Lung function decline in 4-monthly repeated spirometric measurements: due to silt aerosol exposure or decreasing effort?

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Lung function decline in 4-monthly repeated spirometric measurements: due to silt aerosol exposure or decreasing effort? / Radon, K; Wegner, Ralf; Szadkowski, D.

In: RESPIRATION, Vol. 67, No. 1, 1, 2000, p. 41-45.

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@article{ced64237d1614dcc937744b9bb8c19e4,
title = "Lung function decline in 4-monthly repeated spirometric measurements: due to silt aerosol exposure or decreasing effort?",
abstract = "BACKGROUND: Workers on dredgers and lighters on rivers are exposed to the inhalation of aerosols and dusts. OBJECTIVE: The aim of this study was to investigate effects of river silt aerosol and dust exposure on the respiratory health of dredging employees. METHODS: Six examinations were performed over a period of 2 years at 4-monthly intervals in 54 seamen with higher silt aerosol exposure and 36 controls of the same employer. RESULTS: No significant differences could be observed between the groups at any time of the study but there was an unexpected significant decrease in the age-corrected expiratory vital capacity (FVC), forced expiratory volume in 1 s (FEV(1)) and midexpiratory flow rate (MMEF(25/75)) over the six series in both groups. This may indicate a loss of effort of the participants in re-examinations since biological and technical influences were highly unlikely to be the cause of these findings. CONCLUSIONS: Ignoring this possible decline of effort in frequently repeated measurements may result in overestimating potential effects of occupational exposure.",
author = "K Radon and Ralf Wegner and D Szadkowski",
year = "2000",
language = "Deutsch",
volume = "67",
pages = "41--45",
journal = "RESPIRATION",
issn = "0025-7931",
publisher = "S. Karger AG",
number = "1",

}

RIS

TY - JOUR

T1 - Lung function decline in 4-monthly repeated spirometric measurements: due to silt aerosol exposure or decreasing effort?

AU - Radon, K

AU - Wegner, Ralf

AU - Szadkowski, D

PY - 2000

Y1 - 2000

N2 - BACKGROUND: Workers on dredgers and lighters on rivers are exposed to the inhalation of aerosols and dusts. OBJECTIVE: The aim of this study was to investigate effects of river silt aerosol and dust exposure on the respiratory health of dredging employees. METHODS: Six examinations were performed over a period of 2 years at 4-monthly intervals in 54 seamen with higher silt aerosol exposure and 36 controls of the same employer. RESULTS: No significant differences could be observed between the groups at any time of the study but there was an unexpected significant decrease in the age-corrected expiratory vital capacity (FVC), forced expiratory volume in 1 s (FEV(1)) and midexpiratory flow rate (MMEF(25/75)) over the six series in both groups. This may indicate a loss of effort of the participants in re-examinations since biological and technical influences were highly unlikely to be the cause of these findings. CONCLUSIONS: Ignoring this possible decline of effort in frequently repeated measurements may result in overestimating potential effects of occupational exposure.

AB - BACKGROUND: Workers on dredgers and lighters on rivers are exposed to the inhalation of aerosols and dusts. OBJECTIVE: The aim of this study was to investigate effects of river silt aerosol and dust exposure on the respiratory health of dredging employees. METHODS: Six examinations were performed over a period of 2 years at 4-monthly intervals in 54 seamen with higher silt aerosol exposure and 36 controls of the same employer. RESULTS: No significant differences could be observed between the groups at any time of the study but there was an unexpected significant decrease in the age-corrected expiratory vital capacity (FVC), forced expiratory volume in 1 s (FEV(1)) and midexpiratory flow rate (MMEF(25/75)) over the six series in both groups. This may indicate a loss of effort of the participants in re-examinations since biological and technical influences were highly unlikely to be the cause of these findings. CONCLUSIONS: Ignoring this possible decline of effort in frequently repeated measurements may result in overestimating potential effects of occupational exposure.

M3 - SCORING: Zeitschriftenaufsatz

VL - 67

SP - 41

EP - 45

JO - RESPIRATION

JF - RESPIRATION

SN - 0025-7931

IS - 1

M1 - 1

ER -