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Metronomic trofosfamide inhibits progression of human lung cancer xenografts by exerting anti-angiogenic effects.

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Metronomic trofosfamide inhibits progression of human lung cancer xenografts by exerting anti-angiogenic effects. / Klink, Thorsten; Bela, C; Stoelting, S; Peters, S O; Broll, R; Wagner, T.

In: J CANCER RES CLIN, Vol. 132, No. 10, 10, 2006, p. 643-652.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Klink, T, Bela, C, Stoelting, S, Peters, SO, Broll, R & Wagner, T 2006, 'Metronomic trofosfamide inhibits progression of human lung cancer xenografts by exerting anti-angiogenic effects.', J CANCER RES CLIN, vol. 132, no. 10, 10, pp. 643-652. <http://www.ncbi.nlm.nih.gov/pubmed/16761121?dopt=Citation>

APA

Klink, T., Bela, C., Stoelting, S., Peters, S. O., Broll, R., & Wagner, T. (2006). Metronomic trofosfamide inhibits progression of human lung cancer xenografts by exerting anti-angiogenic effects. J CANCER RES CLIN, 132(10), 643-652. [10]. http://www.ncbi.nlm.nih.gov/pubmed/16761121?dopt=Citation

Vancouver

Klink T, Bela C, Stoelting S, Peters SO, Broll R, Wagner T. Metronomic trofosfamide inhibits progression of human lung cancer xenografts by exerting anti-angiogenic effects. J CANCER RES CLIN. 2006;132(10):643-652. 10.

Bibtex

@article{f924f7666e154f609fd6c7ae57b01cef,
title = "Metronomic trofosfamide inhibits progression of human lung cancer xenografts by exerting anti-angiogenic effects.",
abstract = "Recent studies of conventional chemotherapeutic drugs administered in metronomic therapy schedules showed remarkable inhibitory effects on tumor angiogenesis. Subsequent and prolonged tumor regression was achieved moreover by circumventing acquired drug resistance. In this study, metronomic and conventional trofosfamide were compared on human NSCLC xenograft {"}LX-1.{"}",
keywords = "Animals, Humans, Female, Time Factors, Mice, Tumor Cells, Cultured, Drug Administration Schedule, Apoptosis/drug effects, Mice, Nude, Xenograft Model Antitumor Assays, Inhibitory Concentration 50, Angiogenesis Inhibitors/*administration & dosage/therapeutic use/toxicity, Antineoplastic Agents, Alkylating/*administration & dosage/therapeutic use/toxicity, Carcinoma, Non-Small-Cell Lung/*drug therapy/pathology, Cyclophosphamide/administration & dosage/*analogs & derivatives/therapeutic use/toxicity, Endothelial Cells/drug effects/metabolism, Lung Neoplasms/*drug therapy, Animals, Humans, Female, Time Factors, Mice, Tumor Cells, Cultured, Drug Administration Schedule, Apoptosis/drug effects, Mice, Nude, Xenograft Model Antitumor Assays, Inhibitory Concentration 50, Angiogenesis Inhibitors/*administration & dosage/therapeutic use/toxicity, Antineoplastic Agents, Alkylating/*administration & dosage/therapeutic use/toxicity, Carcinoma, Non-Small-Cell Lung/*drug therapy/pathology, Cyclophosphamide/administration & dosage/*analogs & derivatives/therapeutic use/toxicity, Endothelial Cells/drug effects/metabolism, Lung Neoplasms/*drug therapy",
author = "Thorsten Klink and C Bela and S Stoelting and Peters, {S O} and R Broll and T Wagner",
year = "2006",
language = "English",
volume = "132",
pages = "643--652",
journal = "J CANCER RES CLIN",
issn = "0171-5216",
publisher = "Springer",
number = "10",

}

RIS

TY - JOUR

T1 - Metronomic trofosfamide inhibits progression of human lung cancer xenografts by exerting anti-angiogenic effects.

AU - Klink, Thorsten

AU - Bela, C

AU - Stoelting, S

AU - Peters, S O

AU - Broll, R

AU - Wagner, T

PY - 2006

Y1 - 2006

N2 - Recent studies of conventional chemotherapeutic drugs administered in metronomic therapy schedules showed remarkable inhibitory effects on tumor angiogenesis. Subsequent and prolonged tumor regression was achieved moreover by circumventing acquired drug resistance. In this study, metronomic and conventional trofosfamide were compared on human NSCLC xenograft "LX-1."

AB - Recent studies of conventional chemotherapeutic drugs administered in metronomic therapy schedules showed remarkable inhibitory effects on tumor angiogenesis. Subsequent and prolonged tumor regression was achieved moreover by circumventing acquired drug resistance. In this study, metronomic and conventional trofosfamide were compared on human NSCLC xenograft "LX-1."

KW - Animals

KW - Humans

KW - Female

KW - Time Factors

KW - Mice

KW - Tumor Cells, Cultured

KW - Drug Administration Schedule

KW - Apoptosis/drug effects

KW - Mice, Nude

KW - Xenograft Model Antitumor Assays

KW - Inhibitory Concentration 50

KW - Angiogenesis Inhibitors/administration & dosage/therapeutic use/toxicity

KW - Antineoplastic Agents, Alkylating/administration & dosage/therapeutic use/toxicity

KW - Carcinoma, Non-Small-Cell Lung/drug therapy/pathology

KW - Cyclophosphamide/administration & dosage/analogs & derivatives/therapeutic use/toxicity

KW - Endothelial Cells/drug effects/metabolism

KW - Lung Neoplasms/drug therapy

KW - Animals

KW - Humans

KW - Female

KW - Time Factors

KW - Mice

KW - Tumor Cells, Cultured

KW - Drug Administration Schedule

KW - Apoptosis/drug effects

KW - Mice, Nude

KW - Xenograft Model Antitumor Assays

KW - Inhibitory Concentration 50

KW - Angiogenesis Inhibitors/administration & dosage/therapeutic use/toxicity

KW - Antineoplastic Agents, Alkylating/administration & dosage/therapeutic use/toxicity

KW - Carcinoma, Non-Small-Cell Lung/drug therapy/pathology

KW - Cyclophosphamide/administration & dosage/analogs & derivatives/therapeutic use/toxicity

KW - Endothelial Cells/drug effects/metabolism

KW - Lung Neoplasms/drug therapy

M3 - SCORING: Journal article

VL - 132

SP - 643

EP - 652

JO - J CANCER RES CLIN

JF - J CANCER RES CLIN

SN - 0171-5216

IS - 10

M1 - 10

ER -