Metabolic Turnover Studies to Quantify Energy Uptake by Thermogenic Adipose Tissues of Mice
Related Research units
Abstract
The uptake of glucose, non-esterified fatty acids, and triglycerides into brown adipose tissue is an important determinant of systemic energy metabolism, which can be studied by metabolic turnover studies using radioactive tracers in vivo. Here, we address the uptake of glucose and lipid tracers into metabolically active organs with a focus on thermogenically activated adipose tissues. Uptake by beige and brown adipocytes is highly dependent on conditions such as ambient temperature, but also varies between fasted compared to postprandial states. Accordingly, we provide methodological insights how to quantify glucose and lipid disposal under multiple physiological and environmental conditions.
Bibliographical data
Original language | English |
---|---|
Title of host publication | Brown Adipose Tissue : Methods and Protocols |
REQUIRED books only: Number of pages | 12 |
Place of Publication | New York, NY |
Publisher | HUMANA PRESS INC |
Publication date | 2022 |
Edition | 1 |
Pages | 107-118 |
ISBN (Print) | 978-1-0716-2086-1, 978-1-0716-2089-2 |
ISBN (Electronic) | 978-1-0716-2087-8 |
DOIs | |
Publication status | Published - 2022 |
Comment Deanary
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.
PubMed | 35167093 |
---|