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Mixed results for exposure and response prevention therapy in mixed reality for patients with contamination-related obsessive-compulsive disorder: A randomized controlled pilot study

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Mixed results for exposure and response prevention therapy in mixed reality for patients with contamination-related obsessive-compulsive disorder: A randomized controlled pilot study. / Miegel, Franziska; Jelinek, Lena; Moritz, Steffen; Lohse, Luzie; Yassari, Amir H; Bücker, Lara.

In: J CLIN PSYCHOL, Vol. 79, No. 10, 10.2023, p. 2317-2336.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Miegel, F, Jelinek, L, Moritz, S, Lohse, L, Yassari, AH & Bücker, L 2023, 'Mixed results for exposure and response prevention therapy in mixed reality for patients with contamination-related obsessive-compulsive disorder: A randomized controlled pilot study', J CLIN PSYCHOL, vol. 79, no. 10, pp. 2317-2336. https://doi.org/10.1002/jclp.23550

APA

Miegel, F., Jelinek, L., Moritz, S., Lohse, L., Yassari, A. H., & Bücker, L. (2023). Mixed results for exposure and response prevention therapy in mixed reality for patients with contamination-related obsessive-compulsive disorder: A randomized controlled pilot study. J CLIN PSYCHOL, 79(10), 2317-2336. https://doi.org/10.1002/jclp.23550

Vancouver

Miegel F, Jelinek L, Moritz S, Lohse L, Yassari AH, Bücker L. Mixed results for exposure and response prevention therapy in mixed reality for patients with contamination-related obsessive-compulsive disorder: A randomized controlled pilot study. J CLIN PSYCHOL. 2023 Oct;79(10):2317-2336. https://doi.org/10.1002/jclp.23550

Bibtex

@article{e0e4552b157f4d2bb80dbd4d108b7887,
title = "Mixed results for exposure and response prevention therapy in mixed reality for patients with contamination-related obsessive-compulsive disorder: A randomized controlled pilot study",
abstract = "INTRODUCTION: Technology-supported exposure and response prevention (ERP) for patients with obsessive-compulsive disorder (OCD) as tested in clinical research, holds promise but also has limitations. The present study aims to overcome these limitations by using mixed reality for ERP (MERP). The objectives of this pilot study were to evaluate the safety, feasibility, and acceptance of MERP and to identify possible obstacles.METHODS: Twenty inpatients with contamination-related OCD were recruited and randomized to two conditions: MERP (six sessions in 3 weeks) and care as usual treatment. Patients were assessed before treatment (baseline), after the 3-week intervention period (post), as well as 3 months after post assessment (follow-up) regarding symptomatology (Y-BOCS).RESULTS: Results showed a similar reduction in symptomatology in both groups from baseline to post. Regarding safety, no clinically significant deterioration was detected in the MERP group. Patients' evaluation of the MERP was heterogeneous. The qualitative feedback provided helpful indications for further development of the software. Sense of presence was below the midpoint of the scales.CONCLUSION: This is the first study evaluating a MERP for patients with OCD that shows cautious evidence for the acceptance and safety of MERP. The results of the subjective evaluation suggest revisions of the software.",
keywords = "Humans, Pilot Projects, Treatment Outcome, Cognitive Behavioral Therapy/methods, Augmented Reality, Obsessive-Compulsive Disorder/therapy",
author = "Franziska Miegel and Lena Jelinek and Steffen Moritz and Luzie Lohse and Yassari, {Amir H} and Lara B{\"u}cker",
note = "{\textcopyright} 2023 Wiley Periodicals LLC.",
year = "2023",
month = oct,
doi = "10.1002/jclp.23550",
language = "English",
volume = "79",
pages = "2317--2336",
journal = "J CLIN PSYCHOL",
issn = "0021-9762",
publisher = "John Wiley and Sons Inc.",
number = "10",

}

RIS

TY - JOUR

T1 - Mixed results for exposure and response prevention therapy in mixed reality for patients with contamination-related obsessive-compulsive disorder: A randomized controlled pilot study

AU - Miegel, Franziska

AU - Jelinek, Lena

AU - Moritz, Steffen

AU - Lohse, Luzie

AU - Yassari, Amir H

AU - Bücker, Lara

N1 - © 2023 Wiley Periodicals LLC.

PY - 2023/10

Y1 - 2023/10

N2 - INTRODUCTION: Technology-supported exposure and response prevention (ERP) for patients with obsessive-compulsive disorder (OCD) as tested in clinical research, holds promise but also has limitations. The present study aims to overcome these limitations by using mixed reality for ERP (MERP). The objectives of this pilot study were to evaluate the safety, feasibility, and acceptance of MERP and to identify possible obstacles.METHODS: Twenty inpatients with contamination-related OCD were recruited and randomized to two conditions: MERP (six sessions in 3 weeks) and care as usual treatment. Patients were assessed before treatment (baseline), after the 3-week intervention period (post), as well as 3 months after post assessment (follow-up) regarding symptomatology (Y-BOCS).RESULTS: Results showed a similar reduction in symptomatology in both groups from baseline to post. Regarding safety, no clinically significant deterioration was detected in the MERP group. Patients' evaluation of the MERP was heterogeneous. The qualitative feedback provided helpful indications for further development of the software. Sense of presence was below the midpoint of the scales.CONCLUSION: This is the first study evaluating a MERP for patients with OCD that shows cautious evidence for the acceptance and safety of MERP. The results of the subjective evaluation suggest revisions of the software.

AB - INTRODUCTION: Technology-supported exposure and response prevention (ERP) for patients with obsessive-compulsive disorder (OCD) as tested in clinical research, holds promise but also has limitations. The present study aims to overcome these limitations by using mixed reality for ERP (MERP). The objectives of this pilot study were to evaluate the safety, feasibility, and acceptance of MERP and to identify possible obstacles.METHODS: Twenty inpatients with contamination-related OCD were recruited and randomized to two conditions: MERP (six sessions in 3 weeks) and care as usual treatment. Patients were assessed before treatment (baseline), after the 3-week intervention period (post), as well as 3 months after post assessment (follow-up) regarding symptomatology (Y-BOCS).RESULTS: Results showed a similar reduction in symptomatology in both groups from baseline to post. Regarding safety, no clinically significant deterioration was detected in the MERP group. Patients' evaluation of the MERP was heterogeneous. The qualitative feedback provided helpful indications for further development of the software. Sense of presence was below the midpoint of the scales.CONCLUSION: This is the first study evaluating a MERP for patients with OCD that shows cautious evidence for the acceptance and safety of MERP. The results of the subjective evaluation suggest revisions of the software.

KW - Humans

KW - Pilot Projects

KW - Treatment Outcome

KW - Cognitive Behavioral Therapy/methods

KW - Augmented Reality

KW - Obsessive-Compulsive Disorder/therapy

U2 - 10.1002/jclp.23550

DO - 10.1002/jclp.23550

M3 - SCORING: Journal article

C2 - 37317567

VL - 79

SP - 2317

EP - 2336

JO - J CLIN PSYCHOL

JF - J CLIN PSYCHOL

SN - 0021-9762

IS - 10

ER -