Multiresistente Erreger – Sind sie auch resistent gegenüber Desinfektionsmitteln?
Standard
Multiresistente Erreger – Sind sie auch resistent gegenüber Desinfektionsmitteln? / Knobloch, Johannes; Knobling, Birte.
In: DEUT MED WOCHENSCHR, Vol. 149, No. 19, 09.2024, p. 1151-1157.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Multiresistente Erreger – Sind sie auch resistent gegenüber Desinfektionsmitteln?
AU - Knobloch, Johannes
AU - Knobling, Birte
N1 - Thieme. All rights reserved.
PY - 2024/9
Y1 - 2024/9
N2 - Epidemiological studies show that the care of patients in rooms with a previous stay by a person with evidence of multi-resistant pathogens (MRP) is associated with an increased risk of these pathogens occurring. The question therefore regularly arises as to whether MRP also exhibit resistance to the disinfectants used. To date, there are no standardised definitions for "resistance" to disinfectants. However, disinfectants authorised on the market are also effective against multi-resistant pathogens and the failure of efficient disinfection is mainly caused by application errors (insufficient cleaning, incomplete wetting, incorrect application concentration or exposure time etc.). The effectiveness of disinfectants depends on a variety of environmental factors (especially accompanying contamination). A reduced sensitivity to disinfectants can occur in individual isolates due to selection under sub-inhibitory concentrations of disinfectants. Resistance mechanisms to antibiotics do not mediate cross-resistance to disinfectants, but a change in the permeability of bacterial cells can influence sensitivity to disinfectants and antibiotics. In general, the success of routine disinfection can be improved by suitable process controls and contribute to reducing the transmission of MRP.
AB - Epidemiological studies show that the care of patients in rooms with a previous stay by a person with evidence of multi-resistant pathogens (MRP) is associated with an increased risk of these pathogens occurring. The question therefore regularly arises as to whether MRP also exhibit resistance to the disinfectants used. To date, there are no standardised definitions for "resistance" to disinfectants. However, disinfectants authorised on the market are also effective against multi-resistant pathogens and the failure of efficient disinfection is mainly caused by application errors (insufficient cleaning, incomplete wetting, incorrect application concentration or exposure time etc.). The effectiveness of disinfectants depends on a variety of environmental factors (especially accompanying contamination). A reduced sensitivity to disinfectants can occur in individual isolates due to selection under sub-inhibitory concentrations of disinfectants. Resistance mechanisms to antibiotics do not mediate cross-resistance to disinfectants, but a change in the permeability of bacterial cells can influence sensitivity to disinfectants and antibiotics. In general, the success of routine disinfection can be improved by suitable process controls and contribute to reducing the transmission of MRP.
KW - Disinfectants/pharmacology
KW - Humans
KW - Disinfection/methods
KW - Cross Infection/prevention & control
KW - Drug Resistance, Multiple, Bacterial
U2 - 10.1055/a-2250-0901
DO - 10.1055/a-2250-0901
M3 - SCORING: Review
C2 - 39250953
VL - 149
SP - 1151
EP - 1157
JO - DEUT MED WOCHENSCHR
JF - DEUT MED WOCHENSCHR
SN - 0012-0472
IS - 19
ER -