Myocardial contractile response to increasing doses of dobutamine in patients with reperfused acute myocardial infarction by cardiac magnetic resonance imaging.

  • Achim Barmeyer
  • Alexander Stork
  • Paul Martin Bansmann
  • Kai Müllerleile
  • Marcus Bavastro
  • Mirko Heuer
  • Gerhard Adam
  • Thomas Meinertz
  • Gunnar Lund

Abstract

BACKGROUND: Cardiac magnetic resonance imaging uses contractile response to dobutamine (DCMR) and delayed contrast enhancement (DE) to assess myocardial viability. However, early after acute myocardial infarction (AMI) the optimal dose of dobutamine is unclear. METHODS: In patients early after reperfused AMI, DCMR at 5, 10 and 20 microg*kg(-1)*min(-1) and measurement of DE was performed. On three short-axis slices 18 segments were graded as no DE, DE or=50%. Thickening (systolic-diastolic wall thickness) and contractile reserve (max. thickening - rest) were determined. Segments were classified dysfunctional if thickening was >2 SD below normal or

Bibliographical data

Original languageGerman
Article number3
ISSN0008-6312
Publication statusPublished - 2008
pubmed 18057882