Multiple Abszesse nach Südamerikakreuzfahrt
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Multiple Abszesse nach Südamerikakreuzfahrt. / Reynolds, Kristina; Schofer, N; Zengin, E; Lohse, A W; Faiss, S; Schmiedel, S.
In: INTERNIST, Vol. 57, No. 3, 03.2016, p. 284-8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Multiple Abszesse nach Südamerikakreuzfahrt
AU - Reynolds, Kristina
AU - Schofer, N
AU - Zengin, E
AU - Lohse, A W
AU - Faiss, S
AU - Schmiedel, S
PY - 2016/3
Y1 - 2016/3
N2 - We report a case of an extracutaneous involvement of pyoderma gangrenosum. The patient initially presented with multiple sterile abscesses of the skin, heart, prostate, and kidney. Extracutaneous involvement in pyoderma gangrenosum is very rare. Confirmation of the diagnosis was only possible after exclusion of other relevant differential diagnoses. Continuous search for microbes proved negative and after an empiric therapeutic attempt with prednisolone, the patient improved quickly. However, each time we reduced the steroids even in combination with methotrexate or with azathioprine the patient relapsed. Only after therapy with the tumor necrosis factor-α-inhibitor infliximab was permanent remission achieved.
AB - We report a case of an extracutaneous involvement of pyoderma gangrenosum. The patient initially presented with multiple sterile abscesses of the skin, heart, prostate, and kidney. Extracutaneous involvement in pyoderma gangrenosum is very rare. Confirmation of the diagnosis was only possible after exclusion of other relevant differential diagnoses. Continuous search for microbes proved negative and after an empiric therapeutic attempt with prednisolone, the patient improved quickly. However, each time we reduced the steroids even in combination with methotrexate or with azathioprine the patient relapsed. Only after therapy with the tumor necrosis factor-α-inhibitor infliximab was permanent remission achieved.
KW - Abscess
KW - Aged
KW - Dermatologic Agents
KW - Diagnosis, Differential
KW - Humans
KW - Infliximab
KW - Latin America
KW - Male
KW - Pyoderma Gangrenosum
KW - Travel
KW - Treatment Outcome
KW - Case Reports
KW - Journal Article
U2 - 10.1007/s00108-015-0004-8
DO - 10.1007/s00108-015-0004-8
M3 - SCORING: Zeitschriftenaufsatz
C2 - 26782091
VL - 57
SP - 284
EP - 288
JO - INTERNIST
JF - INTERNIST
SN - 0020-9554
IS - 3
ER -