Lack of evidence for pleiotropic effects of clopidogrel on endothelial function and inflammation in patients with stable coronary artery disease: results of the double-blind, randomized CASSANDRA study.

  • Mir Abolfazl Ostad
  • Eva Nick
  • Vitor Paixao-Gatinho
  • Boris Schnorbus
  • Robert Schiewe
  • Peter Tschentscher
  • Thomas Munzel
  • Ascan Warnholtz

Abstract

Recently we have demonstrated a dose-dependent improvement of endothelial function after administration of a single loading dose of clopidogrel in patients with coronary artery disease (CAD). We therefore hypothesized that chronic therapy with clopidogrel may improve endothelial function in patients with CAD.

Bibliographical data

Original languageGerman
Article number1
ISSN1861-0684
Publication statusPublished - 2011
pubmed 20644943