Magnetic resonance imaging and clinical patterns of patients with 'spectacular shrinking deficit' after acute middle cerebral artery stroke.

Standard

Magnetic resonance imaging and clinical patterns of patients with 'spectacular shrinking deficit' after acute middle cerebral artery stroke. / Kraemer, Nils; Thomalla, Götz; Soennichsen, Jan; Fiehler, Jens; Knab, René; Kucinski, Thomas; Zeumer, Hermann; Rother, Joachim.

In: CEREBROVASC DIS, Vol. 20, No. 5, 5, 2005, p. 285-290.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

APA

Vancouver

Bibtex

@article{8b8849bb7e3849ae8f85641d00653daf,
title = "Magnetic resonance imaging and clinical patterns of patients with 'spectacular shrinking deficit' after acute middle cerebral artery stroke.",
abstract = "BACKGROUND: Rapid resolution of neurological deficits after severe middle cerebral artery (MCA) stroke has been coined spectacular shrinking deficit (SSD). We studied clinical and MRI patterns in patients with SSD. METHODS: Patients with acute MCA stroke or =8-point-reduction of neurological deficit in the National Institute of Health Stroke Scale (NIHSS) to a score of +4 s). Recanalization was assessed by MRA after 24 h. Final infarct volumes were defined on T2 weighted images at day seven. Outcome was assessed after 90 days using modified Rankin Scale (mRS) and Barthel Index (BI). RESULTS: SSD was present in 14 of 104 patients. Initial DWI and PWI lesion volumes were smaller in SSD patients - ADC <80%: 8.9 (4.3-20.5) vs. 30 (0-266.7) ml; TTP > +4 s: 91.6 (29.7-205.8) vs. 131.5 (0-311.5) ml. Early recanalization was associated with SSD resulted in smaller final infarct volumes (11.9 (2.4-25.9) vs. 47.7 (1.2-288.5)). All SSD patients were independent at day 90 (mRS 0 (0-2); BI 100). CONCLUSION: The clinical syndrome of SSD is reflected by a typical MRI pattern with small initial DWI and PWI lesion volumes, timely recanalization and small final infarct volumes.",
author = "Nils Kraemer and G{\"o}tz Thomalla and Jan Soennichsen and Jens Fiehler and Ren{\'e} Knab and Thomas Kucinski and Hermann Zeumer and Joachim Rother",
year = "2005",
language = "Deutsch",
volume = "20",
pages = "285--290",
journal = "CEREBROVASC DIS",
issn = "1015-9770",
publisher = "S. Karger AG",
number = "5",

}

RIS

TY - JOUR

T1 - Magnetic resonance imaging and clinical patterns of patients with 'spectacular shrinking deficit' after acute middle cerebral artery stroke.

AU - Kraemer, Nils

AU - Thomalla, Götz

AU - Soennichsen, Jan

AU - Fiehler, Jens

AU - Knab, René

AU - Kucinski, Thomas

AU - Zeumer, Hermann

AU - Rother, Joachim

PY - 2005

Y1 - 2005

N2 - BACKGROUND: Rapid resolution of neurological deficits after severe middle cerebral artery (MCA) stroke has been coined spectacular shrinking deficit (SSD). We studied clinical and MRI patterns in patients with SSD. METHODS: Patients with acute MCA stroke or =8-point-reduction of neurological deficit in the National Institute of Health Stroke Scale (NIHSS) to a score of +4 s). Recanalization was assessed by MRA after 24 h. Final infarct volumes were defined on T2 weighted images at day seven. Outcome was assessed after 90 days using modified Rankin Scale (mRS) and Barthel Index (BI). RESULTS: SSD was present in 14 of 104 patients. Initial DWI and PWI lesion volumes were smaller in SSD patients - ADC <80%: 8.9 (4.3-20.5) vs. 30 (0-266.7) ml; TTP > +4 s: 91.6 (29.7-205.8) vs. 131.5 (0-311.5) ml. Early recanalization was associated with SSD resulted in smaller final infarct volumes (11.9 (2.4-25.9) vs. 47.7 (1.2-288.5)). All SSD patients were independent at day 90 (mRS 0 (0-2); BI 100). CONCLUSION: The clinical syndrome of SSD is reflected by a typical MRI pattern with small initial DWI and PWI lesion volumes, timely recanalization and small final infarct volumes.

AB - BACKGROUND: Rapid resolution of neurological deficits after severe middle cerebral artery (MCA) stroke has been coined spectacular shrinking deficit (SSD). We studied clinical and MRI patterns in patients with SSD. METHODS: Patients with acute MCA stroke or =8-point-reduction of neurological deficit in the National Institute of Health Stroke Scale (NIHSS) to a score of +4 s). Recanalization was assessed by MRA after 24 h. Final infarct volumes were defined on T2 weighted images at day seven. Outcome was assessed after 90 days using modified Rankin Scale (mRS) and Barthel Index (BI). RESULTS: SSD was present in 14 of 104 patients. Initial DWI and PWI lesion volumes were smaller in SSD patients - ADC <80%: 8.9 (4.3-20.5) vs. 30 (0-266.7) ml; TTP > +4 s: 91.6 (29.7-205.8) vs. 131.5 (0-311.5) ml. Early recanalization was associated with SSD resulted in smaller final infarct volumes (11.9 (2.4-25.9) vs. 47.7 (1.2-288.5)). All SSD patients were independent at day 90 (mRS 0 (0-2); BI 100). CONCLUSION: The clinical syndrome of SSD is reflected by a typical MRI pattern with small initial DWI and PWI lesion volumes, timely recanalization and small final infarct volumes.

M3 - SCORING: Zeitschriftenaufsatz

VL - 20

SP - 285

EP - 290

JO - CEREBROVASC DIS

JF - CEREBROVASC DIS

SN - 1015-9770

IS - 5

M1 - 5

ER -