Measuring inter-rater reliability for nominal data - which coefficients and confidence intervals are appropriate?

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Measuring inter-rater reliability for nominal data - which coefficients and confidence intervals are appropriate? / Zapf, Antonia; Castell, Stefanie; Morawietz, Lars; Karch, André.

In: BMC MED RES METHODOL, Vol. 16, 05.08.2016, p. 93.

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@article{0103eee783af4bb3af42653dc8c502f2,
title = "Measuring inter-rater reliability for nominal data - which coefficients and confidence intervals are appropriate?",
abstract = "BACKGROUND: Reliability of measurements is a prerequisite of medical research. For nominal data, Fleiss' kappa (in the following labelled as Fleiss' K) and Krippendorff's alpha provide the highest flexibility of the available reliability measures with respect to number of raters and categories. Our aim was to investigate which measures and which confidence intervals provide the best statistical properties for the assessment of inter-rater reliability in different situations.METHODS: We performed a large simulation study to investigate the precision of the estimates for Fleiss' K and Krippendorff's alpha and to determine the empirical coverage probability of the corresponding confidence intervals (asymptotic for Fleiss' K and bootstrap for both measures). Furthermore, we compared measures and confidence intervals in a real world case study.RESULTS: Point estimates of Fleiss' K and Krippendorff's alpha did not differ from each other in all scenarios. In the case of missing data (completely at random), Krippendorff's alpha provided stable estimates, while the complete case analysis approach for Fleiss' K led to biased estimates. For shifted null hypotheses, the coverage probability of the asymptotic confidence interval for Fleiss' K was low, while the bootstrap confidence intervals for both measures provided a coverage probability close to the theoretical one.CONCLUSIONS: Fleiss' K and Krippendorff's alpha with bootstrap confidence intervals are equally suitable for the analysis of reliability of complete nominal data. The asymptotic confidence interval for Fleiss' K should not be used. In the case of missing data or data or higher than nominal order, Krippendorff's alpha is recommended. Together with this article, we provide an R-script for calculating Fleiss' K and Krippendorff's alpha and their corresponding bootstrap confidence intervals.",
keywords = "Algorithms, Breast Neoplasms, Confidence Intervals, Data Interpretation, Statistical, Female, Humans, Observer Variation, Reproducibility of Results, Retrospective Studies, Journal Article",
author = "Antonia Zapf and Stefanie Castell and Lars Morawietz and Andr{\'e} Karch",
year = "2016",
month = aug,
day = "5",
doi = "10.1186/s12874-016-0200-9",
language = "English",
volume = "16",
pages = "93",
journal = "BMC MED RES METHODOL",
issn = "1471-2288",
publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - Measuring inter-rater reliability for nominal data - which coefficients and confidence intervals are appropriate?

AU - Zapf, Antonia

AU - Castell, Stefanie

AU - Morawietz, Lars

AU - Karch, André

PY - 2016/8/5

Y1 - 2016/8/5

N2 - BACKGROUND: Reliability of measurements is a prerequisite of medical research. For nominal data, Fleiss' kappa (in the following labelled as Fleiss' K) and Krippendorff's alpha provide the highest flexibility of the available reliability measures with respect to number of raters and categories. Our aim was to investigate which measures and which confidence intervals provide the best statistical properties for the assessment of inter-rater reliability in different situations.METHODS: We performed a large simulation study to investigate the precision of the estimates for Fleiss' K and Krippendorff's alpha and to determine the empirical coverage probability of the corresponding confidence intervals (asymptotic for Fleiss' K and bootstrap for both measures). Furthermore, we compared measures and confidence intervals in a real world case study.RESULTS: Point estimates of Fleiss' K and Krippendorff's alpha did not differ from each other in all scenarios. In the case of missing data (completely at random), Krippendorff's alpha provided stable estimates, while the complete case analysis approach for Fleiss' K led to biased estimates. For shifted null hypotheses, the coverage probability of the asymptotic confidence interval for Fleiss' K was low, while the bootstrap confidence intervals for both measures provided a coverage probability close to the theoretical one.CONCLUSIONS: Fleiss' K and Krippendorff's alpha with bootstrap confidence intervals are equally suitable for the analysis of reliability of complete nominal data. The asymptotic confidence interval for Fleiss' K should not be used. In the case of missing data or data or higher than nominal order, Krippendorff's alpha is recommended. Together with this article, we provide an R-script for calculating Fleiss' K and Krippendorff's alpha and their corresponding bootstrap confidence intervals.

AB - BACKGROUND: Reliability of measurements is a prerequisite of medical research. For nominal data, Fleiss' kappa (in the following labelled as Fleiss' K) and Krippendorff's alpha provide the highest flexibility of the available reliability measures with respect to number of raters and categories. Our aim was to investigate which measures and which confidence intervals provide the best statistical properties for the assessment of inter-rater reliability in different situations.METHODS: We performed a large simulation study to investigate the precision of the estimates for Fleiss' K and Krippendorff's alpha and to determine the empirical coverage probability of the corresponding confidence intervals (asymptotic for Fleiss' K and bootstrap for both measures). Furthermore, we compared measures and confidence intervals in a real world case study.RESULTS: Point estimates of Fleiss' K and Krippendorff's alpha did not differ from each other in all scenarios. In the case of missing data (completely at random), Krippendorff's alpha provided stable estimates, while the complete case analysis approach for Fleiss' K led to biased estimates. For shifted null hypotheses, the coverage probability of the asymptotic confidence interval for Fleiss' K was low, while the bootstrap confidence intervals for both measures provided a coverage probability close to the theoretical one.CONCLUSIONS: Fleiss' K and Krippendorff's alpha with bootstrap confidence intervals are equally suitable for the analysis of reliability of complete nominal data. The asymptotic confidence interval for Fleiss' K should not be used. In the case of missing data or data or higher than nominal order, Krippendorff's alpha is recommended. Together with this article, we provide an R-script for calculating Fleiss' K and Krippendorff's alpha and their corresponding bootstrap confidence intervals.

KW - Algorithms

KW - Breast Neoplasms

KW - Confidence Intervals

KW - Data Interpretation, Statistical

KW - Female

KW - Humans

KW - Observer Variation

KW - Reproducibility of Results

KW - Retrospective Studies

KW - Journal Article

U2 - 10.1186/s12874-016-0200-9

DO - 10.1186/s12874-016-0200-9

M3 - SCORING: Journal article

C2 - 27495131

VL - 16

SP - 93

JO - BMC MED RES METHODOL

JF - BMC MED RES METHODOL

SN - 1471-2288

ER -