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MicroRNAs in Bone Metastasis

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MicroRNAs in Bone Metastasis. / Hesse, Eric; Taipaleenmäki, Hanna.

In: CURR OSTEOPOROS REP, Vol. 17, No. 3, 06.2019, p. 122-128.

Research output: SCORING: Contribution to journal › SCORING: Review article › Research

Harvard

Hesse, E & Taipaleenmäki, H 2019, 'MicroRNAs in Bone Metastasis', CURR OSTEOPOROS REP, vol. 17, no. 3, pp. 122-128. https://doi.org/10.1007/s11914-019-00510-4

APA

Hesse, E., & Taipaleenmäki, H. (2019). MicroRNAs in Bone Metastasis. CURR OSTEOPOROS REP, 17(3), 122-128. https://doi.org/10.1007/s11914-019-00510-4

Vancouver

Hesse E, Taipaleenmäki H. MicroRNAs in Bone Metastasis. CURR OSTEOPOROS REP. 2019 Jun;17(3):122-128. https://doi.org/10.1007/s11914-019-00510-4

Bibtex

@article{62e3ba6c5eb949ecb3cfae98e0946d53,
title = "MicroRNAs in Bone Metastasis",
abstract = "PURPOSE OF REVIEW: This review provides an update on the recent literature describing the role of microRNAs (miRNAs) in cancer formation and bone metastasis. We confined our focus on osteosarcoma, breast cancer, prostate cancer, and epithelial-mesenchymal transition.RECENT FINDINGS: In all areas covered, major discoveries on the role of miRNAs in tumorigenesis and metastasis have been made. Novel signaling networks were identified with miRNAs having a central function. Potential improvements in the diagnosis of malignant diseases and the long-term follow-up might become possible by the use of miRNAs. Furthermore, miRNAs also have disease-modifying properties and might emerge as a new class of therapeutic molecules. MiRNAs are novel and important regulators of multiple cellular and molecular events. Due to their functions, miRNAs might become useful to improve the diagnosis, follow-up and treatment of cancer, and metastases. Thus, miRNAs are molecules of great interest in translational medicine.",
keywords = "Bone Neoplasms/secondary, Breast Neoplasms/pathology, Epithelial-Mesenchymal Transition, Female, Humans, Male, MicroRNAs/physiology, Osteosarcoma/secondary, Prostatic Neoplasms/pathology",
author = "Eric Hesse and Hanna Taipaleenm{\"a}ki",
year = "2019",
month = jun,
doi = "10.1007/s11914-019-00510-4",
language = "English",
volume = "17",
pages = "122--128",
journal = "CURR OSTEOPOROS REP",
issn = "1544-1873",
publisher = "SPRINGER US",
number = "3",

}

RIS

TY - JOUR

T1 - MicroRNAs in Bone Metastasis

AU - Hesse, Eric

AU - Taipaleenmäki, Hanna

PY - 2019/6

Y1 - 2019/6

N2 - PURPOSE OF REVIEW: This review provides an update on the recent literature describing the role of microRNAs (miRNAs) in cancer formation and bone metastasis. We confined our focus on osteosarcoma, breast cancer, prostate cancer, and epithelial-mesenchymal transition.RECENT FINDINGS: In all areas covered, major discoveries on the role of miRNAs in tumorigenesis and metastasis have been made. Novel signaling networks were identified with miRNAs having a central function. Potential improvements in the diagnosis of malignant diseases and the long-term follow-up might become possible by the use of miRNAs. Furthermore, miRNAs also have disease-modifying properties and might emerge as a new class of therapeutic molecules. MiRNAs are novel and important regulators of multiple cellular and molecular events. Due to their functions, miRNAs might become useful to improve the diagnosis, follow-up and treatment of cancer, and metastases. Thus, miRNAs are molecules of great interest in translational medicine.

AB - PURPOSE OF REVIEW: This review provides an update on the recent literature describing the role of microRNAs (miRNAs) in cancer formation and bone metastasis. We confined our focus on osteosarcoma, breast cancer, prostate cancer, and epithelial-mesenchymal transition.RECENT FINDINGS: In all areas covered, major discoveries on the role of miRNAs in tumorigenesis and metastasis have been made. Novel signaling networks were identified with miRNAs having a central function. Potential improvements in the diagnosis of malignant diseases and the long-term follow-up might become possible by the use of miRNAs. Furthermore, miRNAs also have disease-modifying properties and might emerge as a new class of therapeutic molecules. MiRNAs are novel and important regulators of multiple cellular and molecular events. Due to their functions, miRNAs might become useful to improve the diagnosis, follow-up and treatment of cancer, and metastases. Thus, miRNAs are molecules of great interest in translational medicine.

KW - Bone Neoplasms/secondary

KW - Breast Neoplasms/pathology

KW - Epithelial-Mesenchymal Transition

KW - Female

KW - Humans

KW - Male

KW - MicroRNAs/physiology

KW - Osteosarcoma/secondary

KW - Prostatic Neoplasms/pathology

U2 - 10.1007/s11914-019-00510-4

DO - 10.1007/s11914-019-00510-4

M3 - SCORING: Review article

C2 - 30905007

VL - 17

SP - 122

EP - 128

JO - CURR OSTEOPOROS REP

JF - CURR OSTEOPOROS REP

SN - 1544-1873

IS - 3

ER -