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Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis.

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Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis. / Hov, Johannes R; Keitel, Verena; Laerdahl, Jon K; Spomer, Lina; Ellinghaus, Eva; ElSharawy, Abdou; Melum, Espen; Boberg, Kirsten M; Manke, Thomas; Balschun, Tobias; Schramm, Christoph; Bergquist, Annika; Weismüller, Tobias; Gotthardt, Daniel; Rust, Christian; Henckaerts, Liesbet; Onnie, Clive M; Weersma, Rinse K; Sterneck, Martina; Teufel, Andreas; Runz, Heiko; Stiehl, Adolf; Ponsioen, Cyriel Y; Wijmenga, Cisca; Vatn, Morten H; Stokkers, Pieter C F; Vermeire, Severine; Mathew, Christopher G; Lie, Benedicte A; Beuers, Ulrich; Manns, Michael P; Schreiber, Stefan; Schrumpf, Erik; Häussinger, Dieter; Franke, Andre; Karlsen, Tom H.

In: PLOS ONE, Vol. 5, No. 8, 8, 2010, p. 12403.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Hov, JR, Keitel, V, Laerdahl, JK, Spomer, L, Ellinghaus, E, ElSharawy, A, Melum, E, Boberg, KM, Manke, T, Balschun, T, Schramm, C, Bergquist, A, Weismüller, T, Gotthardt, D, Rust, C, Henckaerts, L, Onnie, CM, Weersma, RK, Sterneck, M, Teufel, A, Runz, H, Stiehl, A, Ponsioen, CY, Wijmenga, C, Vatn, MH, Stokkers, PCF, Vermeire, S, Mathew, CG, Lie, BA, Beuers, U, Manns, MP, Schreiber, S, Schrumpf, E, Häussinger, D, Franke, A & Karlsen, TH 2010, 'Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis.', PLOS ONE, vol. 5, no. 8, 8, pp. 12403. https://doi.org/10.1371/journal.pone.0012403

APA

Hov, J. R., Keitel, V., Laerdahl, J. K., Spomer, L., Ellinghaus, E., ElSharawy, A., Melum, E., Boberg, K. M., Manke, T., Balschun, T., Schramm, C., Bergquist, A., Weismüller, T., Gotthardt, D., Rust, C., Henckaerts, L., Onnie, C. M., Weersma, R. K., Sterneck, M., ... Karlsen, T. H. (2010). Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis. PLOS ONE, 5(8), 12403. [8]. https://doi.org/10.1371/journal.pone.0012403

Vancouver

Hov JR, Keitel V, Laerdahl JK, Spomer L, Ellinghaus E, ElSharawy A et al. Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis. PLOS ONE. 2010;5(8):12403. 8. https://doi.org/10.1371/journal.pone.0012403

Bibtex

@article{f7e7b1fe0ee34599ade6edbe2237442d,
title = "Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis.",
abstract = "TGR5, the G protein-coupled bile acid receptor 1 (GPBAR1), has been linked to inflammatory pathways as well as bile homeostasis, and could therefore be involved in primary sclerosing cholangitis (PSC) a chronic inflammatory bile duct disease. We aimed to extensively investigate TGR5 sequence variation in PSC, as well as functionally characterize detected variants.",
author = "Hov, {Johannes R} and Verena Keitel and Laerdahl, {Jon K} and Lina Spomer and Eva Ellinghaus and Abdou ElSharawy and Espen Melum and Boberg, {Kirsten M} and Thomas Manke and Tobias Balschun and Christoph Schramm and Annika Bergquist and Tobias Weism{\"u}ller and Daniel Gotthardt and Christian Rust and Liesbet Henckaerts and Onnie, {Clive M} and Weersma, {Rinse K} and Martina Sterneck and Andreas Teufel and Heiko Runz and Adolf Stiehl and Ponsioen, {Cyriel Y} and Cisca Wijmenga and Vatn, {Morten H} and Stokkers, {Pieter C F} and Severine Vermeire and Mathew, {Christopher G} and Lie, {Benedicte A} and Ulrich Beuers and Manns, {Michael P} and Stefan Schreiber and Erik Schrumpf and Dieter H{\"a}ussinger and Andre Franke and Karlsen, {Tom H}",
year = "2010",
doi = "10.1371/journal.pone.0012403",
language = "Deutsch",
volume = "5",
pages = "12403",
journal = "PLOS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "8",

}

RIS

TY - JOUR

T1 - Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis.

AU - Hov, Johannes R

AU - Keitel, Verena

AU - Laerdahl, Jon K

AU - Spomer, Lina

AU - Ellinghaus, Eva

AU - ElSharawy, Abdou

AU - Melum, Espen

AU - Boberg, Kirsten M

AU - Manke, Thomas

AU - Balschun, Tobias

AU - Schramm, Christoph

AU - Bergquist, Annika

AU - Weismüller, Tobias

AU - Gotthardt, Daniel

AU - Rust, Christian

AU - Henckaerts, Liesbet

AU - Onnie, Clive M

AU - Weersma, Rinse K

AU - Sterneck, Martina

AU - Teufel, Andreas

AU - Runz, Heiko

AU - Stiehl, Adolf

AU - Ponsioen, Cyriel Y

AU - Wijmenga, Cisca

AU - Vatn, Morten H

AU - Stokkers, Pieter C F

AU - Vermeire, Severine

AU - Mathew, Christopher G

AU - Lie, Benedicte A

AU - Beuers, Ulrich

AU - Manns, Michael P

AU - Schreiber, Stefan

AU - Schrumpf, Erik

AU - Häussinger, Dieter

AU - Franke, Andre

AU - Karlsen, Tom H

PY - 2010

Y1 - 2010

N2 - TGR5, the G protein-coupled bile acid receptor 1 (GPBAR1), has been linked to inflammatory pathways as well as bile homeostasis, and could therefore be involved in primary sclerosing cholangitis (PSC) a chronic inflammatory bile duct disease. We aimed to extensively investigate TGR5 sequence variation in PSC, as well as functionally characterize detected variants.

AB - TGR5, the G protein-coupled bile acid receptor 1 (GPBAR1), has been linked to inflammatory pathways as well as bile homeostasis, and could therefore be involved in primary sclerosing cholangitis (PSC) a chronic inflammatory bile duct disease. We aimed to extensively investigate TGR5 sequence variation in PSC, as well as functionally characterize detected variants.

U2 - 10.1371/journal.pone.0012403

DO - 10.1371/journal.pone.0012403

M3 - SCORING: Zeitschriftenaufsatz

VL - 5

SP - 12403

JO - PLOS ONE

JF - PLOS ONE

SN - 1932-6203

IS - 8

M1 - 8

ER -