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Long-term efficacy and safety of radiofrequency catheter ablation of atrial fibrillation in patients with cardiac implantable electronic devices and transvenous leads

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Long-term efficacy and safety of radiofrequency catheter ablation of atrial fibrillation in patients with cardiac implantable electronic devices and transvenous leads. / Dinshaw, Leon; Schäffer, Benjamin; Akbulak, Özge; Jularic, Mario; Hartmann, Jens; Klatt, Niklas; Dickow, Jannis; Gunawardene, Melanie; Münkler, Paula; Hakmi, Samer; Pecha, Simon; Sultan, Arian; Lüker, Jakob; Pinnschmidt, Hans; Hoffmann, Boris; Gosau, Nils; Eickholt, Christian; Willems, Stephan; Steven, Daniel; Meyer, Christian.

In: J CARDIOVASC ELECTR, Vol. 30, No. 5, 05.2019, p. 679-687.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Dinshaw, L, Schäffer, B, Akbulak, Ö, Jularic, M, Hartmann, J, Klatt, N, Dickow, J, Gunawardene, M, Münkler, P, Hakmi, S, Pecha, S, Sultan, A, Lüker, J, Pinnschmidt, H, Hoffmann, B, Gosau, N, Eickholt, C, Willems, S, Steven, D & Meyer, C 2019, 'Long-term efficacy and safety of radiofrequency catheter ablation of atrial fibrillation in patients with cardiac implantable electronic devices and transvenous leads', J CARDIOVASC ELECTR, vol. 30, no. 5, pp. 679-687. https://doi.org/10.1111/jce.13890

APA

Dinshaw, L., Schäffer, B., Akbulak, Ö., Jularic, M., Hartmann, J., Klatt, N., Dickow, J., Gunawardene, M., Münkler, P., Hakmi, S., Pecha, S., Sultan, A., Lüker, J., Pinnschmidt, H., Hoffmann, B., Gosau, N., Eickholt, C., Willems, S., Steven, D., & Meyer, C. (2019). Long-term efficacy and safety of radiofrequency catheter ablation of atrial fibrillation in patients with cardiac implantable electronic devices and transvenous leads. J CARDIOVASC ELECTR, 30(5), 679-687. https://doi.org/10.1111/jce.13890

Vancouver

Dinshaw L, Schäffer B, Akbulak Ö, Jularic M, Hartmann J, Klatt N et al. Long-term efficacy and safety of radiofrequency catheter ablation of atrial fibrillation in patients with cardiac implantable electronic devices and transvenous leads. J CARDIOVASC ELECTR. 2019 May;30(5):679-687. https://doi.org/10.1111/jce.13890

Bibtex

@article{df21a86dd17b40c2a9a7784d4382d2cf,
title = "Long-term efficacy and safety of radiofrequency catheter ablation of atrial fibrillation in patients with cardiac implantable electronic devices and transvenous leads",
abstract = "INTRODUCTION: Long-term efficacy and safety are uncertain in patients with cardiac implantable electronic devices (CIED) and transvenous leads (TVL) undergoing radiofrequency catheter ablation of atrial fibrillation (AF). Thus, we assessed the outcome of AF ablation in those patients during long-term follow-up using continuous atrial rhythm monitoring (CARM).METHODS AND RESULTS: A total of 190 patients (71.3 ± 10.7 years; 108 (56.8% men) were included in this study. At index procedure 81 (42.6%) patients presented with paroxysmal AF and 109 (57.4%) with persistent AF. The ablation strategy included pulmonary vein isolation in all patients and biatrial ablation of complex fractionated electrograms with additional ablation lines, if appropriate. AF recurrences were assessed by CARM- and CIED-related complications by device follow-up. After a mean follow-up of 55.4 ± 38.1 months, freedom of AF was found in 86 (61.4%) and clinical success defined as an AF burden less than or equal to 1% in 101 (72.1%) patients. Freedom of AF was reported in 74.6% and 51.9% (P = 0.006) and clinical success in 89.8% and 59.3% (P < 0.001) of patients with paroxysmal and persistent AF, respectively. In 3 of 408 (0.7%) ablation procedures, a TVL malfunction occurred within 90 days after catheter ablation. During long-term follow-up 9 (4.7%) patients showed lead dislodgement, 2 (1.1%) lead fracture, and 2 (1.1%) lead insulation defect not related to the ablation procedure.CONCLUSION: Our findings using CARM demonstrate long-term efficacy and safety of radiofrequency catheter ablation of AF in patients with CIED and TVL.",
keywords = "Journal Article",
author = "Leon Dinshaw and Benjamin Sch{\"a}ffer and {\"O}zge Akbulak and Mario Jularic and Jens Hartmann and Niklas Klatt and Jannis Dickow and Melanie Gunawardene and Paula M{\"u}nkler and Samer Hakmi and Simon Pecha and Arian Sultan and Jakob L{\"u}ker and Hans Pinnschmidt and Boris Hoffmann and Nils Gosau and Christian Eickholt and Stephan Willems and Daniel Steven and Christian Meyer",
note = "{\textcopyright} 2019 Wiley Periodicals, Inc.",
year = "2019",
month = may,
doi = "10.1111/jce.13890",
language = "English",
volume = "30",
pages = "679--687",
journal = "J CARDIOVASC ELECTR",
issn = "1045-3873",
publisher = "Wiley-Blackwell",
number = "5",

