Research ExplorerPublicationsLow-dose fixed-target serial synchrotron crystallography

Low-dose fixed-target serial synchrotron crystallography

Standard

Low-dose fixed-target serial synchrotron crystallography. / Owen, Robin L; Axford, Danny; Sherrell, Darren A; Kuo, Anling; Ernst, Oliver P; Schulz, Eike C; Miller, R J Dwayne; Mueller-Werkmeister, Henrike M.

In: ACTA CRYSTALLOGR D, Vol. 73, No. Pt 4, 01.04.2017, p. 373-378.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Owen, RL, Axford, D, Sherrell, DA, Kuo, A, Ernst, OP, Schulz, EC, Miller, RJD & Mueller-Werkmeister, HM 2017, 'Low-dose fixed-target serial synchrotron crystallography', ACTA CRYSTALLOGR D, vol. 73, no. Pt 4, pp. 373-378. https://doi.org/10.1107/S2059798317002996

APA

Owen, R. L., Axford, D., Sherrell, D. A., Kuo, A., Ernst, O. P., Schulz, E. C., Miller, R. J. D., & Mueller-Werkmeister, H. M. (2017). Low-dose fixed-target serial synchrotron crystallography. ACTA CRYSTALLOGR D, 73(Pt 4), 373-378. https://doi.org/10.1107/S2059798317002996

Vancouver

Owen RL, Axford D, Sherrell DA, Kuo A, Ernst OP, Schulz EC et al. Low-dose fixed-target serial synchrotron crystallography. ACTA CRYSTALLOGR D. 2017 Apr 1;73(Pt 4):373-378. https://doi.org/10.1107/S2059798317002996

Bibtex

@article{f8f3a124c68a4a6786e17aeed8028d67,
title = "Low-dose fixed-target serial synchrotron crystallography",
abstract = "The development of serial crystallography has been driven by the sample requirements imposed by X-ray free-electron lasers. Serial techniques are now being exploited at synchrotrons. Using a fixed-target approach to high-throughput serial sampling, it is demonstrated that high-quality data can be collected from myoglobin crystals, allowing room-temperature, low-dose structure determination. The combination of fixed-target arrays and a fast, accurate translation system allows high-throughput serial data collection at high hit rates and with low sample consumption.",
keywords = "Animals, Crystallization/instrumentation, Crystallography, X-Ray/instrumentation, Equipment Design, Lab-On-A-Chip Devices, Models, Molecular, Myoglobin/chemistry, Sperm Whale, Synchrotrons",
author = "Owen, {Robin L} and Danny Axford and Sherrell, {Darren A} and Anling Kuo and Ernst, {Oliver P} and Schulz, {Eike C} and Miller, {R J Dwayne} and Mueller-Werkmeister, {Henrike M}",
year = "2017",
month = apr,
day = "1",
doi = "10.1107/S2059798317002996",
language = "English",
volume = "73",
pages = "373--378",
journal = "ACTA CRYSTALLOGR D",
issn = "2059-7983",
publisher = "John Wiley and Sons Inc.",
number = "Pt 4",

}

RIS

TY - JOUR

T1 - Low-dose fixed-target serial synchrotron crystallography

AU - Owen, Robin L

AU - Axford, Danny

AU - Sherrell, Darren A

AU - Kuo, Anling

AU - Ernst, Oliver P

AU - Schulz, Eike C

AU - Miller, R J Dwayne

AU - Mueller-Werkmeister, Henrike M

PY - 2017/4/1

Y1 - 2017/4/1

N2 - The development of serial crystallography has been driven by the sample requirements imposed by X-ray free-electron lasers. Serial techniques are now being exploited at synchrotrons. Using a fixed-target approach to high-throughput serial sampling, it is demonstrated that high-quality data can be collected from myoglobin crystals, allowing room-temperature, low-dose structure determination. The combination of fixed-target arrays and a fast, accurate translation system allows high-throughput serial data collection at high hit rates and with low sample consumption.

AB - The development of serial crystallography has been driven by the sample requirements imposed by X-ray free-electron lasers. Serial techniques are now being exploited at synchrotrons. Using a fixed-target approach to high-throughput serial sampling, it is demonstrated that high-quality data can be collected from myoglobin crystals, allowing room-temperature, low-dose structure determination. The combination of fixed-target arrays and a fast, accurate translation system allows high-throughput serial data collection at high hit rates and with low sample consumption.

KW - Animals

KW - Crystallization/instrumentation

KW - Crystallography, X-Ray/instrumentation

KW - Equipment Design

KW - Lab-On-A-Chip Devices

KW - Models, Molecular

KW - Myoglobin/chemistry

KW - Sperm Whale

KW - Synchrotrons

U2 - 10.1107/S2059798317002996

DO - 10.1107/S2059798317002996

M3 - SCORING: Journal article

C2 - 28375148

VL - 73

SP - 373

EP - 378

JO - ACTA CRYSTALLOGR D

JF - ACTA CRYSTALLOGR D

SN - 2059-7983

IS - Pt 4

ER -