MicroRNA Profiling of Alzheimer's Disease Cerebrospinal Fluid
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MicroRNA Profiling of Alzheimer's Disease Cerebrospinal Fluid. / Denk, Johannes; Jahn, Holger.
Biomarkers for Alzheimer’s Disease Drug Development. ed. / Robert G. Perneczky. Vol. 1750 1. ed. Humana Press, 2018. p. 93-107 (Methods in Molecular Biology; Vol. 1750).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
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TY - CHAP
T1 - MicroRNA Profiling of Alzheimer's Disease Cerebrospinal Fluid
AU - Denk, Johannes
AU - Jahn, Holger
PY - 2018
Y1 - 2018
N2 - MicroRNAs (miRNAs) are a class of small, highly conserved, and noncoding RNAs that modulate gene expression by regulating the activity and stability of target mRNAs. MiRNAs play significant roles by controlling fundamental cellular processes and its deregulation is associated with various diseases. Ubiquitous expression and its release into circulation make them interesting biomarkers, which can be measured by different platforms. In this book chapter, we provide a specific protocol that describes the detection of circulating miRNAs in CSF by using RT-qPCR.
AB - MicroRNAs (miRNAs) are a class of small, highly conserved, and noncoding RNAs that modulate gene expression by regulating the activity and stability of target mRNAs. MiRNAs play significant roles by controlling fundamental cellular processes and its deregulation is associated with various diseases. Ubiquitous expression and its release into circulation make them interesting biomarkers, which can be measured by different platforms. In this book chapter, we provide a specific protocol that describes the detection of circulating miRNAs in CSF by using RT-qPCR.
KW - Journal Article
U2 - 10.1007/978-1-4939-7704-8_6
DO - 10.1007/978-1-4939-7704-8_6
M3 - SCORING: Contribution to collected editions/anthologies
C2 - 29512067
SN - 978-1-4939-7703-1 Softcover ISBN
VL - 1750
T3 - Methods in Molecular Biology
SP - 93
EP - 107
BT - Biomarkers for Alzheimer’s Disease Drug Development
A2 - Perneczky, Robert G.
PB - Humana Press
ER -