Latent mycobacterium avium infection causing a mycotic suprarenal aortic aneurysm in a human immunodeficiency virus-positive patient

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Latent mycobacterium avium infection causing a mycotic suprarenal aortic aneurysm in a human immunodeficiency virus-positive patient. / Tsilimparis, Nikolaos; Defreitas, Dorian; Debus, E Sebastian; Reeves, James G.

In: ANN VASC SURG, Vol. 28, No. 4, 05.2014, p. 1035.e1-4.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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@article{62355a3571d34db19e2e71bde14dde23,
title = "Latent mycobacterium avium infection causing a mycotic suprarenal aortic aneurysm in a human immunodeficiency virus-positive patient",
abstract = "Mycobacterium avium complex (MAC) infection occurs in up to 50% of advanced-stage human immunodeficiency 1 (HIV-1) infections when the CD4 counts is <50/mm³. We report the case of a 52-year-old HIV-positive patient who presented with a symptomatic, rapidly growing suprarenal abdominal aortic aneurysm. He had been diagnosed and treated for disseminated MAC infection 3 years earlier. He was treated with antiretroviral medications and had a CD4 count >250 cells/mm³ and an undetectable viral load. Open repair was performed using cryopreserved homograft. Microbiologic cultures from the specimen revealed infection with mycobacterium avium. This is the first case to report a mycotic suprarenal aortic aneurysm caused by an active conversion of a latent MAC infection. ",
keywords = "Allografts, Aneurysm, Infected/diagnosis, Anti-Bacterial Agents/therapeutic use, Anti-HIV Agents/therapeutic use, Aortic Aneurysm, Abdominal/diagnosis, Aortography/methods, Bioprosthesis, Blood Vessel Prosthesis, Blood Vessel Prosthesis Implantation/instrumentation, Coinfection, Cryopreservation, HIV Infections/diagnosis, HIV-1/isolation & purification, Humans, Male, Middle Aged, Mycobacterium avium Complex/isolation & purification, Mycobacterium avium-intracellulare Infection/diagnosis, Tomography, X-Ray Computed, Treatment Outcome",
author = "Nikolaos Tsilimparis and Dorian Defreitas and Debus, {E Sebastian} and Reeves, {James G}",
note = "Copyright {\textcopyright} 2014 Elsevier Inc. All rights reserved.",
year = "2014",
month = may,
doi = "10.1016/j.avsg.2013.06.036",
language = "English",
volume = "28",
pages = "1035.e1--4",
journal = "ANN VASC SURG",
issn = "0890-5096",
publisher = "Elsevier Inc.",
number = "4",

}

RIS

TY - JOUR

T1 - Latent mycobacterium avium infection causing a mycotic suprarenal aortic aneurysm in a human immunodeficiency virus-positive patient

AU - Tsilimparis, Nikolaos

AU - Defreitas, Dorian

AU - Debus, E Sebastian

AU - Reeves, James G

N1 - Copyright © 2014 Elsevier Inc. All rights reserved.

PY - 2014/5

Y1 - 2014/5

N2 - Mycobacterium avium complex (MAC) infection occurs in up to 50% of advanced-stage human immunodeficiency 1 (HIV-1) infections when the CD4 counts is <50/mm³. We report the case of a 52-year-old HIV-positive patient who presented with a symptomatic, rapidly growing suprarenal abdominal aortic aneurysm. He had been diagnosed and treated for disseminated MAC infection 3 years earlier. He was treated with antiretroviral medications and had a CD4 count >250 cells/mm³ and an undetectable viral load. Open repair was performed using cryopreserved homograft. Microbiologic cultures from the specimen revealed infection with mycobacterium avium. This is the first case to report a mycotic suprarenal aortic aneurysm caused by an active conversion of a latent MAC infection.

AB - Mycobacterium avium complex (MAC) infection occurs in up to 50% of advanced-stage human immunodeficiency 1 (HIV-1) infections when the CD4 counts is <50/mm³. We report the case of a 52-year-old HIV-positive patient who presented with a symptomatic, rapidly growing suprarenal abdominal aortic aneurysm. He had been diagnosed and treated for disseminated MAC infection 3 years earlier. He was treated with antiretroviral medications and had a CD4 count >250 cells/mm³ and an undetectable viral load. Open repair was performed using cryopreserved homograft. Microbiologic cultures from the specimen revealed infection with mycobacterium avium. This is the first case to report a mycotic suprarenal aortic aneurysm caused by an active conversion of a latent MAC infection.

KW - Allografts

KW - Aneurysm, Infected/diagnosis

KW - Anti-Bacterial Agents/therapeutic use

KW - Anti-HIV Agents/therapeutic use

KW - Aortic Aneurysm, Abdominal/diagnosis

KW - Aortography/methods

KW - Bioprosthesis

KW - Blood Vessel Prosthesis

KW - Blood Vessel Prosthesis Implantation/instrumentation

KW - Coinfection

KW - Cryopreservation

KW - HIV Infections/diagnosis

KW - HIV-1/isolation & purification

KW - Humans

KW - Male

KW - Middle Aged

KW - Mycobacterium avium Complex/isolation & purification

KW - Mycobacterium avium-intracellulare Infection/diagnosis

KW - Tomography, X-Ray Computed

KW - Treatment Outcome

U2 - 10.1016/j.avsg.2013.06.036

DO - 10.1016/j.avsg.2013.06.036

M3 - SCORING: Journal article

C2 - 24556183

VL - 28

SP - 1035.e1-4

JO - ANN VASC SURG

JF - ANN VASC SURG

SN - 0890-5096

IS - 4

ER -