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Limitations of imaging choroidal tumors in vivo by optical coherence tomography

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Limitations of imaging choroidal tumors in vivo by optical coherence tomography. / Schaudig, U; Hassenstein, A; Bernd, A; Walter, A; Richard, G.

In: GRAEF ARCH CLIN EXP, Vol. 236, No. 8, 01.08.1998, p. 588-92.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Schaudig, U, Hassenstein, A, Bernd, A, Walter, A & Richard, G 1998, 'Limitations of imaging choroidal tumors in vivo by optical coherence tomography', GRAEF ARCH CLIN EXP, vol. 236, no. 8, pp. 588-92.

APA

Schaudig, U., Hassenstein, A., Bernd, A., Walter, A., & Richard, G. (1998). Limitations of imaging choroidal tumors in vivo by optical coherence tomography. GRAEF ARCH CLIN EXP, 236(8), 588-92.

Vancouver

Schaudig U, Hassenstein A, Bernd A, Walter A, Richard G. Limitations of imaging choroidal tumors in vivo by optical coherence tomography. GRAEF ARCH CLIN EXP. 1998 Aug 1;236(8):588-92.

Bibtex

@article{fc1e4d35db2d458eb7019ab691032b25,
title = "Limitations of imaging choroidal tumors in vivo by optical coherence tomography",
abstract = "BACKGROUND: Optical coherence tomography (OCT) produces two-dimensional cross-sectional images with a longitudinal resolution of 10 microns. Its capacity for imaging retinal structure has been shown in a variety of diseases. There are no reports on its capacity and limitations in imaging choriocapillary and choroidal structures.METHODS: Twenty-two patients with the diagnosis of malignant melanoma of the choroid were submitted to OCT. We used a prototype and a commercial device, both with an 850-nm superluminescent diode with a band-width of 30 nm (reported longitudinal resolution 10 microns). The images were evaluated for retinal thickness, changes in retinal pigment epithelium, subretinal fluid accumulation and changes in choriocapillary or choroidal reflectivity.RESULTS: Retinal edema and detachment found on biomicroscopic examination for fluorescein angiography was detected by OCT in all such cases. In 2 of 22 cases small retinal detachments were detected only by OCT. Tumor extension through the retinal pigment epithelium was not seen in this series, either by biomicroscopy or by OCT. The pattern of choroidal or choriocapillary reflectivity was nonspecifically lower than that of normal choroid, but did not yield any additional information about tumor histology. When normal retina was present, the OCT appearance of a malignant melanoma resembled that of normal choroid.CONCLUSION: OCT may provide information about the retinal structure overlying prominent tumors and the extent of adjacent retinal detachment. In its present state of development, OCT is of little value in the differential diagnosis of choroidal tumors. Its potential value for the follow-up of shallow tumors needs further investigation.",
keywords = "Adult, Aged, Choroid, Choroid Neoplasms, Exudates and Transudates, Female, Humans, Interferometry, Light, Male, Melanoma, Middle Aged, Pigment Epithelium of Eye, Retina, Retinal Detachment, Tomography",
author = "U Schaudig and A Hassenstein and A Bernd and A Walter and G Richard",
year = "1998",
month = aug,
day = "1",
language = "English",
volume = "236",
pages = "588--92",
journal = "GRAEF ARCH CLIN EXP",
issn = "0721-832X",
publisher = "Springer",
number = "8",

}

RIS

TY - JOUR

T1 - Limitations of imaging choroidal tumors in vivo by optical coherence tomography

AU - Schaudig, U

AU - Hassenstein, A

AU - Bernd, A

AU - Walter, A

AU - Richard, G

PY - 1998/8/1

Y1 - 1998/8/1

N2 - BACKGROUND: Optical coherence tomography (OCT) produces two-dimensional cross-sectional images with a longitudinal resolution of 10 microns. Its capacity for imaging retinal structure has been shown in a variety of diseases. There are no reports on its capacity and limitations in imaging choriocapillary and choroidal structures.METHODS: Twenty-two patients with the diagnosis of malignant melanoma of the choroid were submitted to OCT. We used a prototype and a commercial device, both with an 850-nm superluminescent diode with a band-width of 30 nm (reported longitudinal resolution 10 microns). The images were evaluated for retinal thickness, changes in retinal pigment epithelium, subretinal fluid accumulation and changes in choriocapillary or choroidal reflectivity.RESULTS: Retinal edema and detachment found on biomicroscopic examination for fluorescein angiography was detected by OCT in all such cases. In 2 of 22 cases small retinal detachments were detected only by OCT. Tumor extension through the retinal pigment epithelium was not seen in this series, either by biomicroscopy or by OCT. The pattern of choroidal or choriocapillary reflectivity was nonspecifically lower than that of normal choroid, but did not yield any additional information about tumor histology. When normal retina was present, the OCT appearance of a malignant melanoma resembled that of normal choroid.CONCLUSION: OCT may provide information about the retinal structure overlying prominent tumors and the extent of adjacent retinal detachment. In its present state of development, OCT is of little value in the differential diagnosis of choroidal tumors. Its potential value for the follow-up of shallow tumors needs further investigation.

AB - BACKGROUND: Optical coherence tomography (OCT) produces two-dimensional cross-sectional images with a longitudinal resolution of 10 microns. Its capacity for imaging retinal structure has been shown in a variety of diseases. There are no reports on its capacity and limitations in imaging choriocapillary and choroidal structures.METHODS: Twenty-two patients with the diagnosis of malignant melanoma of the choroid were submitted to OCT. We used a prototype and a commercial device, both with an 850-nm superluminescent diode with a band-width of 30 nm (reported longitudinal resolution 10 microns). The images were evaluated for retinal thickness, changes in retinal pigment epithelium, subretinal fluid accumulation and changes in choriocapillary or choroidal reflectivity.RESULTS: Retinal edema and detachment found on biomicroscopic examination for fluorescein angiography was detected by OCT in all such cases. In 2 of 22 cases small retinal detachments were detected only by OCT. Tumor extension through the retinal pigment epithelium was not seen in this series, either by biomicroscopy or by OCT. The pattern of choroidal or choriocapillary reflectivity was nonspecifically lower than that of normal choroid, but did not yield any additional information about tumor histology. When normal retina was present, the OCT appearance of a malignant melanoma resembled that of normal choroid.CONCLUSION: OCT may provide information about the retinal structure overlying prominent tumors and the extent of adjacent retinal detachment. In its present state of development, OCT is of little value in the differential diagnosis of choroidal tumors. Its potential value for the follow-up of shallow tumors needs further investigation.

KW - Adult

KW - Aged

KW - Choroid

KW - Choroid Neoplasms

KW - Exudates and Transudates

KW - Female

KW - Humans

KW - Interferometry

KW - Light

KW - Male

KW - Melanoma

KW - Middle Aged

KW - Pigment Epithelium of Eye

KW - Retina

KW - Retinal Detachment

KW - Tomography

M3 - SCORING: Journal article

C2 - 9717654

VL - 236

SP - 588

EP - 592

JO - GRAEF ARCH CLIN EXP

JF - GRAEF ARCH CLIN EXP

SN - 0721-832X

IS - 8

ER -