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Mesenchymal stromal cells

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Mesenchymal stromal cells : a novel treatment option for steroid-induced avascular osteonecrosis. / Tzaribachev, Nikolay; Vaegler, Martin; Schaefer, Juergen; Reize, Patrik; Rudert, Maximillian; Handgretinger, Rupert; Müller, Ingo.

In: CAN MED ASSOC J, Vol. 10, No. 3, 03.2008, p. 232-4.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Tzaribachev, N, Vaegler, M, Schaefer, J, Reize, P, Rudert, M, Handgretinger, R & Müller, I 2008, 'Mesenchymal stromal cells: a novel treatment option for steroid-induced avascular osteonecrosis', CAN MED ASSOC J, vol. 10, no. 3, pp. 232-4.

APA

Tzaribachev, N., Vaegler, M., Schaefer, J., Reize, P., Rudert, M., Handgretinger, R., & Müller, I. (2008). Mesenchymal stromal cells: a novel treatment option for steroid-induced avascular osteonecrosis. CAN MED ASSOC J, 10(3), 232-4.

Vancouver

Tzaribachev N, Vaegler M, Schaefer J, Reize P, Rudert M, Handgretinger R et al. Mesenchymal stromal cells: a novel treatment option for steroid-induced avascular osteonecrosis. CAN MED ASSOC J. 2008 Mar;10(3):232-4.

Bibtex

@article{9ce1099d2f0e47bc98c64c4e008ce694,
title = "Mesenchymal stromal cells: a novel treatment option for steroid-induced avascular osteonecrosis",
abstract = "Mesenchymal stromal cells are multipotent cells capable of tissue repair and immune modulation. They are primarily found in bone marrow, but are also present in other tissues of mesenchymal origin, such as fatty tissue, muscle, tendons, etc. MSC can easily be obtained by bone marrow aspiration, showing a rapid expansion in vitro. New protocols enable cell culture without the use of animal-derived sera and artificial growth factors. Avascular necroses of the bone may have different causes. AVN in autoimmune and hematological diseases show a strong association with corticosteroid treatment, which is often unavoidable in severe cases. Until recently, core decompression of the affected osseous area was the standard approach. Because of their differentiation properties, easy accessibility and proliferative capacity, autologous MSCs could potentially complement AVN treatment by adding fresh {"}osteogenic cells{"} to the healing process.",
keywords = "Adrenal Cortex Hormones, Humans, Mesenchymal Stem Cell Transplantation, Osteonecrosis, Stromal Cells",
author = "Nikolay Tzaribachev and Martin Vaegler and Juergen Schaefer and Patrik Reize and Maximillian Rudert and Rupert Handgretinger and Ingo M{\"u}ller",
year = "2008",
month = mar,
language = "English",
volume = "10",
pages = "232--4",
journal = "CAN MED ASSOC J",
issn = "0820-3946",
publisher = "Canadian Medical Association",
number = "3",

}

RIS

TY - JOUR

T1 - Mesenchymal stromal cells

T2 - a novel treatment option for steroid-induced avascular osteonecrosis

AU - Tzaribachev, Nikolay

AU - Vaegler, Martin

AU - Schaefer, Juergen

AU - Reize, Patrik

AU - Rudert, Maximillian

AU - Handgretinger, Rupert

AU - Müller, Ingo

PY - 2008/3

Y1 - 2008/3

N2 - Mesenchymal stromal cells are multipotent cells capable of tissue repair and immune modulation. They are primarily found in bone marrow, but are also present in other tissues of mesenchymal origin, such as fatty tissue, muscle, tendons, etc. MSC can easily be obtained by bone marrow aspiration, showing a rapid expansion in vitro. New protocols enable cell culture without the use of animal-derived sera and artificial growth factors. Avascular necroses of the bone may have different causes. AVN in autoimmune and hematological diseases show a strong association with corticosteroid treatment, which is often unavoidable in severe cases. Until recently, core decompression of the affected osseous area was the standard approach. Because of their differentiation properties, easy accessibility and proliferative capacity, autologous MSCs could potentially complement AVN treatment by adding fresh "osteogenic cells" to the healing process.

AB - Mesenchymal stromal cells are multipotent cells capable of tissue repair and immune modulation. They are primarily found in bone marrow, but are also present in other tissues of mesenchymal origin, such as fatty tissue, muscle, tendons, etc. MSC can easily be obtained by bone marrow aspiration, showing a rapid expansion in vitro. New protocols enable cell culture without the use of animal-derived sera and artificial growth factors. Avascular necroses of the bone may have different causes. AVN in autoimmune and hematological diseases show a strong association with corticosteroid treatment, which is often unavoidable in severe cases. Until recently, core decompression of the affected osseous area was the standard approach. Because of their differentiation properties, easy accessibility and proliferative capacity, autologous MSCs could potentially complement AVN treatment by adding fresh "osteogenic cells" to the healing process.

KW - Adrenal Cortex Hormones

KW - Humans

KW - Mesenchymal Stem Cell Transplantation

KW - Osteonecrosis

KW - Stromal Cells

M3 - SCORING: Journal article

C2 - 18494240

VL - 10

SP - 232

EP - 234

JO - CAN MED ASSOC J

JF - CAN MED ASSOC J

SN - 0820-3946

IS - 3

ER -