Research ExplorerPublicationsLoss of heterozygosity in tumor cells of a recurrent mandibu...

Loss of heterozygosity in tumor cells of a recurrent mandibular giant cell granuloma in neurofibromatosis type 1.

Standard

Loss of heterozygosity in tumor cells of a recurrent mandibular giant cell granuloma in neurofibromatosis type 1. / Friedrich, Reinhard; Mautner, Viktor Felix; Scheuer, Hanna A.

In: ANTICANCER RES, Vol. 27, No. 4, 4, 2007, p. 2079-2083.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Friedrich, R, Mautner, VF & Scheuer, HA 2007, 'Loss of heterozygosity in tumor cells of a recurrent mandibular giant cell granuloma in neurofibromatosis type 1.', ANTICANCER RES, vol. 27, no. 4, 4, pp. 2079-2083. <http://www.ncbi.nlm.nih.gov/pubmed/17649825?dopt=Citation>

APA

Friedrich, R., Mautner, V. F., & Scheuer, H. A. (2007). Loss of heterozygosity in tumor cells of a recurrent mandibular giant cell granuloma in neurofibromatosis type 1. ANTICANCER RES, 27(4), 2079-2083. [4]. http://www.ncbi.nlm.nih.gov/pubmed/17649825?dopt=Citation

Vancouver

Friedrich R, Mautner VF, Scheuer HA. Loss of heterozygosity in tumor cells of a recurrent mandibular giant cell granuloma in neurofibromatosis type 1. ANTICANCER RES. 2007;27(4):2079-2083. 4.

Bibtex

@article{fbcded05a28444e7a4476906be0cd3f0,
title = "Loss of heterozygosity in tumor cells of a recurrent mandibular giant cell granuloma in neurofibromatosis type 1.",
abstract = "Neurofibromatosis type 1 (NF1) is an autosomal dominant inherited disease affecting about 1:3000 humans. Neurofibromas are benign soft tissue tumors. Giant cell granuloma (GCG) is a benign tumor-like lesion that is preferentially located in the jaws. GCG can develop in NF1 patients. A 7-year-old female NF1 patient was successfully treated for a recurrent GCG of the right mandibular premolar region. The serum levels of calcium and phosphate, alkaline phosphatase and parathormone were within the normal range. Genetic analysis of the tumor sample (GCG) and blood using 7 microsatellite markers revealed LOH of the NF1 gene in both sources. Inactivation of the NF1 gene may thus contribute to the development of GCG.",
author = "Reinhard Friedrich and Mautner, {Viktor Felix} and Scheuer, {Hanna A}",
year = "2007",
language = "Deutsch",
volume = "27",
pages = "2079--2083",
journal = "ANTICANCER RES",
issn = "0250-7005",
publisher = "International Institute of Anticancer Research",
number = "4",

}

RIS

TY - JOUR

T1 - Loss of heterozygosity in tumor cells of a recurrent mandibular giant cell granuloma in neurofibromatosis type 1.

AU - Friedrich, Reinhard

AU - Mautner, Viktor Felix

AU - Scheuer, Hanna A

PY - 2007

Y1 - 2007

N2 - Neurofibromatosis type 1 (NF1) is an autosomal dominant inherited disease affecting about 1:3000 humans. Neurofibromas are benign soft tissue tumors. Giant cell granuloma (GCG) is a benign tumor-like lesion that is preferentially located in the jaws. GCG can develop in NF1 patients. A 7-year-old female NF1 patient was successfully treated for a recurrent GCG of the right mandibular premolar region. The serum levels of calcium and phosphate, alkaline phosphatase and parathormone were within the normal range. Genetic analysis of the tumor sample (GCG) and blood using 7 microsatellite markers revealed LOH of the NF1 gene in both sources. Inactivation of the NF1 gene may thus contribute to the development of GCG.

AB - Neurofibromatosis type 1 (NF1) is an autosomal dominant inherited disease affecting about 1:3000 humans. Neurofibromas are benign soft tissue tumors. Giant cell granuloma (GCG) is a benign tumor-like lesion that is preferentially located in the jaws. GCG can develop in NF1 patients. A 7-year-old female NF1 patient was successfully treated for a recurrent GCG of the right mandibular premolar region. The serum levels of calcium and phosphate, alkaline phosphatase and parathormone were within the normal range. Genetic analysis of the tumor sample (GCG) and blood using 7 microsatellite markers revealed LOH of the NF1 gene in both sources. Inactivation of the NF1 gene may thus contribute to the development of GCG.

M3 - SCORING: Zeitschriftenaufsatz

VL - 27

SP - 2079

EP - 2083

JO - ANTICANCER RES

JF - ANTICANCER RES

SN - 0250-7005

IS - 4

M1 - 4

ER -