Multisite Thrombosis in a Patient with Paroxysmal Nocturnal Hemoglobinuria

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Multisite Thrombosis in a Patient with Paroxysmal Nocturnal Hemoglobinuria. / Beckmann, Lennart; Faizy, Tobias; Flottmann, Fabian Alexander; Fiehler, Jens; Bokemeyer, Carsten; Well, Lennart; Beitzen-Heineke, Antonia; Langer, Florian.

In: HAMOSTASEOLOGIE, 09.02.2024.

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@article{7e65a396d3504eb091255350b961c6a3,
title = "Multisite Thrombosis in a Patient with Paroxysmal Nocturnal Hemoglobinuria",
abstract = "Paroxysmal nocturnal hemoglobinuria (PNH) is an extremely rare bone marrow disorder caused by acquired mutations in the phosphatidylinositol glycan class A gene, which lead to a partial or total loss of the cellular complement regulators CD55 and CD59.1 In addition to complement-mediated hemolysis and cytopenia, venous and arterial thromboses at multiple and/or unusual sites are a common complication and occur in up to 44% of patients in historic PNH cohorts.1 2.",
author = "Lennart Beckmann and Tobias Faizy and Flottmann, {Fabian Alexander} and Jens Fiehler and Carsten Bokemeyer and Lennart Well and Antonia Beitzen-Heineke and Florian Langer",
year = "2024",
month = feb,
day = "9",
doi = "10.1055/a-2231-5277",
language = "English",
journal = "HAMOSTASEOLOGIE",
issn = "0720-9355",
publisher = "Schattauer",

}

RIS

TY - JOUR

T1 - Multisite Thrombosis in a Patient with Paroxysmal Nocturnal Hemoglobinuria

AU - Beckmann, Lennart

AU - Faizy, Tobias

AU - Flottmann, Fabian Alexander

AU - Fiehler, Jens

AU - Bokemeyer, Carsten

AU - Well, Lennart

AU - Beitzen-Heineke, Antonia

AU - Langer, Florian

PY - 2024/2/9

Y1 - 2024/2/9

N2 - Paroxysmal nocturnal hemoglobinuria (PNH) is an extremely rare bone marrow disorder caused by acquired mutations in the phosphatidylinositol glycan class A gene, which lead to a partial or total loss of the cellular complement regulators CD55 and CD59.1 In addition to complement-mediated hemolysis and cytopenia, venous and arterial thromboses at multiple and/or unusual sites are a common complication and occur in up to 44% of patients in historic PNH cohorts.1 2.

AB - Paroxysmal nocturnal hemoglobinuria (PNH) is an extremely rare bone marrow disorder caused by acquired mutations in the phosphatidylinositol glycan class A gene, which lead to a partial or total loss of the cellular complement regulators CD55 and CD59.1 In addition to complement-mediated hemolysis and cytopenia, venous and arterial thromboses at multiple and/or unusual sites are a common complication and occur in up to 44% of patients in historic PNH cohorts.1 2.

U2 - 10.1055/a-2231-5277

DO - 10.1055/a-2231-5277

M3 - Short publication

C2 - 38335997

JO - HAMOSTASEOLOGIE

JF - HAMOSTASEOLOGIE

SN - 0720-9355

ER -