Multiple Evanescent White Dot Syndrome (MEWDS) Associated with Progression of Lacquer Cracks in High Myopia

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Multiple Evanescent White Dot Syndrome (MEWDS) Associated with Progression of Lacquer Cracks in High Myopia. / Ong, Ariel Yuhan; Birtel, Johannes; Charbel Issa, Peter.

In: KLIN MONATSBL AUGENH, Vol. 238, No. 10, 10.2021, p. 1098-1100.

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@article{0e005e4fc4a24079ab25357b7e21cbe5,
title = "Multiple Evanescent White Dot Syndrome (MEWDS) Associated with Progression of Lacquer Cracks in High Myopia",
abstract = "PURPOSE: To report a case of multiple evanescent white dot syndrome (MEWDS) associated with acute progression of lacquer cracks in high myopia.CASE REPORT: A 41-year-old female patient with high myopia developed typical signs, symptoms, and disease course of MEWDS in her right eye. At the same time, the same eye showed progression of lacquer cracks when compared to images taken 2 months prior. Retinal imaging findings characteristic of MEWDS were most obvious on fundus autofluorescence, whereas alterations on color fundus photography, optical coherence tomography, fluorescein, and indocyanine green angiography were very mild, probably because of the myopia-related fundus pathology.CONCLUSION: We present a case of MEWDS co-occurring with acute progression of lacquer cracks. This adds to the increasing evidence that impaired integrity of the retinal pigment epithelium-Bruch's membrane complex may be a factor in causing MEWDS, possibly by exposing otherwise isolated antigens. The anatomy in a highly myopic eye may make it challenging to diagnose MEWDS-associated fundus changes.",
keywords = "Adult, Female, Fluorescein Angiography, Fundus Oculi, Humans, Lacquer, Myopia/complications, Retinal Diseases/diagnosis, Tomography, Optical Coherence, White Dot Syndromes",
author = "Ong, {Ariel Yuhan} and Johannes Birtel and {Charbel Issa}, Peter",
note = "Thieme. All rights reserved.",
year = "2021",
month = oct,
doi = "10.1055/a-1515-6065",
language = "English",
volume = "238",
pages = "1098--1100",
journal = "KLIN MONATSBL AUGENH",
issn = "0023-2165",
publisher = "Ferdinand Enke Verlag",
number = "10",

}

RIS

TY - JOUR

T1 - Multiple Evanescent White Dot Syndrome (MEWDS) Associated with Progression of Lacquer Cracks in High Myopia

AU - Ong, Ariel Yuhan

AU - Birtel, Johannes

AU - Charbel Issa, Peter

N1 - Thieme. All rights reserved.

PY - 2021/10

Y1 - 2021/10

N2 - PURPOSE: To report a case of multiple evanescent white dot syndrome (MEWDS) associated with acute progression of lacquer cracks in high myopia.CASE REPORT: A 41-year-old female patient with high myopia developed typical signs, symptoms, and disease course of MEWDS in her right eye. At the same time, the same eye showed progression of lacquer cracks when compared to images taken 2 months prior. Retinal imaging findings characteristic of MEWDS were most obvious on fundus autofluorescence, whereas alterations on color fundus photography, optical coherence tomography, fluorescein, and indocyanine green angiography were very mild, probably because of the myopia-related fundus pathology.CONCLUSION: We present a case of MEWDS co-occurring with acute progression of lacquer cracks. This adds to the increasing evidence that impaired integrity of the retinal pigment epithelium-Bruch's membrane complex may be a factor in causing MEWDS, possibly by exposing otherwise isolated antigens. The anatomy in a highly myopic eye may make it challenging to diagnose MEWDS-associated fundus changes.

AB - PURPOSE: To report a case of multiple evanescent white dot syndrome (MEWDS) associated with acute progression of lacquer cracks in high myopia.CASE REPORT: A 41-year-old female patient with high myopia developed typical signs, symptoms, and disease course of MEWDS in her right eye. At the same time, the same eye showed progression of lacquer cracks when compared to images taken 2 months prior. Retinal imaging findings characteristic of MEWDS were most obvious on fundus autofluorescence, whereas alterations on color fundus photography, optical coherence tomography, fluorescein, and indocyanine green angiography were very mild, probably because of the myopia-related fundus pathology.CONCLUSION: We present a case of MEWDS co-occurring with acute progression of lacquer cracks. This adds to the increasing evidence that impaired integrity of the retinal pigment epithelium-Bruch's membrane complex may be a factor in causing MEWDS, possibly by exposing otherwise isolated antigens. The anatomy in a highly myopic eye may make it challenging to diagnose MEWDS-associated fundus changes.

KW - Adult

KW - Female

KW - Fluorescein Angiography

KW - Fundus Oculi

KW - Humans

KW - Lacquer

KW - Myopia/complications

KW - Retinal Diseases/diagnosis

KW - Tomography, Optical Coherence

KW - White Dot Syndromes

U2 - 10.1055/a-1515-6065

DO - 10.1055/a-1515-6065

M3 - SCORING: Journal article

C2 - 34327688

VL - 238

SP - 1098

EP - 1100

JO - KLIN MONATSBL AUGENH

JF - KLIN MONATSBL AUGENH

SN - 0023-2165

IS - 10

ER -