Long-term experience with AutoCapture-controlled epicardial pacing in children
Standard
Long-term experience with AutoCapture-controlled epicardial pacing in children. / Tomaske, Maren; Harpes, Paul; Pretre, Rene; Dodge-Khatami, Ali; Bauersfeld, Urs.
In: EUROPACE, Vol. 9, No. 8, 08.2007, p. 645-650.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Long-term experience with AutoCapture-controlled epicardial pacing in children
AU - Tomaske, Maren
AU - Harpes, Paul
AU - Pretre, Rene
AU - Dodge-Khatami, Ali
AU - Bauersfeld, Urs
PY - 2007/8
Y1 - 2007/8
N2 - AIMS: To examine the feasibility and safety of AutoCapture (AC)-controlled pacing with epicardial leads in children, and study the effects on device longevity.METHODS: A total of 62 children were prospectively enrolled. Pre-discharge testing precluded AC function in six children. In 56 (90%) children, devices with AC-controlled pacing were followed up to 9years. Calculated battery life in AC-controlled pacing was compared with theoretical calculations, using a two-fold stimulation output of measured thresholds.RESULTS: In 53 of 56 children, no differences were observed for evoked response signals (13.3 vs. 11.5mV, P = 0.20) or lead polarization safety margins (5.5 vs. 4.1, P = 0.25) at 6-month and 4-year follow-up. A crossover to conventional pacing was required in 3 of 56 children. AC-controlled pacing prolonged the calculated battery life up to 15% for the identity and integrity devices with 0.95A h capacity, compared with theoretical conventional settings (P = 0.008). In patients with ventricular pacing thresholds >1.5V at 0.5ms, battery life was increased by 30% compared with theoretical conventional settings (P < 0.001).CONCLUSION: AC-controlled pacing with epicardial leads is feasible and safe in children during long-term follow-up. An adequate lead polarization safety margin persists in most patients. Calculated battery life was prolonged up to 15% with AC-controlled pacing. Patients with high or fluctuating pacing thresholds benefit the most.
AB - AIMS: To examine the feasibility and safety of AutoCapture (AC)-controlled pacing with epicardial leads in children, and study the effects on device longevity.METHODS: A total of 62 children were prospectively enrolled. Pre-discharge testing precluded AC function in six children. In 56 (90%) children, devices with AC-controlled pacing were followed up to 9years. Calculated battery life in AC-controlled pacing was compared with theoretical calculations, using a two-fold stimulation output of measured thresholds.RESULTS: In 53 of 56 children, no differences were observed for evoked response signals (13.3 vs. 11.5mV, P = 0.20) or lead polarization safety margins (5.5 vs. 4.1, P = 0.25) at 6-month and 4-year follow-up. A crossover to conventional pacing was required in 3 of 56 children. AC-controlled pacing prolonged the calculated battery life up to 15% for the identity and integrity devices with 0.95A h capacity, compared with theoretical conventional settings (P = 0.008). In patients with ventricular pacing thresholds >1.5V at 0.5ms, battery life was increased by 30% compared with theoretical conventional settings (P < 0.001).CONCLUSION: AC-controlled pacing with epicardial leads is feasible and safe in children during long-term follow-up. An adequate lead polarization safety margin persists in most patients. Calculated battery life was prolonged up to 15% with AC-controlled pacing. Patients with high or fluctuating pacing thresholds benefit the most.
KW - Cardiac Pacing, Artificial/methods
KW - Child
KW - Electrocardiography/instrumentation
KW - Equipment Design
KW - Equipment Failure Analysis
KW - Female
KW - Humans
KW - Longitudinal Studies
KW - Male
KW - Pacemaker, Artificial
KW - Pericardium
KW - Therapy, Computer-Assisted/instrumentation
KW - Treatment Outcome
U2 - 10.1093/europace/eum130
DO - 10.1093/europace/eum130
M3 - SCORING: Journal article
C2 - 17630391
VL - 9
SP - 645
EP - 650
JO - EUROPACE
JF - EUROPACE
SN - 1099-5129
IS - 8
ER -