Molecular basis of P2-receptor-mediated calcium signaling in activated pancreatic stellate cells.
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Abstract
There is growing evidence that extracellular nucleotide-induced signaling confers to fibrogenesis in liver and pancreas. Pancreatic stellate cells (PSC) are the most important cell type in pancreatic fibrosis. P2 purine and pyrimidine receptors, again, are pivotal mediators of inflammatory and profibrogenic signals. Our aim was to elucidate the underlying signaling components in activated PSC.
Bibliographical data
| Original language | English |
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| Article number | 5 |
| ISSN | 0885-3177 |
| Publication status | Published - 2011 |
| pubmed | 21654543 |
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