Microstructural properties of the mid-facial bones in relation to the distribution of occlusal loading

Aleksa Janovic; Petar Milovanovic; Igor Saveljic; Dalibor Nikolic; Michael Hahn; Zoran Rakocevic; Nenad Filipovic; Michael Amling; Bjoern Busse; Marija Djuric

doi:10.1016/j.bone.2014.07.032

Microstructural properties of the mid-facial bones in relation to the distribution of occlusal loading

Standard

Microstructural properties of the mid-facial bones in relation to the distribution of occlusal loading. / Janovic, Aleksa; Milovanovic, Petar; Saveljic, Igor; Nikolic, Dalibor; Hahn, Michael; Rakocevic, Zoran; Filipovic, Nenad; Amling, Michael ; Busse, Bjoern; Djuric, Marija.

In: BONE, Vol. 68, 11.2014, p. 108-14.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Janovic, A, Milovanovic, P, Saveljic, I, Nikolic, D, Hahn, M, Rakocevic, Z, Filipovic, N, Amling, M , Busse, B & Djuric, M 2014, 'Microstructural properties of the mid-facial bones in relation to the distribution of occlusal loading', BONE, vol. 68, pp. 108-14. https://doi.org/10.1016/j.bone.2014.07.032

APA

Janovic, A., Milovanovic, P., Saveljic, I., Nikolic, D., Hahn, M., Rakocevic, Z., Filipovic, N., Amling, M., Busse, B., & Djuric, M. (2014). Microstructural properties of the mid-facial bones in relation to the distribution of occlusal loading. BONE, 68, 108-14. https://doi.org/10.1016/j.bone.2014.07.032

Vancouver

Janovic A, Milovanovic P, Saveljic I, Nikolic D, Hahn M, Rakocevic Z et al. Microstructural properties of the mid-facial bones in relation to the distribution of occlusal loading. BONE. 2014 Nov;68:108-14. https://doi.org/10.1016/j.bone.2014.07.032

Bibtex

@article{cf3c7f32dce2442d87a8481ed1a10633,

title = "Microstructural properties of the mid-facial bones in relation to the distribution of occlusal loading",

abstract = "Although the concept of the occlusal load transfer through the facial skeleton along the buttresses has been extensively studied, there has been no study to link microarchitecture of the mid-facial bones to the occlusal load distribution. The aim of this study was to analyze micro-structural properties of the mid-facial bones in relation to occlusal stress. The study was performed by combining the three-dimensional finite element analysis (3D FEA) and micro-computed tomography analysis (micro-CT). Clenching was simulated on the computer model of the adult male human skull which was also used as a source of bone specimens. After the FEA was run, stress was measured at the specific sites in cortical shell and trabecular bone of the model along and between the buttresses. From the corresponding sites on the skull, twenty-five cortical and thirteen cancellous bone specimens were harvested. The specimens were classified into high stress or low stress group based on the stress levels measured via the FEA. Micro-architecture of each specimen was assessed by micro-CT. In the high stress group, cortical bone showed a tendency toward greater thickness and density, lower porosity, and greater pore separation. Stress-related differences in microstructure between the groups were more pronounced in trabecular bone, which showed significantly greater bone volume fraction (BV/TV) and trabecular thickness (Tb.Th) in the high stress group. Our results suggest that the mid-facial bones in the adult dentate male skull exhibit regional variations in cortical and trabecular bone micro-architecture that could be a consequence of different occlusal stress.",

keywords = "Bone Density, Facial Bones, Humans, Male, Stress, Mechanical, Weight-Bearing",

author = "Aleksa Janovic and Petar Milovanovic and Igor Saveljic and Dalibor Nikolic and Michael Hahn and Zoran Rakocevic and Nenad Filipovic and Michael Amling and Bjoern Busse and Marija Djuric",

year = "2014",

month = nov,

doi = "10.1016/j.bone.2014.07.032",

language = "English",

volume = "68",

pages = "108--14",

journal = "BONE",

issn = "8756-3282",

publisher = "Elsevier Inc.",

}

RIS

TY - JOUR

T1 - Microstructural properties of the mid-facial bones in relation to the distribution of occlusal loading

AU - Janovic, Aleksa

AU - Milovanovic, Petar

AU - Saveljic, Igor

AU - Nikolic, Dalibor

AU - Hahn, Michael

AU - Rakocevic, Zoran

AU - Filipovic, Nenad

AU - Amling, Michael

AU - Busse, Bjoern

AU - Djuric, Marija

PY - 2014/11

Y1 - 2014/11

N2 - Although the concept of the occlusal load transfer through the facial skeleton along the buttresses has been extensively studied, there has been no study to link microarchitecture of the mid-facial bones to the occlusal load distribution. The aim of this study was to analyze micro-structural properties of the mid-facial bones in relation to occlusal stress. The study was performed by combining the three-dimensional finite element analysis (3D FEA) and micro-computed tomography analysis (micro-CT). Clenching was simulated on the computer model of the adult male human skull which was also used as a source of bone specimens. After the FEA was run, stress was measured at the specific sites in cortical shell and trabecular bone of the model along and between the buttresses. From the corresponding sites on the skull, twenty-five cortical and thirteen cancellous bone specimens were harvested. The specimens were classified into high stress or low stress group based on the stress levels measured via the FEA. Micro-architecture of each specimen was assessed by micro-CT. In the high stress group, cortical bone showed a tendency toward greater thickness and density, lower porosity, and greater pore separation. Stress-related differences in microstructure between the groups were more pronounced in trabecular bone, which showed significantly greater bone volume fraction (BV/TV) and trabecular thickness (Tb.Th) in the high stress group. Our results suggest that the mid-facial bones in the adult dentate male skull exhibit regional variations in cortical and trabecular bone micro-architecture that could be a consequence of different occlusal stress.

AB - Although the concept of the occlusal load transfer through the facial skeleton along the buttresses has been extensively studied, there has been no study to link microarchitecture of the mid-facial bones to the occlusal load distribution. The aim of this study was to analyze micro-structural properties of the mid-facial bones in relation to occlusal stress. The study was performed by combining the three-dimensional finite element analysis (3D FEA) and micro-computed tomography analysis (micro-CT). Clenching was simulated on the computer model of the adult male human skull which was also used as a source of bone specimens. After the FEA was run, stress was measured at the specific sites in cortical shell and trabecular bone of the model along and between the buttresses. From the corresponding sites on the skull, twenty-five cortical and thirteen cancellous bone specimens were harvested. The specimens were classified into high stress or low stress group based on the stress levels measured via the FEA. Micro-architecture of each specimen was assessed by micro-CT. In the high stress group, cortical bone showed a tendency toward greater thickness and density, lower porosity, and greater pore separation. Stress-related differences in microstructure between the groups were more pronounced in trabecular bone, which showed significantly greater bone volume fraction (BV/TV) and trabecular thickness (Tb.Th) in the high stress group. Our results suggest that the mid-facial bones in the adult dentate male skull exhibit regional variations in cortical and trabecular bone micro-architecture that could be a consequence of different occlusal stress.

KW - Bone Density

KW - Facial Bones

KW - Humans

KW - Male

KW - Stress, Mechanical

KW - Weight-Bearing

U2 - 10.1016/j.bone.2014.07.032

DO - 10.1016/j.bone.2014.07.032

M3 - SCORING: Journal article

C2 - 25093265

VL - 68

SP - 108

EP - 114

JO - BONE

JF - BONE

SN - 8756-3282

ER -