Multi-detector computed tomography to analyze in-stent restenoses at different heart rates.
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Multi-detector computed tomography to analyze in-stent restenoses at different heart rates. / Köster, Ralf; van Stevendaal, U; Grass, M; Yamamura, Jin; Kähler, Jan; Adam, Gerhard; Meinertz, Thomas; Begemann, Philipp.
In: ROFO-FORTSCHR RONTG, Vol. 180, No. 9, 9, 2008, p. 821-831.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Multi-detector computed tomography to analyze in-stent restenoses at different heart rates.
AU - Köster, Ralf
AU - van Stevendaal, U
AU - Grass, M
AU - Yamamura, Jin
AU - Kähler, Jan
AU - Adam, Gerhard
AU - Meinertz, Thomas
AU - Begemann, Philipp
PY - 2008
Y1 - 2008
N2 - PURPOSE: This study was performed to evaluate the visualization of coronary in-stent restenosis by multi-detector computed tomography (MDCT). MATERIALS AND METHODS: A restenosis phantom with different stented stenoses was used. The phantom was placed into a dynamic heart phantom with heart rates from 40 to 120 bpm. MDCT was performed with two scan protocols: a standard and an ultra-high resolution scan protocol. RESULTS: Using the ultra-high resolution protocol, artifacts occurred at 0.6 mm around the stent struts (p <0.001). Artifacts compromised the discrimination between no stenosis and low-grade stenosis. Approximately 73% of the central lumen diameter was able to be assessed without limiting artifacts allowing the discrimination of no or low vs. moderate and high-grade stenoses (p <0.05). Using the standard protocol in the dynamic phantom, the image quality and visibility of stenoses decreased with an increasing heart rate (p <0.0002 and p <0.004). This was able to be compensated by analysis in an appropriate RR-interval. At the optimal RR-interval, an assessment of the grade of stenoses > 30% was feasible up to 120 bpm. CONCLUSION: Multi-detector computed tomography ultra-high resolution scans allowed the assessment of a wide range of degrees of in-stent restenoses. In this experimental setup, standard protocols allowed a discrimination of low, moderate and high-grade stenoses even at heart rates above 100 bpm.
AB - PURPOSE: This study was performed to evaluate the visualization of coronary in-stent restenosis by multi-detector computed tomography (MDCT). MATERIALS AND METHODS: A restenosis phantom with different stented stenoses was used. The phantom was placed into a dynamic heart phantom with heart rates from 40 to 120 bpm. MDCT was performed with two scan protocols: a standard and an ultra-high resolution scan protocol. RESULTS: Using the ultra-high resolution protocol, artifacts occurred at 0.6 mm around the stent struts (p <0.001). Artifacts compromised the discrimination between no stenosis and low-grade stenosis. Approximately 73% of the central lumen diameter was able to be assessed without limiting artifacts allowing the discrimination of no or low vs. moderate and high-grade stenoses (p <0.05). Using the standard protocol in the dynamic phantom, the image quality and visibility of stenoses decreased with an increasing heart rate (p <0.0002 and p <0.004). This was able to be compensated by analysis in an appropriate RR-interval. At the optimal RR-interval, an assessment of the grade of stenoses > 30% was feasible up to 120 bpm. CONCLUSION: Multi-detector computed tomography ultra-high resolution scans allowed the assessment of a wide range of degrees of in-stent restenoses. In this experimental setup, standard protocols allowed a discrimination of low, moderate and high-grade stenoses even at heart rates above 100 bpm.
M3 - SCORING: Zeitschriftenaufsatz
VL - 180
SP - 821
EP - 831
JO - ROFO-FORTSCHR RONTG
JF - ROFO-FORTSCHR RONTG
SN - 1438-9029
IS - 9
M1 - 9
ER -
