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Lys-plasminogen as an adjunct to local intra-arterial fibrinolysis for carotid territory stroke: laboratory and clinical findings.

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Lys-plasminogen as an adjunct to local intra-arterial fibrinolysis for carotid territory stroke: laboratory and clinical findings. / Freitag, H J; Becker, V U; Thie, A; Tilsner, V; Philapitsch, A; Schwarz, H P; Webhof, U; Müller, A; Zeumer, Hermann.

In: NEURORADIOLOGY, Vol. 38, No. 2, 2, 1996, p. 181-185.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Freitag, HJ, Becker, VU, Thie, A, Tilsner, V, Philapitsch, A, Schwarz, HP, Webhof, U, Müller, A & Zeumer, H 1996, 'Lys-plasminogen as an adjunct to local intra-arterial fibrinolysis for carotid territory stroke: laboratory and clinical findings.', NEURORADIOLOGY, vol. 38, no. 2, 2, pp. 181-185. <http://www.ncbi.nlm.nih.gov/pubmed/8692437?dopt=Citation>

APA

Freitag, H. J., Becker, V. U., Thie, A., Tilsner, V., Philapitsch, A., Schwarz, H. P., Webhof, U., Müller, A., & Zeumer, H. (1996). Lys-plasminogen as an adjunct to local intra-arterial fibrinolysis for carotid territory stroke: laboratory and clinical findings. NEURORADIOLOGY, 38(2), 181-185. [2]. http://www.ncbi.nlm.nih.gov/pubmed/8692437?dopt=Citation

Vancouver

Freitag HJ, Becker VU, Thie A, Tilsner V, Philapitsch A, Schwarz HP et al. Lys-plasminogen as an adjunct to local intra-arterial fibrinolysis for carotid territory stroke: laboratory and clinical findings. NEURORADIOLOGY. 1996;38(2):181-185. 2.

Bibtex

@article{7ba252a339cb4b8c80562681a2e492fc,
title = "Lys-plasminogen as an adjunct to local intra-arterial fibrinolysis for carotid territory stroke: laboratory and clinical findings.",
abstract = "To improve the efficacy of local intraarterial fibrinolysis (LIF), we compared different fibrinolytic drugs in a cerebral circulation model in the laboratory. The technical efficacy of fibrinolysis, defined as the clot volume lysed per unit time, was found to be optimal with r-tissue plasminogen activator (TPA) activated lys-plasminogen (= plasmin). Subsequently, 20 patients with stroke due to carotid artery territory occlusion were treated by local intraarterial fibrinolysis using the plasmin regimen. The angiographic data and clinical outcome of these patients were compared with those of 40 patients who received plasminogen activators (urokinase or r-TPA) only. Laboratory and clinical data confirmed that plasmin lysis is superior to treatment using only plasminogen activators.",
author = "Freitag, {H J} and Becker, {V U} and A Thie and V Tilsner and A Philapitsch and Schwarz, {H P} and U Webhof and A M{\"u}ller and Hermann Zeumer",
year = "1996",
language = "Deutsch",
volume = "38",
pages = "181--185",
journal = "NEURORADIOLOGY",
issn = "0028-3940",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Lys-plasminogen as an adjunct to local intra-arterial fibrinolysis for carotid territory stroke: laboratory and clinical findings.

AU - Freitag, H J

AU - Becker, V U

AU - Thie, A

AU - Tilsner, V

AU - Philapitsch, A

AU - Schwarz, H P

AU - Webhof, U

AU - Müller, A

AU - Zeumer, Hermann

PY - 1996

Y1 - 1996

N2 - To improve the efficacy of local intraarterial fibrinolysis (LIF), we compared different fibrinolytic drugs in a cerebral circulation model in the laboratory. The technical efficacy of fibrinolysis, defined as the clot volume lysed per unit time, was found to be optimal with r-tissue plasminogen activator (TPA) activated lys-plasminogen (= plasmin). Subsequently, 20 patients with stroke due to carotid artery territory occlusion were treated by local intraarterial fibrinolysis using the plasmin regimen. The angiographic data and clinical outcome of these patients were compared with those of 40 patients who received plasminogen activators (urokinase or r-TPA) only. Laboratory and clinical data confirmed that plasmin lysis is superior to treatment using only plasminogen activators.

AB - To improve the efficacy of local intraarterial fibrinolysis (LIF), we compared different fibrinolytic drugs in a cerebral circulation model in the laboratory. The technical efficacy of fibrinolysis, defined as the clot volume lysed per unit time, was found to be optimal with r-tissue plasminogen activator (TPA) activated lys-plasminogen (= plasmin). Subsequently, 20 patients with stroke due to carotid artery territory occlusion were treated by local intraarterial fibrinolysis using the plasmin regimen. The angiographic data and clinical outcome of these patients were compared with those of 40 patients who received plasminogen activators (urokinase or r-TPA) only. Laboratory and clinical data confirmed that plasmin lysis is superior to treatment using only plasminogen activators.

M3 - SCORING: Zeitschriftenaufsatz

VL - 38

SP - 181

EP - 185

JO - NEURORADIOLOGY

JF - NEURORADIOLOGY

SN - 0028-3940

IS - 2

M1 - 2

ER -