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MRI demyelination pattern and clinical course in a child with cerebral X-linked adrenoleukodystrophy (X-ALD)

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MRI demyelination pattern and clinical course in a child with cerebral X-linked adrenoleukodystrophy (X-ALD). / Nowak, Johannes; Löbel, Ulrike; Wölfl, Matthias; Schlegel, Paul-Gerhardt; Warmuth-Metz, Monika.

In: Acta Radiol Open, Vol. 4, No. 4, 04.2015.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Nowak, J, Löbel, U, Wölfl, M, Schlegel, P-G & Warmuth-Metz, M 2015, 'MRI demyelination pattern and clinical course in a child with cerebral X-linked adrenoleukodystrophy (X-ALD)', Acta Radiol Open, vol. 4, no. 4. https://doi.org/10.1177/2047981615573655

APA

Nowak, J., Löbel, U., Wölfl, M., Schlegel, P-G., & Warmuth-Metz, M. (2015). MRI demyelination pattern and clinical course in a child with cerebral X-linked adrenoleukodystrophy (X-ALD). Acta Radiol Open, 4(4). https://doi.org/10.1177/2047981615573655

Vancouver

Nowak J, Löbel U, Wölfl M, Schlegel P-G, Warmuth-Metz M. MRI demyelination pattern and clinical course in a child with cerebral X-linked adrenoleukodystrophy (X-ALD). Acta Radiol Open. 2015 Apr;4(4). https://doi.org/10.1177/2047981615573655

Bibtex

@article{11b5f0efb34a4d2ab92a99fa04b99959,
title = "MRI demyelination pattern and clinical course in a child with cerebral X-linked adrenoleukodystrophy (X-ALD)",
abstract = "The clinical spectrum in boys with X-linked adrenoleukodystrophy (X-ALD) ranges from isolated adrenocortical insufficiency and slowly progressive myelopathy to devastating cerebral demyelination. In the individual case, the disease course still remains unpredictable. Research findings suggest an important role of brain magnetic resonance imaging (MRI) lesion patterns as prognostic markers for X-ALD. Hence, familiarity with imaging features of childhood X-ALD in combination with clinical manifestation is required in order to stratify affected patients for therapy. We report on MRI findings and clinical course of cerebral X-ALD in a young boy with a rare subtype of white matter demyelination.",
author = "Johannes Nowak and Ulrike L{\"o}bel and Matthias W{\"o}lfl and Paul-Gerhardt Schlegel and Monika Warmuth-Metz",
year = "2015",
month = apr,
doi = "10.1177/2047981615573655",
language = "English",
volume = "4",
journal = "Acta Radiol Open",
issn = "2058-4601",
number = "4",

}

RIS

TY - JOUR

T1 - MRI demyelination pattern and clinical course in a child with cerebral X-linked adrenoleukodystrophy (X-ALD)

AU - Nowak, Johannes

AU - Löbel, Ulrike

AU - Wölfl, Matthias

AU - Schlegel, Paul-Gerhardt

AU - Warmuth-Metz, Monika

PY - 2015/4

Y1 - 2015/4

N2 - The clinical spectrum in boys with X-linked adrenoleukodystrophy (X-ALD) ranges from isolated adrenocortical insufficiency and slowly progressive myelopathy to devastating cerebral demyelination. In the individual case, the disease course still remains unpredictable. Research findings suggest an important role of brain magnetic resonance imaging (MRI) lesion patterns as prognostic markers for X-ALD. Hence, familiarity with imaging features of childhood X-ALD in combination with clinical manifestation is required in order to stratify affected patients for therapy. We report on MRI findings and clinical course of cerebral X-ALD in a young boy with a rare subtype of white matter demyelination.

AB - The clinical spectrum in boys with X-linked adrenoleukodystrophy (X-ALD) ranges from isolated adrenocortical insufficiency and slowly progressive myelopathy to devastating cerebral demyelination. In the individual case, the disease course still remains unpredictable. Research findings suggest an important role of brain magnetic resonance imaging (MRI) lesion patterns as prognostic markers for X-ALD. Hence, familiarity with imaging features of childhood X-ALD in combination with clinical manifestation is required in order to stratify affected patients for therapy. We report on MRI findings and clinical course of cerebral X-ALD in a young boy with a rare subtype of white matter demyelination.

U2 - 10.1177/2047981615573655

DO - 10.1177/2047981615573655

M3 - SCORING: Journal article

C2 - 25848550

VL - 4

JO - Acta Radiol Open

JF - Acta Radiol Open

SN - 2058-4601

IS - 4

ER -