Mediating Factors Associated With Physical Activity in Older Adults at Increased Dementia Risk

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Mediating Factors Associated With Physical Activity in Older Adults at Increased Dementia Risk. / Cardona, Maria Isabel; Luppa, Melanie; Zülke, Andrea; Kroeber, Eric S; Bauer, Alexander; Döhring, Juliane; Escales, Catharina; Brettschneider, Christian; Frese, Thomas; Kosilek, Robert P; Gensichen, Jochen; Hoffmann, Wolfgang; Kaduszkiewicz, Hanna; König, Hans-Helmut; Wiese, Birgitt; Riedel-Heller, Steffi G; Thyrian, Jochen René.

In: AM J ALZHEIMERS DIS, Vol. 39, 2024, p. 15333175241257849.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Cardona, MI, Luppa, M, Zülke, A, Kroeber, ES, Bauer, A, Döhring, J, Escales, C, Brettschneider, C, Frese, T, Kosilek, RP, Gensichen, J, Hoffmann, W, Kaduszkiewicz, H, König, H-H, Wiese, B, Riedel-Heller, SG & Thyrian, JR 2024, 'Mediating Factors Associated With Physical Activity in Older Adults at Increased Dementia Risk', AM J ALZHEIMERS DIS, vol. 39, pp. 15333175241257849. https://doi.org/10.1177/15333175241257849

APA

Cardona, M. I., Luppa, M., Zülke, A., Kroeber, E. S., Bauer, A., Döhring, J., Escales, C., Brettschneider, C., Frese, T., Kosilek, R. P., Gensichen, J., Hoffmann, W., Kaduszkiewicz, H., König, H-H., Wiese, B., Riedel-Heller, S. G., & Thyrian, J. R. (2024). Mediating Factors Associated With Physical Activity in Older Adults at Increased Dementia Risk. AM J ALZHEIMERS DIS, 39, 15333175241257849. https://doi.org/10.1177/15333175241257849

Vancouver

Bibtex

@article{7a680245c23b4a2d9314f9a292a6a160,
title = "Mediating Factors Associated With Physical Activity in Older Adults at Increased Dementia Risk",
abstract = "While regular physical-activity (PA) is beneficial, multimorbid individuals at increased dementia risk may exhibit reduced PA levels. Thus, a more comprehensive understanding of mediating factors responsible for inactivity in this population is needed. This study investigated the impact of a multimodal intervention on PA changes at 24-month follow-up and associated mediating factors among community-dwelling patients aged 60-77, with increased dementia risk determined by the CAIDE Dementia Risk Score. Of 1030 participants recruited, 819 completed the assessment. Thus, a generalized estimating equations model initially assessed differences in PA over 24 months, followed by a tree analysis identifying mediating factors influencing PA changes post-intervention. While no significant effect on regular PA was found during the follow-up (P = .674), subgroup analysis revealed improved self-efficacy (P = .000) associated with increased engagement in PA. Incorporating self-efficacy elements into future strategies is crucial for promoting PA among individuals with multimorbidity and at increased dementia risk.",
keywords = "Humans, Dementia, Male, Female, Aged, Exercise/physiology, Middle Aged, Self Efficacy, Independent Living, Follow-Up Studies, Multimorbidity, Risk Factors",
author = "Cardona, {Maria Isabel} and Melanie Luppa and Andrea Z{\"u}lke and Kroeber, {Eric S} and Alexander Bauer and Juliane D{\"o}hring and Catharina Escales and Christian Brettschneider and Thomas Frese and Kosilek, {Robert P} and Jochen Gensichen and Wolfgang Hoffmann and Hanna Kaduszkiewicz and Hans-Helmut K{\"o}nig and Birgitt Wiese and Riedel-Heller, {Steffi G} and Thyrian, {Jochen Ren{\'e}}",
year = "2024",
doi = "10.1177/15333175241257849",
language = "English",
volume = "39",
pages = "15333175241257849",
journal = "AM J ALZHEIMERS DIS",
issn = "1533-3175",
publisher = "SAGE Publications",

}

RIS

TY - JOUR

T1 - Mediating Factors Associated With Physical Activity in Older Adults at Increased Dementia Risk

AU - Cardona, Maria Isabel

AU - Luppa, Melanie

AU - Zülke, Andrea

AU - Kroeber, Eric S

AU - Bauer, Alexander

AU - Döhring, Juliane

AU - Escales, Catharina

AU - Brettschneider, Christian

AU - Frese, Thomas

AU - Kosilek, Robert P

AU - Gensichen, Jochen

AU - Hoffmann, Wolfgang

AU - Kaduszkiewicz, Hanna

AU - König, Hans-Helmut

AU - Wiese, Birgitt

AU - Riedel-Heller, Steffi G

AU - Thyrian, Jochen René

PY - 2024

Y1 - 2024

N2 - While regular physical-activity (PA) is beneficial, multimorbid individuals at increased dementia risk may exhibit reduced PA levels. Thus, a more comprehensive understanding of mediating factors responsible for inactivity in this population is needed. This study investigated the impact of a multimodal intervention on PA changes at 24-month follow-up and associated mediating factors among community-dwelling patients aged 60-77, with increased dementia risk determined by the CAIDE Dementia Risk Score. Of 1030 participants recruited, 819 completed the assessment. Thus, a generalized estimating equations model initially assessed differences in PA over 24 months, followed by a tree analysis identifying mediating factors influencing PA changes post-intervention. While no significant effect on regular PA was found during the follow-up (P = .674), subgroup analysis revealed improved self-efficacy (P = .000) associated with increased engagement in PA. Incorporating self-efficacy elements into future strategies is crucial for promoting PA among individuals with multimorbidity and at increased dementia risk.

AB - While regular physical-activity (PA) is beneficial, multimorbid individuals at increased dementia risk may exhibit reduced PA levels. Thus, a more comprehensive understanding of mediating factors responsible for inactivity in this population is needed. This study investigated the impact of a multimodal intervention on PA changes at 24-month follow-up and associated mediating factors among community-dwelling patients aged 60-77, with increased dementia risk determined by the CAIDE Dementia Risk Score. Of 1030 participants recruited, 819 completed the assessment. Thus, a generalized estimating equations model initially assessed differences in PA over 24 months, followed by a tree analysis identifying mediating factors influencing PA changes post-intervention. While no significant effect on regular PA was found during the follow-up (P = .674), subgroup analysis revealed improved self-efficacy (P = .000) associated with increased engagement in PA. Incorporating self-efficacy elements into future strategies is crucial for promoting PA among individuals with multimorbidity and at increased dementia risk.

KW - Humans

KW - Dementia

KW - Male

KW - Female

KW - Aged

KW - Exercise/physiology

KW - Middle Aged

KW - Self Efficacy

KW - Independent Living

KW - Follow-Up Studies

KW - Multimorbidity

KW - Risk Factors

U2 - 10.1177/15333175241257849

DO - 10.1177/15333175241257849

M3 - SCORING: Journal article

C2 - 38828622

VL - 39

SP - 15333175241257849

JO - AM J ALZHEIMERS DIS

JF - AM J ALZHEIMERS DIS

SN - 1533-3175

ER -