Measuring patient-relevant benefits in pruritus treatment: development and validation of a specific outcomes tool.
Standard
Measuring patient-relevant benefits in pruritus treatment: development and validation of a specific outcomes tool. / Blome, Christine; Augustin, Matthias; Siepmann, D; Phan, N Q; Rustenbach, Stephan Jeff; Ständer, S.
In: BRIT J DERMATOL, Vol. 161, No. 5, 5, 2009, p. 1143-1148.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Measuring patient-relevant benefits in pruritus treatment: development and validation of a specific outcomes tool.
AU - Blome, Christine
AU - Augustin, Matthias
AU - Siepmann, D
AU - Phan, N Q
AU - Rustenbach, Stephan Jeff
AU - Ständer, S
PY - 2009
Y1 - 2009
N2 - BACKGROUND: The assessment of patient-relevant benefit is gaining importance in evaluating treatments. The 'Patient Benefit Index, standard version' questionnaire (PBI-S) is a validated instrument to assess patients' treatment needs and benefits in skin diseases. Before therapy, the patient rates the importance of predefined treatment goals; after therapy, he rates the extent to which these goals have been achieved. Thus far, no such instrument has been developed specifically for pruritus. OBJECTIVES: Development and validation of a patient-relevant benefit questionnaire in the treatment of pruritus. METHODS: Fifty patients with pruritus were questioned on impairments due to pruritus and treatment needs. Four treatment objectives not already covered by the PBI-S were added to obtain a disease-specific instrument. This was tested for feasibility by 36 patients with pruritus and validated in a sample of 100 patients with pruritus. RESULTS: The instrument was feasible in clinical practice. There were <2% missing values. Cronbach's alpha of the needs questionnaire was 0.93. Convergent validity was demonstrated with respect to reduction of pruritus and quality of life. CONCLUSIONS: The PBI for pruritus is a feasible, reliable and valid instrument that is highly accepted in daily routine for recording patient-reported benefit.
AB - BACKGROUND: The assessment of patient-relevant benefit is gaining importance in evaluating treatments. The 'Patient Benefit Index, standard version' questionnaire (PBI-S) is a validated instrument to assess patients' treatment needs and benefits in skin diseases. Before therapy, the patient rates the importance of predefined treatment goals; after therapy, he rates the extent to which these goals have been achieved. Thus far, no such instrument has been developed specifically for pruritus. OBJECTIVES: Development and validation of a patient-relevant benefit questionnaire in the treatment of pruritus. METHODS: Fifty patients with pruritus were questioned on impairments due to pruritus and treatment needs. Four treatment objectives not already covered by the PBI-S were added to obtain a disease-specific instrument. This was tested for feasibility by 36 patients with pruritus and validated in a sample of 100 patients with pruritus. RESULTS: The instrument was feasible in clinical practice. There were <2% missing values. Cronbach's alpha of the needs questionnaire was 0.93. Convergent validity was demonstrated with respect to reduction of pruritus and quality of life. CONCLUSIONS: The PBI for pruritus is a feasible, reliable and valid instrument that is highly accepted in daily routine for recording patient-reported benefit.
M3 - SCORING: Zeitschriftenaufsatz
VL - 161
SP - 1143
EP - 1148
JO - BRIT J DERMATOL
JF - BRIT J DERMATOL
SN - 0007-0963
IS - 5
M1 - 5
ER -
