according to the pediatricians' screening examinations. RESULTS: Screening and standardized tests revealed identical results in 90.6% of the cases. Using the national screening program only four out of 139 children (2.9%) with minor neurological disabilities would have been missed. For identifying mild or severe neurodevelopmental abnormalities the screening has a sensitivity of 78% and a specificity of 93%. The positive predictive value is 61% and the negative predictive value 97%. CONCLUSIONS: The use of already available and established follow-up programs for extended follow-up studies would considerably reduce costs, time and manpower.
M3 - SCORING: Zeitschriftenaufsatz
VL - 37
SP - 87
EP - 90
JO - J PERINAT MED
JF - J PERINAT MED
SN - 0300-5577
IS - 1
M1 - 1
ER -
