Molecular mechanisms of metastasis.
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Molecular mechanisms of metastasis. / Hoon, Dave S B; Ferris, Robert; Tanaka, Ryo; Chong, Kelly K; Alix-Panabières, Catherine; Pantel, Klaus.
In: J SURG ONCOL, Vol. 103, No. 6, 6, 2011, p. 508-517.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Molecular mechanisms of metastasis.
AU - Hoon, Dave S B
AU - Ferris, Robert
AU - Tanaka, Ryo
AU - Chong, Kelly K
AU - Alix-Panabières, Catherine
AU - Pantel, Klaus
PY - 2011
Y1 - 2011
N2 - The mechanism of metastasis is a complex set of events that build upon each other to achieve successful growth in organ sites beyond the primary tumor. The cumulative events for metastasis of different cancers have both common and specific cancer specific events. This review discusses several key factors in different cancers that are responsible in metastasis, which includes epigenetic regulation of tumor suppressor genes, functional activity of tumor-related chemokine receptors, and circulating tumor cells.
AB - The mechanism of metastasis is a complex set of events that build upon each other to achieve successful growth in organ sites beyond the primary tumor. The cumulative events for metastasis of different cancers have both common and specific cancer specific events. This review discusses several key factors in different cancers that are responsible in metastasis, which includes epigenetic regulation of tumor suppressor genes, functional activity of tumor-related chemokine receptors, and circulating tumor cells.
KW - Humans
KW - Gene Silencing
KW - DNA Methylation
KW - Immunohistochemistry/methods
KW - Gene Expression Regulation, Neoplastic
KW - Melanoma/physiopathology
KW - MicroRNAs
KW - Mouth Neoplasms/physiopathology
KW - Neoplasm Metastasis/diagnosis/genetics/physiopathology
KW - Neoplastic Cells, Circulating/metabolism
KW - Receptors, Chemokine/metabolism
KW - Skin Neoplasms/physiopathology
KW - Humans
KW - Gene Silencing
KW - DNA Methylation
KW - Immunohistochemistry/methods
KW - Gene Expression Regulation, Neoplastic
KW - Melanoma/physiopathology
KW - MicroRNAs
KW - Mouth Neoplasms/physiopathology
KW - Neoplasm Metastasis/diagnosis/genetics/physiopathology
KW - Neoplastic Cells, Circulating/metabolism
KW - Receptors, Chemokine/metabolism
KW - Skin Neoplasms/physiopathology
M3 - SCORING: Journal article
VL - 103
SP - 508
EP - 517
JO - J SURG ONCOL
JF - J SURG ONCOL
SN - 0022-4790
IS - 6
M1 - 6
ER -