Molecular targeted therapies for breast cancer treatment.
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Molecular targeted therapies for breast cancer treatment. / Schlotter, Claus M; Vogt, Ulf; Allgayer, Heike; Brandt, Burkhard.
In: BREAST CANCER RES, Vol. 10, No. 4, 4, 2008, p. 211.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Molecular targeted therapies for breast cancer treatment.
AU - Schlotter, Claus M
AU - Vogt, Ulf
AU - Allgayer, Heike
AU - Brandt, Burkhard
PY - 2008
Y1 - 2008
N2 - Targeting the oestrogen receptor, HER2 (human epidermal growth factor receptor 2) and vascular endothelial growth factor has markedly improved breast cancer therapy. New targeted therapeutic approaches to induction of apoptosis or inhibition of anti-apoptosis, cell cycle progression, signal transduction and angiogenesis are described. The molecular pathways and their inhibitory or repair mechanisms are discussed in the preclinical and clinical settings.
AB - Targeting the oestrogen receptor, HER2 (human epidermal growth factor receptor 2) and vascular endothelial growth factor has markedly improved breast cancer therapy. New targeted therapeutic approaches to induction of apoptosis or inhibition of anti-apoptosis, cell cycle progression, signal transduction and angiogenesis are described. The molecular pathways and their inhibitory or repair mechanisms are discussed in the preclinical and clinical settings.
U2 - 10.1186/bcr2112
DO - 10.1186/bcr2112
M3 - SCORING: Zeitschriftenaufsatz
VL - 10
SP - 211
JO - BREAST CANCER RES
JF - BREAST CANCER RES
SN - 1465-5411
IS - 4
M1 - 4
ER -