Management of viral hepatitis in patients with haematological malignancy and in patients undergoing haemopoietic stem cell Transplantation: recommendations of the 5th European Conference on Infections in Leukaemia (ECIL-5)
Standard
Management of viral hepatitis in patients with haematological malignancy and in patients undergoing haemopoietic stem cell Transplantation: recommendations of the 5th European Conference on Infections in Leukaemia (ECIL-5). / Mallet, Vincent; van Bömmel, Florian; Doerig, Christopher; Pischke, Sven; Hermine, Olivier; Locasciulli, Anna; Cordonnier, Catherine; Berg, Thomas; Moradpour, Darius; Wedemeyer, Heiner; Ljungman, Per; ECIL-5.
In: LANCET INFECT DIS, Vol. 16, No. 5, 05.2016, p. 606-17.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Management of viral hepatitis in patients with haematological malignancy and in patients undergoing haemopoietic stem cell Transplantation: recommendations of the 5th European Conference on Infections in Leukaemia (ECIL-5)
AU - Mallet, Vincent
AU - van Bömmel, Florian
AU - Doerig, Christopher
AU - Pischke, Sven
AU - Hermine, Olivier
AU - Locasciulli, Anna
AU - Cordonnier, Catherine
AU - Berg, Thomas
AU - Moradpour, Darius
AU - Wedemeyer, Heiner
AU - Ljungman, Per
AU - ECIL-5
N1 - Copyright © 2016 Elsevier Ltd. All rights reserved.
PY - 2016/5
Y1 - 2016/5
N2 - Viral hepatitis affects millions of people worldwide, and host immunity is the key determinant of patient outcome. Viral hepatitis can be life threatening in patients with haematological malignancy, including haemopoietic stem cell transplant recipients, because of the virus itself, or through a need to decrease the dose of chemotherapy. A past or currently infected haemopoietic stem cell donor could also transmit viral hepatitis. The burden of viral hepatitis in patients with haematological malignancies and the weak evidence on which previous guidelines are based has prompted the European Conference on Infection in Leukaemia (ECIL-5) to convene a group of experts in the fields of viral hepatitis and of haematological malignancy to specifically address previously unconsidered issues and grade the available quality of evidence according to the Infectious Diseases Society of America grading system. The group recommends that all patients should be screened for hepatotropic viruses before haematological treatment and that patients or haemopoietic stem cell donors with markers of past or current viral hepatitis should be assessed by an expert. Screening, vaccination, and treatment rules are reported in this Review.
AB - Viral hepatitis affects millions of people worldwide, and host immunity is the key determinant of patient outcome. Viral hepatitis can be life threatening in patients with haematological malignancy, including haemopoietic stem cell transplant recipients, because of the virus itself, or through a need to decrease the dose of chemotherapy. A past or currently infected haemopoietic stem cell donor could also transmit viral hepatitis. The burden of viral hepatitis in patients with haematological malignancies and the weak evidence on which previous guidelines are based has prompted the European Conference on Infection in Leukaemia (ECIL-5) to convene a group of experts in the fields of viral hepatitis and of haematological malignancy to specifically address previously unconsidered issues and grade the available quality of evidence according to the Infectious Diseases Society of America grading system. The group recommends that all patients should be screened for hepatotropic viruses before haematological treatment and that patients or haemopoietic stem cell donors with markers of past or current viral hepatitis should be assessed by an expert. Screening, vaccination, and treatment rules are reported in this Review.
KW - Journal Article
KW - Review
U2 - 10.1016/S1473-3099(16)00118-3
DO - 10.1016/S1473-3099(16)00118-3
M3 - SCORING: Journal article
C2 - 27599653
VL - 16
SP - 606
EP - 617
JO - LANCET INFECT DIS
JF - LANCET INFECT DIS
SN - 1473-3099
IS - 5
ER -