}

RIS

TY - JOUR

T1 - Long-term efficacy and safety of radiofrequency catheter ablation of atrial fibrillation in patients with cardiac implantable electronic devices and transvenous leads

AU - Dinshaw, Leon

AU - Schäffer, Benjamin

AU - Akbulak, Özge

AU - Jularic, Mario

AU - Hartmann, Jens

AU - Klatt, Niklas

AU - Dickow, Jannis

AU - Gunawardene, Melanie

AU - Münkler, Paula

AU - Hakmi, Samer

AU - Pecha, Simon

AU - Sultan, Arian

AU - Lüker, Jakob

AU - Pinnschmidt, Hans

AU - Hoffmann, Boris

AU - Gosau, Nils

AU - Eickholt, Christian

AU - Willems, Stephan

AU - Steven, Daniel

AU - Meyer, Christian

N1 - © 2019 Wiley Periodicals, Inc.

PY - 2019/5

Y1 - 2019/5

N2 - INTRODUCTION: Long-term efficacy and safety are uncertain in patients with cardiac implantable electronic devices (CIED) and transvenous leads (TVL) undergoing radiofrequency catheter ablation of atrial fibrillation (AF). Thus, we assessed the outcome of AF ablation in those patients during long-term follow-up using continuous atrial rhythm monitoring (CARM).METHODS AND RESULTS: A total of 190 patients (71.3 ± 10.7 years; 108 (56.8% men) were included in this study. At index procedure 81 (42.6%) patients presented with paroxysmal AF and 109 (57.4%) with persistent AF. The ablation strategy included pulmonary vein isolation in all patients and biatrial ablation of complex fractionated electrograms with additional ablation lines, if appropriate. AF recurrences were assessed by CARM- and CIED-related complications by device follow-up. After a mean follow-up of 55.4 ± 38.1 months, freedom of AF was found in 86 (61.4%) and clinical success defined as an AF burden less than or equal to 1% in 101 (72.1%) patients. Freedom of AF was reported in 74.6% and 51.9% (P = 0.006) and clinical success in 89.8% and 59.3% (P < 0.001) of patients with paroxysmal and persistent AF, respectively. In 3 of 408 (0.7%) ablation procedures, a TVL malfunction occurred within 90 days after catheter ablation. During long-term follow-up 9 (4.7%) patients showed lead dislodgement, 2 (1.1%) lead fracture, and 2 (1.1%) lead insulation defect not related to the ablation procedure.CONCLUSION: Our findings using CARM demonstrate long-term efficacy and safety of radiofrequency catheter ablation of AF in patients with CIED and TVL.

AB - INTRODUCTION: Long-term efficacy and safety are uncertain in patients with cardiac implantable electronic devices (CIED) and transvenous leads (TVL) undergoing radiofrequency catheter ablation of atrial fibrillation (AF). Thus, we assessed the outcome of AF ablation in those patients during long-term follow-up using continuous atrial rhythm monitoring (CARM).METHODS AND RESULTS: A total of 190 patients (71.3 ± 10.7 years; 108 (56.8% men) were included in this study. At index procedure 81 (42.6%) patients presented with paroxysmal AF and 109 (57.4%) with persistent AF. The ablation strategy included pulmonary vein isolation in all patients and biatrial ablation of complex fractionated electrograms with additional ablation lines, if appropriate. AF recurrences were assessed by CARM- and CIED-related complications by device follow-up. After a mean follow-up of 55.4 ± 38.1 months, freedom of AF was found in 86 (61.4%) and clinical success defined as an AF burden less than or equal to 1% in 101 (72.1%) patients. Freedom of AF was reported in 74.6% and 51.9% (P = 0.006) and clinical success in 89.8% and 59.3% (P < 0.001) of patients with paroxysmal and persistent AF, respectively. In 3 of 408 (0.7%) ablation procedures, a TVL malfunction occurred within 90 days after catheter ablation. During long-term follow-up 9 (4.7%) patients showed lead dislodgement, 2 (1.1%) lead fracture, and 2 (1.1%) lead insulation defect not related to the ablation procedure.CONCLUSION: Our findings using CARM demonstrate long-term efficacy and safety of radiofrequency catheter ablation of AF in patients with CIED and TVL.

KW - Journal Article

U2 - 10.1111/jce.13890

DO - 10.1111/jce.13890

M3 - SCORING: Journal article

C2 - 30821012

VL - 30

SP - 679

EP - 687

JO - J CARDIOVASC ELECTR

JF - J CARDIOVASC ELECTR

SN - 1045-3873

IS - 5

ER -