Myocardial infarction incidence and ischemic heart disease mortality: overall and trend results in repatriates, Germany

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Myocardial infarction incidence and ischemic heart disease mortality: overall and trend results in repatriates, Germany. / Deckert, Andreas; Winkler, Volker; Meisinger, Christa; Heier, Margit; Becher, Heiko.

In: EUR J PUBLIC HEALTH, Vol. 24, No. 1, 2014, p. 127-133.

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@article{1d31ad9546df4150bab4728c5b708eb7,
title = "Myocardial infarction incidence and ischemic heart disease mortality: overall and trend results in repatriates, Germany",
abstract = "BACKGROUND: The burden of cardiovascular diseases (CVDs) is much more pronounced in Eastern Europe, a spatial gradient within Europe still exists. However, former studies showed a significantly lower CVD mortality of German repatriates from the Former Soviet Union compared with the German population.METHODS: All-cause, CVD and ischemic heart disease (IHD) standardized mortality ratio (SMR), IHD standardized incidence ratio and annual age-standardized mortality and acute myocardial infarction (AMI) incidence rates were calculated in a retrospective cohort. Time trends were investigated by loess regression.RESULTS: A total of 6378 German repatriates were observed from 1990 to 2010, accumulating 92 149 person-years. We observed a lower all-cause mortality [SMR = 0.86 (0.75, 0.98)] in females and CVD mortality [International Statistical Classification of Diseases and Related Health Problems, version 10 (ICD) 10: I00-I99; SMR = 0.82 (0.65, 1.03)] and IHD mortality (I20-I25) [SMR = 0.84 (0.60, 1.15)] in males. In contrast, AMI incidence was significantly higher in male repatriates [standardized incidence ratio = 1.30 (1.02, 1.65)]. Whereas in the general population, mortality rates of CVD, IHD and AMI incidence have continuously decreased over time, the pattern in the repatriates was not as clear. In male repatriates, mortality rates seemed to be lower after immigration and remained rather constant. Incidence rates possibly exceed Germans rates by now.CONCLUSIONS: A possible historical repatriates' IHD advantage shown in former studies has disappeared. The increasing AMI incidence in (male) repatriates might demonstrate the delaying onset of the impact of changes in the CVD risk profile due to migration. Health politics and the health system should be sensitized and take care of the development of IHD mortality and AMI incidence among the repatriates.",
keywords = "Adult, Age Factors, Aged, Female, Germany, Humans, Incidence, Male, Middle Aged, Myocardial Infarction, Myocardial Ischemia, Retrospective Studies, Risk Factors, Sex Factors, USSR",
author = "Andreas Deckert and Volker Winkler and Christa Meisinger and Margit Heier and Heiko Becher",
year = "2014",
doi = "10.1093/eurpub/ckt058",
language = "English",
volume = "24",
pages = "127--133",
journal = "EUR J PUBLIC HEALTH",
issn = "1101-1262",
publisher = "Oxford University Press",
number = "1",

}

RIS

TY - JOUR

T1 - Myocardial infarction incidence and ischemic heart disease mortality: overall and trend results in repatriates, Germany

AU - Deckert, Andreas

AU - Winkler, Volker

AU - Meisinger, Christa

AU - Heier, Margit

AU - Becher, Heiko

PY - 2014

Y1 - 2014

N2 - BACKGROUND: The burden of cardiovascular diseases (CVDs) is much more pronounced in Eastern Europe, a spatial gradient within Europe still exists. However, former studies showed a significantly lower CVD mortality of German repatriates from the Former Soviet Union compared with the German population.METHODS: All-cause, CVD and ischemic heart disease (IHD) standardized mortality ratio (SMR), IHD standardized incidence ratio and annual age-standardized mortality and acute myocardial infarction (AMI) incidence rates were calculated in a retrospective cohort. Time trends were investigated by loess regression.RESULTS: A total of 6378 German repatriates were observed from 1990 to 2010, accumulating 92 149 person-years. We observed a lower all-cause mortality [SMR = 0.86 (0.75, 0.98)] in females and CVD mortality [International Statistical Classification of Diseases and Related Health Problems, version 10 (ICD) 10: I00-I99; SMR = 0.82 (0.65, 1.03)] and IHD mortality (I20-I25) [SMR = 0.84 (0.60, 1.15)] in males. In contrast, AMI incidence was significantly higher in male repatriates [standardized incidence ratio = 1.30 (1.02, 1.65)]. Whereas in the general population, mortality rates of CVD, IHD and AMI incidence have continuously decreased over time, the pattern in the repatriates was not as clear. In male repatriates, mortality rates seemed to be lower after immigration and remained rather constant. Incidence rates possibly exceed Germans rates by now.CONCLUSIONS: A possible historical repatriates' IHD advantage shown in former studies has disappeared. The increasing AMI incidence in (male) repatriates might demonstrate the delaying onset of the impact of changes in the CVD risk profile due to migration. Health politics and the health system should be sensitized and take care of the development of IHD mortality and AMI incidence among the repatriates.

AB - BACKGROUND: The burden of cardiovascular diseases (CVDs) is much more pronounced in Eastern Europe, a spatial gradient within Europe still exists. However, former studies showed a significantly lower CVD mortality of German repatriates from the Former Soviet Union compared with the German population.METHODS: All-cause, CVD and ischemic heart disease (IHD) standardized mortality ratio (SMR), IHD standardized incidence ratio and annual age-standardized mortality and acute myocardial infarction (AMI) incidence rates were calculated in a retrospective cohort. Time trends were investigated by loess regression.RESULTS: A total of 6378 German repatriates were observed from 1990 to 2010, accumulating 92 149 person-years. We observed a lower all-cause mortality [SMR = 0.86 (0.75, 0.98)] in females and CVD mortality [International Statistical Classification of Diseases and Related Health Problems, version 10 (ICD) 10: I00-I99; SMR = 0.82 (0.65, 1.03)] and IHD mortality (I20-I25) [SMR = 0.84 (0.60, 1.15)] in males. In contrast, AMI incidence was significantly higher in male repatriates [standardized incidence ratio = 1.30 (1.02, 1.65)]. Whereas in the general population, mortality rates of CVD, IHD and AMI incidence have continuously decreased over time, the pattern in the repatriates was not as clear. In male repatriates, mortality rates seemed to be lower after immigration and remained rather constant. Incidence rates possibly exceed Germans rates by now.CONCLUSIONS: A possible historical repatriates' IHD advantage shown in former studies has disappeared. The increasing AMI incidence in (male) repatriates might demonstrate the delaying onset of the impact of changes in the CVD risk profile due to migration. Health politics and the health system should be sensitized and take care of the development of IHD mortality and AMI incidence among the repatriates.

KW - Adult

KW - Age Factors

KW - Aged

KW - Female

KW - Germany

KW - Humans

KW - Incidence

KW - Male

KW - Middle Aged

KW - Myocardial Infarction

KW - Myocardial Ischemia

KW - Retrospective Studies

KW - Risk Factors

KW - Sex Factors

KW - USSR

U2 - 10.1093/eurpub/ckt058

DO - 10.1093/eurpub/ckt058

M3 - SCORING: Journal article

C2 - 23729483

VL - 24

SP - 127

EP - 133

JO - EUR J PUBLIC HEALTH

JF - EUR J PUBLIC HEALTH

SN - 1101-1262

IS - 1

ER -