Long-term outcome in children with relapsed acute lymphoblastic leukemia after time-point and site-of-relapse stratification and intensified short-course multidrug chemotherapy: results of trial ALL-REZ BFM 90.

  • Gesche Tallen
  • Richard Ratei
  • Georg Mann
  • Gertjan Kaspers
  • Felix Niggli
  • Alexandr Karachunsky
  • Wolfram Ebell
  • Gabriele Escherich
  • Martin Schrappe
  • Thomas Klingebiel
  • Ruediger Fengler
  • Günter Henze
  • Arend von Stackelberg

Abstract

The multicenter trial ALL-REZ BFM (ie, Acute Lymphoblastic Leukemia Relapse Berlin-Frankfurt-Münster) 90 was designed to improve prognosis for children with relapsed acute lymphoblastic leukemia (ALL) by time-to-relapse- and site-of-relapse-adapted stratification and by introduction of novel chemotherapy elements and to evaluate new prognostic parameters in a large, population-based cohort.

Bibliographical data

Original languageGerman
Article number14
ISSN0732-183X
Publication statusPublished - 2010
pubmed 20385996