Nail Assessment in Psoriasis and Psoriatic Arthritis (NAPPA): development and validation of a tool for assessment of nail psoriasis outcomes
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Nail Assessment in Psoriasis and Psoriatic Arthritis (NAPPA): development and validation of a tool for assessment of nail psoriasis outcomes. / Augustin, M; Blome, C; Costanzo, A; Dauden, E; Ferrandiz, C; Girolomoni, G; Gniadecki, R; Iversen, L; Menter, A; Michaelis-Wittern, K; Morita, A; Nakagawa, H; Reich, K.
In: BRIT J DERMATOL, Vol. 170, No. 3, 01.03.2014, p. 591-8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Nail Assessment in Psoriasis and Psoriatic Arthritis (NAPPA): development and validation of a tool for assessment of nail psoriasis outcomes
AU - Augustin, M
AU - Blome, C
AU - Costanzo, A
AU - Dauden, E
AU - Ferrandiz, C
AU - Girolomoni, G
AU - Gniadecki, R
AU - Iversen, L
AU - Menter, A
AU - Michaelis-Wittern, K
AU - Morita, A
AU - Nakagawa, H
AU - Reich, K
N1 - © 2013 British Association of Dermatologists.
PY - 2014/3/1
Y1 - 2014/3/1
N2 - BACKGROUND: Existing tools for nail psoriasis are complex and may not adequately measure outcomes that are important to patients.OBJECTIVES: We have developed and validated a new tool, the Nail Assessment in Psoriasis and Psoriatic Arthritis (NAPPA), with three components: a questionnaire assessing quality of life (NAPPA-QoL), a two-part questionnaire assessing patient-relevant treatment benefits (the Patient Benefit Index, NAPPA-PBI) and a psoriasis Clinical Assessment of Severity (NAPPA-CLIN).METHODS: Development of the questionnaires involved multiple steps: (i) collection of items about nail psoriasis-related impairments and treatment goals; (ii) selection of 48 items by an expert panel, including patients; (iii) translation into eight languages; (iv) feasibility testing and (v) longitudinal validation in six countries.RESULTS: Patients found the questionnaires clear (84%) and comprehensible (95%). NAPPA-QoL and NAPPA-PBI scores correlated moderately with clinical outcomes [e.g. Nail Psoriasis Severity Index (NAPSI)] and markedly with other quality-of-life questionnaires (e.g. EQ-5D™). Both questionnaires were sensitive to change. Internal consistency was good (Cronbach α ≥ 0.88 for all scales). The NAPPA-CLIN, a brief version of NAPSI that involves assessment of only four digits rather than all 20, was found to correlate highly with total NAPSI score (r = 0.97, P < 0.001).CONCLUSIONS: Overall, the three-component NAPPA tool is a valid, reliable and practical instrument to assess patient-relevant nail psoriasis outcomes.
AB - BACKGROUND: Existing tools for nail psoriasis are complex and may not adequately measure outcomes that are important to patients.OBJECTIVES: We have developed and validated a new tool, the Nail Assessment in Psoriasis and Psoriatic Arthritis (NAPPA), with three components: a questionnaire assessing quality of life (NAPPA-QoL), a two-part questionnaire assessing patient-relevant treatment benefits (the Patient Benefit Index, NAPPA-PBI) and a psoriasis Clinical Assessment of Severity (NAPPA-CLIN).METHODS: Development of the questionnaires involved multiple steps: (i) collection of items about nail psoriasis-related impairments and treatment goals; (ii) selection of 48 items by an expert panel, including patients; (iii) translation into eight languages; (iv) feasibility testing and (v) longitudinal validation in six countries.RESULTS: Patients found the questionnaires clear (84%) and comprehensible (95%). NAPPA-QoL and NAPPA-PBI scores correlated moderately with clinical outcomes [e.g. Nail Psoriasis Severity Index (NAPSI)] and markedly with other quality-of-life questionnaires (e.g. EQ-5D™). Both questionnaires were sensitive to change. Internal consistency was good (Cronbach α ≥ 0.88 for all scales). The NAPPA-CLIN, a brief version of NAPSI that involves assessment of only four digits rather than all 20, was found to correlate highly with total NAPSI score (r = 0.97, P < 0.001).CONCLUSIONS: Overall, the three-component NAPPA tool is a valid, reliable and practical instrument to assess patient-relevant nail psoriasis outcomes.
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Arthritis, Psoriatic
KW - Feasibility Studies
KW - Female
KW - Humans
KW - Male
KW - Middle Aged
KW - Nail Diseases
KW - Patient Outcome Assessment
KW - Patient Satisfaction
KW - Psoriasis
KW - Quality of Life
KW - Treatment Outcome
KW - Young Adult
U2 - 10.1111/bjd.12664
DO - 10.1111/bjd.12664
M3 - SCORING: Journal article
C2 - 24117393
VL - 170
SP - 591
EP - 598
JO - BRIT J DERMATOL
JF - BRIT J DERMATOL
SN - 0007-0963
IS - 3
ER -