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Long-term neurodevelopmental outcome of 167 children after intrauterine laser treatment for severe twin-twin transfusion syndrome.

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Long-term neurodevelopmental outcome of 167 children after intrauterine laser treatment for severe twin-twin transfusion syndrome. / Graef, Cornelia; Ellenrieder, Birte; Hecher, Kurt; Hackeloer, Bernhard J; Huber, Agnes; Bartmann, Peter.

In: AM J OBSTET GYNECOL, Vol. 194, No. 2, 2, 2006, p. 303-308.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Graef, C, Ellenrieder, B, Hecher, K, Hackeloer, BJ, Huber, A & Bartmann, P 2006, 'Long-term neurodevelopmental outcome of 167 children after intrauterine laser treatment for severe twin-twin transfusion syndrome.', AM J OBSTET GYNECOL, vol. 194, no. 2, 2, pp. 303-308. <http://www.ncbi.nlm.nih.gov/pubmed/16458621?dopt=Citation>

APA

Graef, C., Ellenrieder, B., Hecher, K., Hackeloer, B. J., Huber, A., & Bartmann, P. (2006). Long-term neurodevelopmental outcome of 167 children after intrauterine laser treatment for severe twin-twin transfusion syndrome. AM J OBSTET GYNECOL, 194(2), 303-308. [2]. http://www.ncbi.nlm.nih.gov/pubmed/16458621?dopt=Citation

Vancouver

Graef C, Ellenrieder B, Hecher K, Hackeloer BJ, Huber A, Bartmann P. Long-term neurodevelopmental outcome of 167 children after intrauterine laser treatment for severe twin-twin transfusion syndrome. AM J OBSTET GYNECOL. 2006;194(2):303-308. 2.

Bibtex

@article{0f59f05b227c43b3ab408b49e3a30882,
title = "Long-term neurodevelopmental outcome of 167 children after intrauterine laser treatment for severe twin-twin transfusion syndrome.",
abstract = "OBJECTIVE: This study was undertaken to investigate long-term neurodevelopmental outcome of children born after intrauterine laser coagulation for severe twin-twin transfusion syndrome. STUDY DESIGN: One hundred sixty-seven surviving infants treated between June 1997 and September 1999 were investigated at a median age of 3 years and 2 months. All children underwent a detailed standardized physical and neurologic examination and a standardized developmental test (Griffiths' Developmental Test Scales and Snijders-Oomen Non-Verbal-Intelligence Test). RESULTS: One hundred forty-five infants (86.8%) showed normal development, 12 infants (7.2%) showed minor neurologic abnormalities, and 10 infants (6.0%) major neurologic abnormalities. There was no difference in outcome for the former donors/recipients (P = .349) and between infants who were born as twins or singletons (P = .088). CONCLUSION: With a high rate (86.8%) of normal neurodevelopmental outcome and an incidence of only 6.0% of major neurologic deficiencies, intrauterine laser coagulation seems to be the best treatment option for severe twin-twin transfusion syndrome.",
author = "Cornelia Graef and Birte Ellenrieder and Kurt Hecher and Hackeloer, {Bernhard J} and Agnes Huber and Peter Bartmann",
year = "2006",
language = "Deutsch",
volume = "194",
pages = "303--308",
journal = "AM J OBSTET GYNECOL",
issn = "0002-9378",
publisher = "Mosby Inc.",
number = "2",

}

RIS

TY - JOUR

T1 - Long-term neurodevelopmental outcome of 167 children after intrauterine laser treatment for severe twin-twin transfusion syndrome.

AU - Graef, Cornelia

AU - Ellenrieder, Birte

AU - Hecher, Kurt

AU - Hackeloer, Bernhard J

AU - Huber, Agnes

AU - Bartmann, Peter

PY - 2006

Y1 - 2006

N2 - OBJECTIVE: This study was undertaken to investigate long-term neurodevelopmental outcome of children born after intrauterine laser coagulation for severe twin-twin transfusion syndrome. STUDY DESIGN: One hundred sixty-seven surviving infants treated between June 1997 and September 1999 were investigated at a median age of 3 years and 2 months. All children underwent a detailed standardized physical and neurologic examination and a standardized developmental test (Griffiths' Developmental Test Scales and Snijders-Oomen Non-Verbal-Intelligence Test). RESULTS: One hundred forty-five infants (86.8%) showed normal development, 12 infants (7.2%) showed minor neurologic abnormalities, and 10 infants (6.0%) major neurologic abnormalities. There was no difference in outcome for the former donors/recipients (P = .349) and between infants who were born as twins or singletons (P = .088). CONCLUSION: With a high rate (86.8%) of normal neurodevelopmental outcome and an incidence of only 6.0% of major neurologic deficiencies, intrauterine laser coagulation seems to be the best treatment option for severe twin-twin transfusion syndrome.

AB - OBJECTIVE: This study was undertaken to investigate long-term neurodevelopmental outcome of children born after intrauterine laser coagulation for severe twin-twin transfusion syndrome. STUDY DESIGN: One hundred sixty-seven surviving infants treated between June 1997 and September 1999 were investigated at a median age of 3 years and 2 months. All children underwent a detailed standardized physical and neurologic examination and a standardized developmental test (Griffiths' Developmental Test Scales and Snijders-Oomen Non-Verbal-Intelligence Test). RESULTS: One hundred forty-five infants (86.8%) showed normal development, 12 infants (7.2%) showed minor neurologic abnormalities, and 10 infants (6.0%) major neurologic abnormalities. There was no difference in outcome for the former donors/recipients (P = .349) and between infants who were born as twins or singletons (P = .088). CONCLUSION: With a high rate (86.8%) of normal neurodevelopmental outcome and an incidence of only 6.0% of major neurologic deficiencies, intrauterine laser coagulation seems to be the best treatment option for severe twin-twin transfusion syndrome.

M3 - SCORING: Zeitschriftenaufsatz

VL - 194

SP - 303

EP - 308

JO - AM J OBSTET GYNECOL

JF - AM J OBSTET GYNECOL

SN - 0002-9378

IS - 2

M1 - 2

ER -