Management of incomplete remission and treatment resistance in first-episode psychosis.
Standard
Management of incomplete remission and treatment resistance in first-episode psychosis. / Lambert, Martin; Naber, Dieter; Huber, Christian.
In: EXPERT OPIN PHARMACO, Vol. 9, No. 12, 12, 2008, p. 2039-2051.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Management of incomplete remission and treatment resistance in first-episode psychosis.
AU - Lambert, Martin
AU - Naber, Dieter
AU - Huber, Christian
PY - 2008
Y1 - 2008
N2 - BACKGROUND: Incomplete remission and treatment resistance are common even in first-episode psychosis patients. OBJECTIVE: The aim of this review was to provide an overview of the available interventions and treatment pathways for the management of incomplete remission and treatment resistance in first-episode psychosis. METHODS: The review undertook a computerized and manual literature search for relevant articles published within recent years. RESULTS: Standard therapy has to be optimized in order to prevent treatment non-response. The early detection strategies of incomplete remission and treatment resistance include re-evaluation of the diagnosis and optimization of pharmacological and non-pharmacological interventions including the treatment of co-morbid disorders. If partial or non-response is confirmed, pharmacological and psychosocial treatment adaptations should be applied stepwise as presented in the current review. Interventions have to be offered in a timely manner because early adaptation of treatment is associated with a greater probability of remission.
AB - BACKGROUND: Incomplete remission and treatment resistance are common even in first-episode psychosis patients. OBJECTIVE: The aim of this review was to provide an overview of the available interventions and treatment pathways for the management of incomplete remission and treatment resistance in first-episode psychosis. METHODS: The review undertook a computerized and manual literature search for relevant articles published within recent years. RESULTS: Standard therapy has to be optimized in order to prevent treatment non-response. The early detection strategies of incomplete remission and treatment resistance include re-evaluation of the diagnosis and optimization of pharmacological and non-pharmacological interventions including the treatment of co-morbid disorders. If partial or non-response is confirmed, pharmacological and psychosocial treatment adaptations should be applied stepwise as presented in the current review. Interventions have to be offered in a timely manner because early adaptation of treatment is associated with a greater probability of remission.
M3 - SCORING: Zeitschriftenaufsatz
VL - 9
SP - 2039
EP - 2051
JO - EXPERT OPIN PHARMACO
JF - EXPERT OPIN PHARMACO
SN - 1465-6566
IS - 12
M1 - 12
ER -
