Latent mycobacterium avium infection causing a mycotic suprarenal aortic aneurysm in a human immunodeficiency virus-positive patient
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Latent mycobacterium avium infection causing a mycotic suprarenal aortic aneurysm in a human immunodeficiency virus-positive patient. / Tsilimparis, Nikolaos; Defreitas, Dorian; Debus, E Sebastian; Reeves, James G.
In: ANN VASC SURG, Vol. 28, No. 4, 05.2014, p. 1035.e1-4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Latent mycobacterium avium infection causing a mycotic suprarenal aortic aneurysm in a human immunodeficiency virus-positive patient
AU - Tsilimparis, Nikolaos
AU - Defreitas, Dorian
AU - Debus, E Sebastian
AU - Reeves, James G
N1 - Copyright © 2014 Elsevier Inc. All rights reserved.
PY - 2014/5
Y1 - 2014/5
N2 - Mycobacterium avium complex (MAC) infection occurs in up to 50% of advanced-stage human immunodeficiency 1 (HIV-1) infections when the CD4 counts is <50/mm³. We report the case of a 52-year-old HIV-positive patient who presented with a symptomatic, rapidly growing suprarenal abdominal aortic aneurysm. He had been diagnosed and treated for disseminated MAC infection 3 years earlier. He was treated with antiretroviral medications and had a CD4 count >250 cells/mm³ and an undetectable viral load. Open repair was performed using cryopreserved homograft. Microbiologic cultures from the specimen revealed infection with mycobacterium avium. This is the first case to report a mycotic suprarenal aortic aneurysm caused by an active conversion of a latent MAC infection.
AB - Mycobacterium avium complex (MAC) infection occurs in up to 50% of advanced-stage human immunodeficiency 1 (HIV-1) infections when the CD4 counts is <50/mm³. We report the case of a 52-year-old HIV-positive patient who presented with a symptomatic, rapidly growing suprarenal abdominal aortic aneurysm. He had been diagnosed and treated for disseminated MAC infection 3 years earlier. He was treated with antiretroviral medications and had a CD4 count >250 cells/mm³ and an undetectable viral load. Open repair was performed using cryopreserved homograft. Microbiologic cultures from the specimen revealed infection with mycobacterium avium. This is the first case to report a mycotic suprarenal aortic aneurysm caused by an active conversion of a latent MAC infection.
KW - Allografts
KW - Aneurysm, Infected/diagnosis
KW - Anti-Bacterial Agents/therapeutic use
KW - Anti-HIV Agents/therapeutic use
KW - Aortic Aneurysm, Abdominal/diagnosis
KW - Aortography/methods
KW - Bioprosthesis
KW - Blood Vessel Prosthesis
KW - Blood Vessel Prosthesis Implantation/instrumentation
KW - Coinfection
KW - Cryopreservation
KW - HIV Infections/diagnosis
KW - HIV-1/isolation & purification
KW - Humans
KW - Male
KW - Middle Aged
KW - Mycobacterium avium Complex/isolation & purification
KW - Mycobacterium avium-intracellulare Infection/diagnosis
KW - Tomography, X-Ray Computed
KW - Treatment Outcome
U2 - 10.1016/j.avsg.2013.06.036
DO - 10.1016/j.avsg.2013.06.036
M3 - SCORING: Journal article
C2 - 24556183
VL - 28
SP - 1035.e1-4
JO - ANN VASC SURG
JF - ANN VASC SURG
SN - 0890-5096
IS - 4
ER -