Minimum inhibitory concentrations and sequencing data have to be analysed in more detail to set provisional epidemiological cut-off values for Mycobacterium tuberculosis complex

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Minimum inhibitory concentrations and sequencing data have to be analysed in more detail to set provisional epidemiological cut-off values for Mycobacterium tuberculosis complex. / Köser, Claudio U; Maurer, Florian P.

In: EUR RESPIR J, Vol. 61, No. 5, 2202397, 05.2023.

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@article{dd60640cbbe3493d868f22ccb8c3d741,
title = "Minimum inhibitory concentrations and sequencing data have to be analysed in more detail to set provisional epidemiological cut-off values for Mycobacterium tuberculosis complex",
abstract = "There is a clear need for a high-quality broth microdilution (BMD) assay for quantitative antimicrobial susceptibility testing (AST) for the Mycobacterium tuberculosis complex (MTBC) [1]. The BMD plate developed by the CRyPTIC Consortium, therefore, represents an important advance [2]. However, the analysis of the resulting data has several limitations.",
keywords = "Humans, Mycobacterium tuberculosis/genetics, Antitubercular Agents/pharmacology, Tuberculosis/epidemiology, Microbial Sensitivity Tests",
author = "K{\"o}ser, {Claudio U} and Maurer, {Florian P}",
year = "2023",
month = may,
doi = "10.1183/13993003.02397-2022",
language = "English",
volume = "61",
journal = "EUR RESPIR J",
issn = "0903-1936",
publisher = "European Respiratory Society",
number = "5",

}

RIS

TY - JOUR

T1 - Minimum inhibitory concentrations and sequencing data have to be analysed in more detail to set provisional epidemiological cut-off values for Mycobacterium tuberculosis complex

AU - Köser, Claudio U

AU - Maurer, Florian P

PY - 2023/5

Y1 - 2023/5

N2 - There is a clear need for a high-quality broth microdilution (BMD) assay for quantitative antimicrobial susceptibility testing (AST) for the Mycobacterium tuberculosis complex (MTBC) [1]. The BMD plate developed by the CRyPTIC Consortium, therefore, represents an important advance [2]. However, the analysis of the resulting data has several limitations.

AB - There is a clear need for a high-quality broth microdilution (BMD) assay for quantitative antimicrobial susceptibility testing (AST) for the Mycobacterium tuberculosis complex (MTBC) [1]. The BMD plate developed by the CRyPTIC Consortium, therefore, represents an important advance [2]. However, the analysis of the resulting data has several limitations.

KW - Humans

KW - Mycobacterium tuberculosis/genetics

KW - Antitubercular Agents/pharmacology

KW - Tuberculosis/epidemiology

KW - Microbial Sensitivity Tests

U2 - 10.1183/13993003.02397-2022

DO - 10.1183/13993003.02397-2022

M3 - Letter

C2 - 37147011

VL - 61

JO - EUR RESPIR J

JF - EUR RESPIR J

SN - 0903-1936

IS - 5

M1 - 2202397

ER -