Liquid ecstasy - a significant drug problem.
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Liquid ecstasy - a significant drug problem. / Andresen, Hilke; Stimpfl, Thomas; Sprys, Nadine; Schnitgerhans, Tino; Müller, Alexander.
In: DTSCH ARZTEBL INT, Vol. 105, No. 36, 36, 2008, p. 599-603.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Liquid ecstasy - a significant drug problem.
AU - Andresen, Hilke
AU - Stimpfl, Thomas
AU - Sprys, Nadine
AU - Schnitgerhans, Tino
AU - Müller, Alexander
PY - 2008
Y1 - 2008
N2 - INTRODUCTION: Gamma-hydroxybutyric acid (GHB, "liquid ecstasy") and its legal pro-drugs gamma-butyrolactone and 1,4-butanediol are gaining in importance as recreational drugs in Germany. The effects of these substances are comparable with those of alcohol or benzodiazepines. Because of the wide availability of GHB physicians are increasingly being confronted with cases of intoxication. METHODS: This review is based on a selective literature search as well as on the authors' own experience and on information provided by the GIZ-Nord Poisons Centre, Göttingen, Germany. RESULTS: Consumption of a high dose of GHB or its prodrugs leads to severe intoxication with respiratory depression and coma. Only supportive therapy can be offered; no antidote is available. DISCUSSION: In any patient with impaired consciousness of unknown cause, the possibility of intoxication with GHB must be considered. Chemical detection of GHB in blood or urine is possible only using specific analytical methods and only within a short time frame (
AB - INTRODUCTION: Gamma-hydroxybutyric acid (GHB, "liquid ecstasy") and its legal pro-drugs gamma-butyrolactone and 1,4-butanediol are gaining in importance as recreational drugs in Germany. The effects of these substances are comparable with those of alcohol or benzodiazepines. Because of the wide availability of GHB physicians are increasingly being confronted with cases of intoxication. METHODS: This review is based on a selective literature search as well as on the authors' own experience and on information provided by the GIZ-Nord Poisons Centre, Göttingen, Germany. RESULTS: Consumption of a high dose of GHB or its prodrugs leads to severe intoxication with respiratory depression and coma. Only supportive therapy can be offered; no antidote is available. DISCUSSION: In any patient with impaired consciousness of unknown cause, the possibility of intoxication with GHB must be considered. Chemical detection of GHB in blood or urine is possible only using specific analytical methods and only within a short time frame (
M3 - SCORING: Zeitschriftenaufsatz
VL - 105
SP - 599
EP - 603
JO - DTSCH ARZTEBL INT
JF - DTSCH ARZTEBL INT
SN - 1866-0452
IS - 36
M1 - 36
ER -
