Monitoring of loss of heterozygosity in serum microsatellite DNA among patients with gastrointestinal stromal tumors indicates tumor recurrence.
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Abstract
Patients with gastrointestinal stromal tumors (GIST) harbor increased levels of circulating tumor DNA in their peripheral blood. In the current study, the aim was to investigate whether the frequency of loss of heterozygosity (LOH) on cell-free DNA in blood may reflect tumor stage and recurrent disease of these patients.
Bibliographical data
| Original language | English |
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| Article number | 1 |
| ISSN | 0022-4804 |
| Publication status | Published - 2011 |
| pubmed | 20417938 |
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