Lung function decline in 4-monthly repeated spirometric measurements: due to silt aerosol exposure or decreasing effort?
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Lung function decline in 4-monthly repeated spirometric measurements: due to silt aerosol exposure or decreasing effort? / Radon, K; Wegner, Ralf; Szadkowski, D.
In: RESPIRATION, Vol. 67, No. 1, 1, 2000, p. 41-45.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Lung function decline in 4-monthly repeated spirometric measurements: due to silt aerosol exposure or decreasing effort?
AU - Radon, K
AU - Wegner, Ralf
AU - Szadkowski, D
PY - 2000
Y1 - 2000
N2 - BACKGROUND: Workers on dredgers and lighters on rivers are exposed to the inhalation of aerosols and dusts. OBJECTIVE: The aim of this study was to investigate effects of river silt aerosol and dust exposure on the respiratory health of dredging employees. METHODS: Six examinations were performed over a period of 2 years at 4-monthly intervals in 54 seamen with higher silt aerosol exposure and 36 controls of the same employer. RESULTS: No significant differences could be observed between the groups at any time of the study but there was an unexpected significant decrease in the age-corrected expiratory vital capacity (FVC), forced expiratory volume in 1 s (FEV(1)) and midexpiratory flow rate (MMEF(25/75)) over the six series in both groups. This may indicate a loss of effort of the participants in re-examinations since biological and technical influences were highly unlikely to be the cause of these findings. CONCLUSIONS: Ignoring this possible decline of effort in frequently repeated measurements may result in overestimating potential effects of occupational exposure.
AB - BACKGROUND: Workers on dredgers and lighters on rivers are exposed to the inhalation of aerosols and dusts. OBJECTIVE: The aim of this study was to investigate effects of river silt aerosol and dust exposure on the respiratory health of dredging employees. METHODS: Six examinations were performed over a period of 2 years at 4-monthly intervals in 54 seamen with higher silt aerosol exposure and 36 controls of the same employer. RESULTS: No significant differences could be observed between the groups at any time of the study but there was an unexpected significant decrease in the age-corrected expiratory vital capacity (FVC), forced expiratory volume in 1 s (FEV(1)) and midexpiratory flow rate (MMEF(25/75)) over the six series in both groups. This may indicate a loss of effort of the participants in re-examinations since biological and technical influences were highly unlikely to be the cause of these findings. CONCLUSIONS: Ignoring this possible decline of effort in frequently repeated measurements may result in overestimating potential effects of occupational exposure.
M3 - SCORING: Zeitschriftenaufsatz
VL - 67
SP - 41
EP - 45
JO - RESPIRATION
JF - RESPIRATION
SN - 0025-7931
IS - 1
M1 - 1
ER -